Introduction Numbering Sequences Structures Modelling Macros Publications Links
Homology Modelling CDR Grafting Examples HuCAL Biophysical Properties Randomization Catalytic Antibodies

Color CDR

Sequence Variability:

natural human antibodies (ca. 2000 Sequences from the Kabat Database)
HuCAL I VK2/VH3 (single Framework)
HuCAL I (only CDR1 randomized, all frameworks)
HuCAL II (all three CDRs randomized, all frameworks)

Antigen Contacts

Protein Binders
Oligomer Binder
Hapten Binders
Catalytic Antibodies

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AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Friday, February 27, 2009