Choices for Biosensors

Other enzymes that oxidize glucose are also used as glucose monitors. Two glucose dehydrogenases that are being explored for use in biosensors are shown here. At the top is an enzyme that uses NAD as the cofactor to perform the oxidation reaction (PDB entry 1gco), and the enzyme at the bottom (PDB entry 1cq1) uses an unusual pyrroloquinoline quinone cofactor.