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Importins

Structure ID  Title Authors Publication Year Journal Name Volume ID First Page Pubmed
1BK5 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Conti, E., Uy, M., Leighton, L., Blobel, G., Kuriyan, J. 1998 Cell 94 193 9695948
1BK6 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Conti, E., Uy, M., Leighton, L., Blobel, G., Kuriyan, J. 1998 Cell 94 193 9695948
1EE4 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Conti, E., Kuriyan, J. 2000 Structure Fold.Des. 8 329 10745017
1EE5 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Conti, E., Kuriyan, J. 2000 Structure Fold.Des. 8 329 10745017
1EFX Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Boyington, J.C., Motyka, S.A., Schuck, P., Brooks, A.G., Sun, P.D. 2000 Nature 405 537 10850706
1EJL Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha. Fontes, M.R., Teh, T., Kobe, B. 2000 J.Mol.Biol. 297 1183 10764582
1EJY Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha. Fontes, M.R., Teh, T., Kobe, B. 2000 J.Mol.Biol. 297 1183 10764582
1F59 Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Bayliss, R., Littlewood, T., Stewart, M. 2000 Cell 102 99 10929717
1GCJ The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. Lee, S.J., Imamoto, N., Sakai, H., Nakagawa, A., Kose, S., Koike, M., Yamamoto, M., Kumasaka, T., Yoneda, Y., Tsukihara, T. 2000 J.Mol.Biol. 302 251 10964573
1IAL Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha. Kobe, B. 1999 Nat.Struct.Biol. 6 388 10201409
1IBR Structural view of the Ran-Importin beta interaction at 2.3 A resolution Vetter, I.R., Arndt, A., Kutay, U., Gorlich, D., Wittinghofer, A. 1999 Cell (Cambridge,Mass.) 97 635 10367892
1IQ1 Biophysical characterization of interactions involving importin-alpha during nuclear import. Catimel, B., Teh, T., Fontes, M.R., Jennings, I.G., Jans, D.A., Howlett, G.J., Nice, E.C., Kobe, B. 2001 J.Biol.Chem. 276 34189 11448961
1M5N Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta Cingolani, G., Bednenko, J., Gillespie, M.T., Gerace, L. 2002 Mol. Cell 10 1345 12504010
1O6O Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta Bayliss, R., Littlewood, T., Strawn, L.A., Wente, S.R., Stewart, M. 2002 J.Biol.Chem. 277 50597 n/a
1O6P Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta Bayliss, R., Littlewood, T., Strawn, L.A., Wente, S.R., Stewart, M. 2002 J.Biol.Chem. 277 50597 n/a
1PJM Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha Fontes, M.R.M., Teh, T., Jans, D., Brinkworth, R.I., Kobe, B. 2003 J.Biol.Chem. 278 27981 12695505
1PJN Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha Fontes, M.R.M., Teh, T., Jans, D., Brinkworth, R.I., Kobe, B. 2003 J.Biol.Chem. 278 27981 12695505
1Q1S Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Fontes, M.R.M., Teh, T., Toth, G., John, A., Pavo, I., Jans, D.A., Kobe, B. 2003 Biochem.J. 375 339 12852786
1Q1T Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Fontes, M.R.M., Teh, T., Toth, G., John, A., Pavo, I., Jans, D.A., Kobe, B. 2003 Biochem.J. 375 339 12852786
1QBK Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Chook, Y.M., Blobel, G. 1999 Nature 399 230 10353245
1QGK Structure of importin-beta bound to the IBB domain of importin-alpha. Cingolani, G., Petosa, C., Weis, K., Muller, C.W. 1999 Nature 399 221 10353244
1QGR Structure of importin-beta bound to the IBB domain of importin-alpha. Cingolani, G., Petosa, C., Weis, K., Muller, C.W. 1999 Nature 399 221 10353244
1RRP Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Vetter, I.R., Nowak, C., Nishimoto, T., Kuhlmann, J., Wittinghofer, A. 1999 Nature 398 39 10078529
1UKL The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor Lee, S.J., Sekimoto, T., Yamashita, E., Nagoshi, E., Nakagawa, A., Imamoto, N., Yoshimura, M., Sakai, H., Chong, K.T., Tsukihara, T., Yoneda, Y. 2003 Science 302 1571 14645851
1UN0 Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import Matsuura, Y., Lange, A., Harreman, M., Corbett, A., Stewart, M. 2003 Embo J. 22 5358 n/a
1W3B The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha Jinek, M., Rehwinkel, J., Lazarus, B.D., Izaurralde, E., Hanover, J.A., Conti, E. 2004 Nat.Struct.Mol.Biol. 11 1001 n/a
1WA5 Structural Basis for the Assembly of a Nuclear Export Complex Matsuura, Y., Stewart, M. 2004 Nature 432 872 n/a
1Y2A Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha Chen, M.-H., Ben-Efraim, I., Mitrousis, G., Walker-Kopp, N., Sims, P.J., Cingolani, G. 2005 J.Biol.Chem. 280 10599 15611084
1Z3H The structure of the nuclear export receptor cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding Cook, A., Fernandez, E., Lindner, D., Ebert, J., Schlenstedt, G., Conti, E. 2005 Mol.Cell 18 355 15866177
2BKU Structural Basis for Nuclear Import Complex Dissociation by Rangtp Lee, S.J., Matsuura, Y., Liu, S.M., Stewart, M. 2005 Nature 435 693 n/a
2BPT Structural Basis for the High-Affinity Binding of Nucleoporin Nup1P to the Saccharomyces Cerevisiae Importin-Beta Homologue, Kap95P Liu, S.M., Stewart, M. 2005 J.Mol.Biol. 349 515 n/a
2C1M Nup50/Npap60 Function in Nuclear Protein Import Complex Disassembly and Importin Recycling. Matsuura, Y., Stewart, M. 2005 Embo J. 24 3681 n/a
2C1T Nup50/Npap60 Function in Nuclear Import Complex Disassembly and Importin Recycling Matsuura, Y., Stewart, M. 2005 Embo J. 24 3681 n/a
2H4M Rules for nuclear localization sequence recognition by karyopherin beta 2. Lee, B.J., Cansizoglu, A.E., Louis, T.H., Zhang, Z., Chook, Y.M. 2006 Cell 126 543 16901787

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Last changed by: A.Honegger, 8/6/08