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Fatty Acid Synthase

A list of 'fatty acid synthase' related entries in the PDB

as determined by a keyword search on June 01, 2007
Structure ID  Title Authors Publication Year Journal Name Volume ID First Page Pubmed
1ACP Refinement of the NMR structures for acyl carrier protein with scalar coupling data. Kim, Y., Prestegard, J.H. 1990 Proteins 8 377 2091027
1B3N Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. Moche, M., Schneider, G., Edwards, P., Dehesh, K., Lindqvist, Y. 1999 J.Biol.Chem. 274 6031 10037680
1DD8 The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I. Olsen, J.G., Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M., Lindquist, Y., Larsen, S. 1999 FEBS Lett. 460 46 10571059
1DV5 Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier protein. Volkman, B.F., Zhang, Q., Debabov, D.V., Rivera, E., Kresheck, G.C., Neuhaus, F.C. 2001 Biochemistry 40 7964 11434765
1EBL The erichia Davies, C., Heath, R.J., White, S.W., Rock, C.O. 2000 Structure Fold.Des. 8 185 10673437
1EK4 Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Olsen, J.G., Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M., Larsen, S. 2001 Structure 9 233 11286890
1F7L Crystal carrier es Parris, K.D., Lin, L., Tam, A., Mathew, R., Hixon, J., Stahl, M., Fritz, C.C., Seehra, J., Somers, W.S. 2000 Structure Fold.Des. 8 883 10997907
1F7T Crystal carrier es Parris, K.D., Lin, L., Tam, A., Mathew, R., Hixon, J., Stahl, M., Fritz, C.C., Seehra, J., Somers, W.S. 2000 Structure Fold.Des. 8 883 10997907
1F80 Crystal carrier es Parris, K.D., Lin, L., Tam, A., Mathew, R., Hixon, J., Stahl, M., Fritz, C.C., Seehra, J., Somers, W.S. 2000 Structure Fold.Des. 8 883 10997907
1F91 Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Olsen, J.G., Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M., Larsen, S. 2001 Structure 9 233 11286890
1FE2 Mutational -gamma > Thuresson, E.D., Malkowski, M.G., Lakkides, K.M., Rieke, C.J., Mulichak, A.M., Ginell, S.L., Garavito, R.M., Smith, W.L. 2001 J.Biol.Chem. 276 10358 11121413
1FJ4 Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. Price, A.C., Choi, K.H., Heath, R.J., Li, Z., White, S.W., Rock, C.O. 2001 J.Biol.Chem. 276 6551 11050088
1FJ8 Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. Price, A.C., Choi, K.H., Heath, R.J., Li, Z., White, S.W., Rock, C.O. 2001 J.Biol.Chem. 276 6551 11050088
1FTE Crystal ase: an Chirgadze, N.Y., Briggs, S.L., McAllister, K.A., Fischl, A.S., Zhao, G. 2000 EMBO J. 19 5281 11032795
1FTF Crystal ase: an Chirgadze, N.Y., Briggs, S.L., McAllister, K.A., Fischl, A.S., Zhao, G. 2000 EMBO J. 19 5281 11032795
1FTH Crystal ase: an Chirgadze, N.Y., Briggs, S.L., McAllister, K.A., Fischl, A.S., Zhao, G. 2000 EMBO J. 19 5281 11032795
1G5X Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III. Zhang, Y.M., Rao, M.S., Heath, R.J., Price, A.C., Olson, A.J., Rock, C.O., White, S.W. 2001 J.Biol.Chem. 276 8231 11078736
1H4F Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
1HN9 Crystal key Qiu, ., > 1999 J.Biol.Chem. 274 36465 10593943
1HND Refined structures of beta-ketoacyl-acyl carrier protein synthase III. Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K. 2001 J.Mol.Biol. 307 341 11243824
1HNH Refined structures of beta-ketoacyl-acyl carrier protein synthase III. Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K. 2001 J.Mol.Biol. 307 341 11243824
1HNJ Refined structures of beta-ketoacyl-acyl carrier protein synthase III. Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K. 2001 J.Mol.Biol. 307 341 11243824
1HNK Refined structures of beta-ketoacyl-acyl carrier protein synthase III. Qiu, X., Janson, C.A., Smith, W.W., Head, M., Lonsdale, J., Konstantinidis, A.K. 2001 J.Mol.Biol. 307 341 11243824
1HQB Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier protein. Volkman, B.F., Zhang, Q., Debabov, D.V., Rivera, E., Kresheck, G.C., Neuhaus, F.C. 2001 Biochemistry 40 7964 11434765
1HZP Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III Scarsdale, J.N., Kazanina, G., He, X., Reynolds, K.A., Wright, H.T. 2001 J.Biol.Chem. 276 20516 11278743
1IGX Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. Malkowski, M.G., Thuresson, E.D., Lakkides, K.M., Rieke, C.J., Micielli, R., Smith, W.L., Garavito, R.M. 2001 J.Biol.Chem. 276 37547 11477109
1IGZ Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. Malkowski, M.G., Thuresson, E.D., Lakkides, K.M., Rieke, C.J., Micielli, R., Smith, W.L., Garavito, R.M. 2001 J.Biol.Chem. 276 37547 11477109
1J3N Crystal Structure of 3-oxoacyl-(acyl-carrier protein) Synthase II from Thermus Thermophilus Bagautdinov, B., Miyano, M., Tahirov, T.H. n/a To be published n/a n/a n/a
1KAS Crystal E.coli Huang, W., Jia, J., Edwards, P., Dehesh, K., Schneider, G., Lindqvist, Y. 1998 EMBO J. 17 1183 9482715
1KP9 Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis Huang, C.-C., Smith, C.V., Glickman, M.S., Jacobs Jr., W.R., Sacchettini, J.C. 2002 J.Biol.Chem. 277 11559 11756461
1KPG Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis Huang, C.-C., Smith, C.V., Glickman, M.S., Jacobs Jr., W.R., Sacchettini, J.C. 2002 J.Biol.Chem. 277 11559 11756461
1KPH Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis Huang, C.-C., Smith, C.V., Glickman, M.S., Jacobs Jr., W.R., Sacchettini, J.C. 2002 J.Biol.Chem. 277 11559 11756461
1KPI Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis Huang, C.-C., Smith, C.V., Glickman, M.S., Jacobs Jr., W.R., Sacchettini, J.C. 2002 J.Biol.Chem. 277 11559 11756461
1M1M X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (MTFABH) Sacchettini, J.C., Sridharan, S. n/a To be Published n/a n/a n/a
1MLA The t 1.5-A . Serre, L., Verbree, E.C., Dauter, Z., Stuitje, A.R., Derewenda, Z.S. 1995 J.Biol.Chem. 270 12961 7768883
1MZS First and a logy Daines, K., S., 2003 J.Med.Chem. 46 5 12502353
1N8L The ACP domain from type I rat FAS shows considerable structural and Reed, M.A.C., Crump, M.P., Schweizer, M., Crosby, J., Simpson, T.J. 2003 ORG.BIOMOL.CHEM. 3 463 n/a
1T8K Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions Qiu, X., Janson, C.A. 2004 Acta Crystallogr., Sect.D 60 1545 15333924
1U5U The structure of coral allene oxide synthase reveals a catalase adapted for metabolism of a fatty acid hydroperoxide. Oldham, M.L., Brash, A.R., Newcomer, M.E. 2005 Proc.Natl.Acad.Sci.USA 102 297 15625113
1U6E Crystal Musayev, F., Sachdeva, S., Scarsdale, J.N., Reynolds, K.A., Wright, H.T. 2005 J.Mol.Biol. 346 1313 15713483
1U6S Crystal Musayev, F., Sachdeva, S., Scarsdale, J.N., Reynolds, K.A., Wright, H.T. 2005 J.Mol.Biol. 346 1313 15713483
1UB7 The Crystal Structure of Beta-Ketoacyl-[Acyl Carrier Protein] Synthase III (Fabh) from Thermus Thermophilus Inagaki, E., Kuramitsu, S., Yokoyama, S., Miyano, M., Tahirov, T.H. n/a To be Published n/a n/a n/a
1W0I Structure se from Olsen, J.G., Rasmussen, A.V., Von Wettstein-Knowles, P., Henriksen, A. 2004 FEBS Lett. 577 170 n/a
1XKT Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain Chakravarty, B., Gu, Z., Chirala, S.S., Wakil, S.J., Quiocho, F.A. 2004 Proc.Natl.Acad.Sci.USA 101 15567 n/a
1ZOW Crystal rrier Qiu, X., Choudhry, A.E., Janson, C.A., Grooms, M., Daines, R.A., Lonsdale, J.T., Khandekar, S.S. 2005 Protein Sci. 14 2087 15987898
2AHB Probing Acyl IS AND Brown, A.K., Sridharan, S., Kremer, L., Lindenberg, S., Dover, L.G., Sacchettini, J.C., Besra, G.S. 2005 J.Biol.Chem. 280 32539 16040614
2AJ9 Probing yl is And Brown, A.K., Sridharan, S., Kremer, L., Lindenberg, S., Dover, L.G., Sacchettini, J.C., Besra, G.S. 2005 J.Biol.Chem. 280 32539 16040614
2ALM The Catalytic Mechanism of the Elongation Condensing Enzymes of Fatty Acid Synthases Zhang, Y.-M., Hurlbert, J.C., White, S.W., Rock, C.O. n/a To be Published n/a n/a n/a
2AQ7 Structure-Activity ng > Kim, atha, ncan, 2006 J.Med.Chem. 49 159 16392800
2AQB Structure-Activity ng > Kim, atha, ncan, 2006 J.Med.Chem. 49 159 16392800
2AYL 2.0A structure of prostaglandin H2 synthase-1 reconstituted with a manganese porphyrin cofactor Gupta, K., Selinsky, B.S., Loll, P.J. 2006 Acta Crystallogr., Sect.D 62 151 n/a
2BUH Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BUI Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BYW Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BYX Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BYY Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BYZ Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BZ3 Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2BZ4 Fatty Acid Synthesis. Von Wettstein-Knowles, P., Olsen, J.G., Mcguire, K.A., Henriksen, A. 2006 FEBS J. 273 695 n/a
2C2N Structure of Human Mitochondrial Malonyltransferase Wu, X., Bunkoczi, G., Smee, C., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Von Delft, F., Oppermann, U. n/a To be Published n/a n/a n/a
2C9H Structure of Mitochondrial Beta-Ketoacyl Synthase Bunkoczi, n/a To be Published n/a n/a n/a
2CDH Architecture of a Fungal Fatty Acid Synthase at 5 A Resolution. Jenni, S., Leibundgut, M., Maier, T., Ban, N. 2006 Science 311 1263 n/a
2CF2 Architecture of Mammalian Fas at 4.5A Resolution Maier, T., Jenni, S., Ban, N. 2006 Science 311 1258 n/a
2CG5 Structure oenzyme Bunkoczi, G., rom, n/a To be Published n/a n/a n/a
2CVD Structural Aritake, K., Kado, Y., Inoue, T., Miyano, M., Urade, Y. 2006 J.Biol.Chem. 281 15277 16547010
2CZT Structural Basis of Multi-functional Lipocalin-type Prostaglandin D Synthase Kumasaka, T., Irikura, D., Ago, H., Aritake, K., Yamamoto, M., Inoue, T., Miyano, M., Urade, Y., Hayaishi, O. n/a To be Published n/a n/a n/a
2CZU Structural Basis of Multi-functional Lipocalin-type Prostaglandin D Synthase Kumasaka, T., Irikura, D., Ago, H., Aritake, K., Yamamoto, M., Inoue, T., Miyano, M., Urade, Y., Hayaishi, O. n/a To be Published n/a n/a n/a
2FAC Structural tes. Roujeinikova, A., Simon, W.J., Gilroy, J., Rice, D.W., Rafferty, J.B., Slabas, A.R. 2007 J.Mol.Biol. 365 135 17059829
2FAD Structural tes. Roujeinikova, A., Simon, W.J., Gilroy, J., Rice, D.W., Rafferty, J.B., Slabas, A.R. 2007 J.Mol.Biol. 365 135 17059829
2FAE Structural tes. Roujeinikova, A., Simon, W.J., Gilroy, J., Rice, D.W., Rafferty, J.B., Slabas, A.R. 2007 J.Mol.Biol. 365 135 17059829
2FHS Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli. Rafi, S., Novichenok, P., Kolappan, S., Zhang, X., Stratton, C.F., Rawat, R., Kisker, C., Simmerling, C., Tonge, P.J. 2006 J.Biol.Chem. 281 39285 17012233
2FNQ Insights um t Oldham, M.L., Brash, A.R., Newcomer, M.E. 2005 J.Biol.Chem. 280 39545 16162493
2GFV Platensimycin is a selective FabF inhibitor with potent antibiotic properties Wang, , , hang, oud, ., , td> 2006 Nature 441 358 n/a
2GFW Platensimycin is a selective FabF inhibitor with potent antibiotic properties Wang, , , hang, oud, ., , td> 2006 Nature 441 358 n/a
2GFX Platensimycin is a selective FabF inhibitor with potent antibiotic properties Wang, , , hang, oud, ., , td> 2006 Nature 441 358 n/a
2GFY Platensimycin is a selective FabF inhibitor with potent antibiotic properties Wang, , , hang, oud, ., , td> 2006 Nature 441 358 n/a
2GP6 X-Ray Crystal Structure of Mycobacterium tuberculosis beta-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB). Sridharan, S., Wang, L., Brown, A.K., Dover, L.G., Kremer, L., Besra, G.S., Sacchettini, J.C. 2007 J.Mol.Biol. 366 469 17174327
2GQD The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus Miller, D.J., Zhang, Y.M., Rock, C.O., White, S.W. n/a To be Published n/a n/a n/a
2H84 Biosynthesis hybrid Austin, M.B., Saito, T., Bowman, M.E., Haydock, S., Kato, A., Moore, B.S., Kay, R.R., Noel, J.P. 2006 Nat.Chem.Biol. 2 494 16906151
2IAG Crystal Structure of the Human Prostacyclin Synthase Chiang, C.-W., Yeh, H.-C., Wang, L.-H., Chan, N.-L. 2006 J.Mol.Biol. 364 266 17020766
2IWY Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase. Christensen, C.E., Kragelund, B.B., Von Wettstein-Knowles, P., Henriksen, A. 2007 Protein Sci. 16 261 n/a
2IWZ Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase. Christensen, C.E., Kragelund, B.B., Von Wettstein-Knowles, P., Henriksen, A. 2007 Protein Sci. 16 261 n/a
2IX4 Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase. Christensen, C.E., Kragelund, B.B., Von Wettstein-Knowles, P., Henriksen, A. 2007 Protein Sci. 16 261 n/a
2JBZ Crystal Structure of the Streptomyces Coelicolor Apo- and Holo- Acyl Carrier Protein Synthase Dall'Aglio, P., Arthur, C., Law, C.K.E., Crump, M.P., Crosby, J., Hadfield, A.T. n/a To be Published n/a n/a n/a
2JCA Crystal Structure of the Streptomyces Coelicolor Apo- and Holo- Acyl Carrier Protein Synthase Dall'Aglio, P., Arthur, C., Crump, M.P., Crosby, J., Hadfield, A.T. n/a To be Published n/a n/a n/a
2JFD Structure of the MAT Domain of Human Fas Bunkoczi, A., n/a To be Published n/a n/a n/a
2JFK Structure of the MAT Domain of Human Fas with Malonyl-Coa Bunkoczi, , S., n/a To be Published n/a n/a n/a
2NM0 Structural and functional studies on SCO1815: a beta-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2). Tang, Y., Lee, H.Y., Tang, Y., Kim, C.Y., Mathews, I., Khosla, C. 2006 Biochemistry 45 14085 17115703
2UV8 Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase Leibundgut, M., Jenni, S., Frick, C., Ban, N. 2007 Science 316 288 n/a
2UV9 Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling Jenni, S., Leibundgut, M., Boehringer, D., Frick, C., Mikolasek, B., Ban, N. 2007 Science 316 254 n/a
2UVA Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling Jenni, S., Leibundgut, M., Boehringer, D., Frick, C., Mikolasek, B., Ban, N. 2007 Science 316 254 n/a
2UVB Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling Jenni, S., Leibundgut, M., Boehringer, D., Frick, C., Mikolasek, B., Ban, N. 2007 Science 316 254 n/a
2UVC Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling Jenni, S., Leibundgut, M., Boehringer, D., Frick, C., Mikolasek, B., Ban, N. 2007 Science 316 254 n/a

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Last changed by: A.Honegger, 8/6/08