Introduction Numbering Sequences Structures Modelling Macros Publications Links
Homology Modelling CDR Grafting Examples HuCAL Biophysical Properties Randomization Catalytic Antibodies

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Antigen Contact Residues in Hapten Binders

Hapten Binders (top view)
Oligomer Binders (top view)
Protein Binders (top view)

Bottom, left to right:
Sequence Variability in HuCAL I (only CDR3 randomized), in HuCAL II (all CDRs randomized) and in natural human Antibodies

Chime Display

HuCAL I (CDR3 randomized, all Frameworks)

 HuCAL II (all CDR randomized, all FR)  natural human Antibodies
AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Thursday, November 8, 2001