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Structural Variability (schematic)

(Average deviation from average C-alpha positions)

VL all
VL kappa
VL lambda

VH all
VH Type I (H6=Glu, H9=Pro)
VH Type II (H6=Glu, H9=Gly)
VH Type III (H6=Gln, H7=Ser)
VH Type IV (H6=Gln, H7=Pro)
 

Interactive Structure Display

VL kappa (PDB entry 1a2y)
VL lambda (PDB entry 1aqk)
VH Type I (H6=Glu, H9=Pro) (PDB entry 12e8)
VH Type II (H6=Glu, H9=Gly) (PDB entry 1aqk)
VH Type III (H6=Gln, H7=Ser) (PDB entry 1a7n)
VH Type IV (H6=Gln, H7=Pro) (PDB entry 1cic2)

 Deviation of C-alpha Positions from Average VL Structure

VL all, VL kappa, VL lambda, VH all, VH(EP), VH(EG), VH(QS), VH(QP)
AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Wednesday, January 26, 2005