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Prions
A list of prion related entries in the PDB
as determined by a keyword search on April 30, 2008
| Structure ID | Title | Authors | Publication Year | Journal Name | Volume ID | First Page | Pubmed |
| 1AG2 | NMR structure of the mouse prion protein domain PrP(121-321). | Riek, R., Hornemann, S., Wider, G., Billeter, M., Glockshuber, R., Wuthrich, K. | 1996 | Nature | 382 | 180 | 8700211 |
| 1B10 | Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. | James, T.L., Liu, H., Ulyanov, N.B., Farr-Jones, S., Zhang, H., Donne, D.G., Kaneko, K., Groth, D., Mehlhorn, I., Prusiner, S.B., Cohen, F.E. | 1997 | Proc.Natl.Acad.Sci.USA | 94 | 10086 | 9294167 |
| 1CR9 | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. | Kanyo, Z.F., Pan, K.M., Williamson, R.A., Burton, D.R., Prusiner, S.B., Fletterick, R.J., Cohen, F.E. | 1999 | J.Mol.Biol. | 293 | 855 | 10543972 |
| 1CU4 | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. | Kanyo, Z.F., Pan, K.M., Williamson, R.A., Burton, D.R., Prusiner, S.B., Fletterick, R.J., Cohen, F.E. | 1999 | J.Mol.Biol. | 293 | 855 | 10543972 |
| 1DWY | NMR structure of the bovine prion protein. | Lopez Garcia, F., Zahn, R., Riek, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.Usa | 97 | 8334 | 10899999 |
| 1DWZ | NMR structure of the bovine prion protein. | Lopez Garcia, F., Zahn, R., Riek, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.Usa | 97 | 8334 | 10899999 |
| 1DX0 | NMR structure of the bovine prion protein. | Lopez Garcia, F., Zahn, R., Riek, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.Usa | 97 | 8334 | 10899999 |
| 1DX1 | NMR structure of the bovine prion protein. | Lopez Garcia, F., Zahn, R., Riek, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.Usa | 97 | 8334 | 10899999 |
| 1E1G | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1E1J | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1E1P | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1E1S | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1E1U | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1E1W | NMR structures of three single-residue variants of the human prion protein. | Calzolai, L., Lysek, D.A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 8340 | 10900000 |
| 1FKC | Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases. | Zhang, Y., Swietnicki, W., Zagorski, M.G., Surewicz, W.K., Sonnichsen, F.D. | 2000 | J.Biol.Chem. | 275 | 33650 | 10954699 |
| 1FO7 | Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases. | Zhang, Y., Swietnicki, W., Zagorski, M.G., Surewicz, W.K., Sonnichsen, F.D. | 2000 | J.Biol.Chem. | 275 | 33650 | 10954699 |
| 1G04 | Sheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solution. | Kozin, S.A., Bertho, G., Mazur, A.K., Rabesona, H., Girault, J.P., Haertle, T., Takahashi, M., Debey, P., Hoa, G.H. | 2001 | J.Biol.Chem. | 276 | 46364 | 11577109 |
| 1G6W | Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae. | Bousset, L., Belrhali, H., Janin, J., Melki, R., Morera, S. | 2001 | Structure | 9 | 39 | 11342133 |
| 1G6Y | Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae. | Bousset, L., Belrhali, H., Janin, J., Melki, R., Morera, S. | 2001 | Structure | 9 | 39 | 11342133 |
| 1H0L | NMR structure of a variant human prion protein with two disulfide bridges. | Zahn, R., Guntert, P., von Schroetter, C., Wuthrich, K. | 2003 | J.Mol.Biol. | 326 | 225 | 12547204 |
| 1HJM | Influence of pH on NMR structure and stability of the human prion protein globular domain. | Calzolai, L., Zahn, R. | 2003 | J.Biol.Chem. | 278 | 35592 | 12826672 |
| 1HJN | Influence of pH on NMR structure and stability of the human prion protein globular domain. | Calzolai, L., Zahn, R. | 2003 | J.Biol.Chem. | 278 | 35592 | 12826672 |
| 1HQO | The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. | Umland, T.C., Taylor, K.L., Rhee, S., Wickner, R.B., Davies, D.R. | 2001 | Proc.Natl.Acad.Sci.USA | 98 | 1459 | 11171973 |
| 1I17 | Two different neurodegenerative diseases caused by proteins with similar structures. | Mo, H., Moore, R.C., Cohen, F.E., Westaway, D., Prusiner, S.B., Wright, P.E., Dyson, H.J. | 2001 | Proc.Natl.Acad.Sci.USA | 98 | 2352 | 11226243 |
| 1I4M | Crystal structure of the human prion protein reveals a mechanism for oligomerization. | Knaus, K.J., Morillas, M., Swietnicki, W., Malone, M., Surewicz, W.K., Yee, V.C. | 2001 | Nat.Struct.Biol. | 8 | 770 | 11524679 |
| 1JZR | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | Bousset, L., Belrhali, H., Melki, R., Morera, S. | 2001 | Biochemistry | 40 | 13564 | 11695904 |
| 1K0A | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | Bousset, L., Belrhali, H., Melki, R., Morera, S. | 2001 | Biochemistry | 40 | 13564 | 11695904 |
| 1K0B | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | Bousset, L., Belrhali, H., Melki, R., Morera, S. | 2001 | Biochemistry | 40 | 13564 | 11695904 |
| 1K0C | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | Bousset, L., Belrhali, H., Melki, R., Morera, S. | 2001 | Biochemistry | 40 | 13564 | 11695904 |
| 1K0D | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | Bousset, L., Belrhali, H., Melki, R., Morera, S. | 2001 | Biochemistry | 40 | 13564 | 11695904 |
| 1LG4 | NMR Structure of the Human Doppel Protein | Luhrs, T., Riek, R., Guntert, P., Wuthrich, K. | 2003 | J.Mol.Biol. | 326 | 1549 | 12595265 |
| 1M25 | Possible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein | Megy, S., Bertho, G., Kozin, S.A., Debey, P., Hoa, G.H., Girault, J.-P. | 2004 | Protein Sci. | 13 | 3151 | 15537751 |
| 1OEH | The octapeptide repeats in mammalian prion protein constitute a pH-dependent folding and aggregation site. | Zahn, R. | 2003 | J.Mol.Biol. | 334 | 477 | 14623188 |
| 1OEI | The octapeptide repeats in mammalian prion protein constitute a pH-dependent folding and aggregation site. | Zahn, R. | 2003 | J.Mol.Biol. | 334 | 477 | 14623188 |
| 1QLX | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1QLZ | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1QM0 | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1QM1 | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1QM2 | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1QM3 | NMR solution structure of the human prion protein. | Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Lopez Garcia, F., Billeter, M., Calzolai, L., Wider, G., Wuthrich, K. | 2000 | Proc.Natl.Acad.Sci.USA | 97 | 145 | 10618385 |
| 1S4T | Specific recognition between surface loop 2 (132-143) and helix 1 (144-154) within sheep prion protein from in vitro studies of synthetic peptides | Kozin, S.A., Lepage, C., Hui Bon Hoa, G., Rabesona, H., Mazur, A.K., Blond, A., Cheminant, M., Haertle, T., Debey, P., Rebuffat, S. | n/a | To be Published | n/a | n/a | n/a |
| 1SKH | NMR solution structure and membrane interaction of the N-terminal sequence (1-30) of the bovine prion protein. | Biverstahl, H., Andersson, A., Graslund, A., Maler, L. | 2004 | Biochemistry | 43 | 14940 | 15554701 |
| 1TPX | Insight into the PrPC -> PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants. | Eghiaian, F., Grosclaude, J., Lesceu, S., Debey, P., Doublet, B., Treguer, E., Rezaei, H., Knossow, M. | 2004 | Proc.Natl.Acad.Sci.USA | 101 | 10254 | 15240887 |
| 1TQB | Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants | Eghiaian, F., Grosclaude, J., Lesceu, S., Debey, P., Doublet, B., Treguer, E., Rezaei, H., Knossow, M. | 2004 | Proc.Natl.Acad.Sci.USA | 101 | 10254 | 15240887 |
| 1TQC | Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants | Eghiaian, F., Grosclaude, J., Lesceu, S., Debey, P., Doublet, B., Treguer, E., Rezaei, H., Knossow, M. | 2004 | Proc.Natl.Acad.Sci.USA | 101 | 10254 | 15240887 |
| 1U3M | Prion protein NMR structures of chickens, turtles, and frogs | Calzolai, L., Lysek, D.A., Perez, D.R., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.Usa | 102 | 651 | 15647366 |
| 1U5L | Prion protein NMR structures of chicken, turtle, and frog | Calzolai, L., Lysek, D.A., Perez, D.R., Guntert, P., Wuthrich, K. | 2005 | PROC.NATL.ACAD.SCI.USA | 102 | 651 | 15647366 |
| 1UW3 | The crystal structure of the globular domain of sheep prion protein. | Haire, L.F., Whyte, S.M., Vasisht, N., Gill, A.C., Verma, C., Dodson, E.J., Dodson, G.G., Bayley, P.M. | 2004 | J.Mol.Biol. | 336 | 1175 | 15037077 |
| 1XU0 | Prion protein NMR structures of chicken, turtle, and frog | Calzolai, L., Lysek, D.A., Perez, D.R., Guntert, P., Wuthrich, K. | 2005 | PROC.NATL.ACAD.SCI.USA | 102 | 651 | 15647366 |
| 1XYJ | Prion protein NMR structures of cats, dogs, pigs, and sheep | Lysek, D.A., Schorn, C., Nivon, L.G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.USA | 102 | 640 | 15647367 |
| 1XYK | Prion protein NMR structures of cats, dogs, pigs, and sheep | Lysek, D.A., Schorn, C., Nivon, L.G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.USA | 102 | 640 | 15647367 |
| 1XYQ | Prion protein NMR structures of cats, dogs, pigs, and sheep | Lysek, D.A., Schorn, C., Nivon, L.G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.Usa | 102 | 640 | 15647367 |
| 1XYU | Prion protein NMR structures of cats, dogs, pigs, and sheep | Lysek, D.A., Schorn, C., Nivon, L.G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.USA | 102 | 640 | 15647367 |
| 1XYW | Prion protein NMR structures of elk and of mouse/elk hybrids | Gossert, A.D., Bonjour, S., Lysek, D.A., Fiorito, F., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.Usa | 102 | 646 | 15647363 |
| 1XYX | Prion protein NMR structures of elk and of mouse/elk hybrids | Gossert, A.D., Bonjour, S., Lysek, D.A., Fiorito, F., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.USA | 102 | 646 | 15647363 |
| 1Y15 | Prion protein NMR structures of elk and of mouse/elk hybrids | Gossert, A.D., Bonjour, S., Lysek, D.A., Fiorito, F., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.Usa | 102 | 646 | 15647363 |
| 1Y16 | Prion protein NMR structures of elk and of mouse/elk hybrids | Gossert, A.D., Bonjour, S., Lysek, D.A., Fiorito, F., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.Usa | 102 | 646 | 15647363 |
| 1Y2S | Prion protein NMR structures of cats, dogs, pigs, and sheep | Lysek, D.A., Schorn, C., Nivon, L.G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. | 2005 | Proc.Natl.Acad.Sci.USA | 102 | 640 | 15647367 |
| 1YJO | Structure of the cross-beta spine of amyloid-like fibrils. | Nelson, R., Sawaya, M.R., Balbirnie, M., Madsen, A.O., Riekel, C., Grothe, R., Eisenberg, D. | 2005 | Nature | 435 | 773 | 15944695 |
| 1YJP | Structure of the cross-beta spine of amyloid-like fibrils. | Nelson, R., Sawaya, M.R., Balbirnie, M., Madsen, A.O., Riekel, C., Grothe, R., Eisenberg, D. | 2005 | Nature | 435 | 773 | 15944695 |
| 1Z65 | NMR Solution Structure of the Peptide Fragment 1-30, Derived from Unprocessed Mouse Doppel Protein, in DHPC Micelles | Papadopoulos, E., Oglecka, K., Maler, L., Jarvet, J., Wright, P.E., Dyson, H.J., Graslund, A. | 2006 | Biochemistry | 45 | 159 | 16388591 |
| 2FJ3 | NMR solution of rabbit Prion Protein (91-228) | Li, J., Mei, F.H., Xiao, G.F., Lin, D.H. | n/a | To be published | n/a | n/a | n/a |
| 2HH0 | Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation | Luginbuhl, B., Kanyo, Z., Jones, R.M., Fletterick, R.J., Prusiner, S.B., Cohen, F.E., Williamson, R.A., Burton, D.R., Pluckthun, A. | 2006 | J.Mol.Biol. | 363 | 75 | 16962610 |
| 2IV4 | The Conformational Landscape of the Human Prion Protein Alpha 2 Domain: Comparative NMR and Md Studies on Helix-2-Derived Peptides | Ronga, L., Palladino, P., Tizzano, B., Costantini, S., Facchiano, A., Saviano, G., Tancredi, T., Ruvo, M., Ragone, R., Benedetti, E., Rossi, F. | n/a | To be Published | n/a | n/a | n/a |
| 2IV5 | The Conformational Landscape of the Human Prion Protein Alpha 2 Domain: Comparative NMR and Md Studies on Helix-2-Derived Peptides | Ronga, L., Palladino, P., Tizzano, B., Costantini, S., Facchiano, A., Saviano, G., Tancredi, T., Ruvo, M., Ragone, R., Benedetti, E., Rossi, F. | n/a | To be Published | n/a | n/a | n/a |
| 2IV6 | The Conformational Landscape of the Human Prion Protein Alpha 2 Domain: Comparative NMR and Md Studies on Helix-2-Derived Peptides | Ronga, L., Palladino, P., Tizzano, B., Costantini, S., Facchiano, A., Saviano, G., Tancredi, T., Ruvo, M., Ragone, R., Benedetti, E., Rossi, F. | n/a | To be Published | n/a | n/a | n/a |
| 2JOH | 1H, 13C and 15N resonance assignments of rabbit prion protein (91-228) | Li, J., Mei, F.H., Xiao, G.F., Guo, C.Y., Lin, D.H. | 2007 | J.Biomol.Nmr | 38 | 181 | 17415669 |
| 2JOM | 1H, 13C and 15N resonance assignments of rabbit prion protein (91-228) | Li, J., Mei, F.H., Xiao, G.F., Guo, C.Y., Lin, D.H. | 2007 | J.Biomol.Nmr | 38 | 181 | 17415669 |
| 2OL9 | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. | Sawaya, M.R., Sambashivan, S., Nelson, R., Ivanova, M.I., Sievers, S.A., Apostol, M.I., Thompson, M.J., Balbirnie, M., Wiltzius, J.J., McFarlane, H.T., Madsen, A.O., Riekel, C., Eisenberg, D. | 2007 | Nature | 447 | 453 | 17468747 |
| 2OLX | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. | Sawaya, M.R., Sambashivan, S., Nelson, R., Ivanova, M.I., Sievers, S.A., Apostol, M.I., Thompson, M.J., Balbirnie, M., Wiltzius, J.J., McFarlane, H.T., Madsen, A.O., Riekel, C., Eisenberg, D. | 2007 | Nature | 447 | 453 | 17468747 |
| 2OMM | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. | Sawaya, M.R., Sambashivan, S., Nelson, R., Ivanova, M.I., Sievers, S.A., Apostol, M.I., Thompson, M.J., Balbirnie, M., Wiltzius, J.J., McFarlane, H.T., Madsen, A.O., Riekel, C., Eisenberg, D. | 2007 | Nature | 447 | 453 | 17468747 |
| 2ONX | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. | Sawaya, M.R., Sambashivan, S., Nelson, R., Ivanova, M.I., Sievers, S.A., Apostol, M.I., Thompson, M.J., Balbirnie, M., Wiltzius, J.J., McFarlane, H.T., Madsen, A.O., Riekel, C., Eisenberg, D. | 2007 | Nature | 447 | 453 | 17468747 |
| 2RMV | Key role of the residue 155 in the mechanism of prion transconformation highlighted by the study of sheep mutant peptides | Bertho, G., Bouvier, G., Hui Bon Hoa, G., Girault, J.-P. | n/a | To be Published | n/a | n/a | n/a |
| 2RMW | Key role of the residue 155 in the mechanism of prion transconformation highlighted by the study of sheep mutant peptides | Bertho, G., Bouvier, G., Hui Bon Hoa, G., Girault, J.-P. | n/a | To be Published | n/a | n/a | n/a |
| 2RNM | Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core | Wasmer, C., Lange, A., Van Melckebeke, H., Siemer, A.B., Riek, R., Meier, B.H. | 2008 | Science | 319 | 1523 | 18339938 |
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