	Inhaltsübersicht \| Nanomaschinen \| Moleküle \| Programme \| Kurse \| Fun \| Links
Kontakt \| Home	>

Dengue Virus

Untersuchen Sie die abgebildeten Molekuele genauer:

Welche Form hat das Molekuel?

Wie sind die hydrophoben Aminosaeuren im Molekuel verteilt?

Wie sind die elektrisch geladenen Reste verteilt?

Aus wievielen Ketten besteht das Protein (Quartaerstruktur)?

Orientierung der Ketten: Nterm (blau) -> Cterm (rot)

Wie sind diese gefaltet (Sekundaerstruktur)?

Enthaelt das Protein auch nicht-Protein-Anteile? Welche? Was ist deren Funktion?

Nukleinsaeuren hervorheben

kleinmolekulare Bestandteile hervorheben: Label ein/aus

Loesungsmittelmolekuele hervorheben

Dengue Virus with Antibodies (PDB entry 2r6p)

This structure contains the envelope protein of dengue virus (white) with antibody Fab fragments (blue) bound on the surface. This Jmol includes only the asymmetric unit of the structure, which includes three copies of the envelope protein and two antibody Fab molecules. Also, since the structure includes only the positions of one carbon atom in each amino acid, a thick backbone diagram is used to display the structure. Compare the two envelope proteins that are bound to the antibodies with the one that is not bound, and notice how the antibodies distort the structure of the protein.

If you would like to try looking at the whole virus structure, click here. Please note that this may take a long time to load, and may fail entirely on some computers, since there are over 120,000 atoms in the structure!

Previous: Exploring the Structure

Last changed by: A.Honegger, 10/31/08