Introduction Numbering Sequences Structures Modelling Macros Publications Links
Homology Modelling CDR Grafting Examples HuCAL Biophysical Properties Randomization Catalytic Antibodies

Top
Antigen Contact Residues in Protein Binders

Hapten Binders (top view)
Oligomer Binders (top view)
Protein Binders (top view)

Color Code

Bottom, left to right:
Sequence Variability in HuCAL I (only CDR 3 randomized), in HuCAL II (all CDRs randomized) and in natural human Antibodies

Chime Display

HuCAL I (CDR 3 randomized, all Frameworks)

 HuCAL II (all CDRs randomized, all FR)  natural human Antibodies
AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Thursday, November 8, 2001