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Kinesin

Kinesin

This Way or That?

Our cells build about 40 different types of kinesin for different functions. They all have a similar motor domain that uses ATP to perform its power stroke. But this motor is attached to many different types of adapters that attach the motor to the object that needs to be moved. Two kinesins are shown here--conventional kinesin at the top (PDB entry 2kin) and ncd at the bottom (PDB entry 2ncd). Notice that the two motor domains are connected differently to the stalk. The result of this difference is that these two kinesins move in opposite directions on the microtubule.

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Last changed by: A.Honegger, 8/15/06