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Immunoglobulin IgG Structure

IgG1 Structure - 1igy - CH-Domain

Secondary structure cartoon
a-Helix: red
b-Sheet: yellow
Turn: dark blue
Random coil: green
Ribbon colored according to chain
light chains: pink, magenta
heavy chains: cyan, blue
SS-bonds yellow
Ribbon colored according to domain
VL: magenta
CL: pink
VH: blue
CH: cyan
Hinge: blue-green
CH2: green
CH3: yellow-green
sugar residues: white,cpk
Antigen contact residues (Average over all antigen complexes)
red: strong contact, >80% reduction in accessibility upon comples formation
red-orange: 60-80% reduction
orange: 40-60% reduction
yellow-orange: 20-40% reduction
yellow: <20% reduction
white: no contact
VL/VH contact residues
CL/CH contact residues
VL/CL and VH/CH contact residues
no direct CH2/CH2 protein-protein contacts
CH3/CH3 contact residues
CH2/CH3 contact residues
AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Tuesday, January 25, 2005