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Major Histocompatibility Complex

PDB ID Authors First Page PubMed ID Journal Name Citation Title Volume No Publication Year
1HSA D.R.Madden, J.C.Gorga, J.L.Strominger, D.C.Wiley 1035 1525820 Cell The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC. 70 1992
1OGT M.Hulsmeyer, M.T.Fiorillo, F.Bettosini, R.Sorrentino, W.Saenger, A.Ziegler, B.Uchanska-Ziegler 271 n/a J.Exp.Med. Dual, Hla-B27 Subtype-Dependent Conformation of a Self-Peptide 199 2004
1JGE M.Hulsmeyer, R.C.Hillig, A.Volz, M.Ruhl, W.Schroder, W.Saenger, A.Ziegler, B.Uchanska-Ziegler 47844 12244049 J.Biol.Chem. Hla-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations 277 2002
1UXS M.T.Fiorillo, C.Ruckert, M.Hulsmeyer, R.Sorrentino, W.Saenger, A.Ziegler, B.Uchanska-Ziegler n/a n/a To be Published Allele-Dependent Similarity between Viral and Self-Peptide Presentation by Hla-B27 Subtypes n/a n/a
1UXW M.T.Fiorillo, C.Ruckert, M.Hulsmeyer, R.Sorrentino, W.Saenger, A.Ziegler, B.Uchanska-Ziegler n/a n/a To be Published Allele-Dependent Similarity between Viral and Self-Peptide Presentation by Hla-B27 Subtypes n/a n/a
1OF2 M.Hulsmeyer, M.T.Fiorillo, F.Bettosini, R.Sorrentino, W.Saenger, A.Ziegler, B.Uchanska-Ziegler 271 n/a J.Exp.Med. Dual, Hla-B27 Subtype-Dependent Conformation of a Self-Peptide 199 2004
1JGD R.C.Hillig, M.Huelsmeyer, W.Saenger, K.Welfle, R.Misselwitz, H.Welfle, Kozerski C., A.Volz, B.Uchanska-Ziegler, A.Ziegler 652 14555655 J.Biol.Chem. Thermodynamic and Structural Analysis of Peptide-and Allele-Dependent Properties of Two Hla-B27 Subtypes Exhibiting Differential Disease Association 279 2004
1K5N M.Hulsmeyer, R.C.Hillig, A.Volz, M.Ruhl, W.Schroder, W.Saenger, A.Ziegler, B.Uchanska-Ziegler 47844 12244049 J.Biol.Chem. Hla-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations 277 2002
1SYS D.Zernich, A.W.Purcell, W.A.Macdonald, L.Kjer-Nielsen, L.K.Ely, N.Laham, T.Crockford, N.A.Mifsud, M.Bharadwaj, L.Chang, B.D.Tait, R.Holdsworth, A.G.Brooks, S.P.Bottomley, T.Beddoe, C.A.Peh, J.Rossjohn, J.Mccluskey 13 15226359 J.Exp.Med. Natural Hla Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion 200 2004
1N2R W.A.Macdonald, A.W.Purcell, N.A.Mifsud, L.K.Ely, D.S.Williams, L.Chang, J.J.Gorman, C.S.Clements, L.Kjer-Nielsen, D.M.Koelle, S.R.Burrows, B.D.Tait, R.Holdsworth, A.G.Brooks, G.O.Lovrecz, L.Lu, J.Rossjohn, J.Mccluskey 679 12939341 J.Exp.Med. A Naturally Selected Dimorphism within the Hla-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition. 198 2003
1M6O W.Macdonald, A.W.Purcell, D.S.Williams, N.Mifsud, L.K.Ely, J.J.Gorman, C.S.Clements, L.Kjer-Nielsen, D.M.Koelle, A.G.Brooks, G.O.Lovrecz, L.Lu, J.Rossjohn, J.Mccluskey n/a n/a To be Published Hla Class I Micropolymorphism Fine Tunes Peptide Reportoire But Dramatically Alters Functional Recognition. n/a n/a
1AGD S.W.Reid, S.McAdam, K.J.Smith, P.Klenerman, C.A.O'Callaghan, K.Harlos, B.K.Jakobsen, A.J.McMichael, J.I.Bell, D.I.Stuart, E.Y.Jones 2279 8976183 J Exp Med Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. 184 1996
1AGF S.W.Reid, S.McAdam, K.J.Smith, P.Klenerman, C.A.O'Callaghan, K.Harlos, B.K.Jakobsen, A.J.McMichael, J.I.Bell, D.I.Stuart, E.Y.Jones 2279 8976183 J Exp Med Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. 184 1996
1AGE S.W.Reid, S.McAdam, K.J.Smith, P.Klenerman, C.A.O'Callaghan, K.Harlos, B.K.Jakobsen, A.J.McMichael, J.I.Bell, D.I.Stuart, E.Y.Jones 2279 8976183 J Exp Med Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. 184 1996
1AGC S.W.Reid, S.McAdam, K.J.Smith, P.Klenerman, C.A.O'Callaghan, K.Harlos, B.K.Jakobsen, A.J.McMichael, J.I.Bell, D.I.Stuart, E.Y.Jones 2279 8976183 J Exp Med Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. 184 1996
1AGB S.W.Reid, S.McAdam, K.J.Smith, P.Klenerman, C.A.O'Callaghan, K.Harlos, B.K.Jakobsen, A.J.McMichael, J.I.Bell, D.I.Stuart, E.Y.Jones 2279 8976183 J Exp Med Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. 184 1996
1M05 L.Kjer-Nielsen, C.S.Clements, A.G.Brooks, A.W.Purcell, M.R.Fontes, J.Mccluskey, J.Rossjohn 5153 12391232 J.Immunol. The Structure of Hla-B8 Complexed to an Immunodominant Viral Determinant: Peptide-Induced Conformational Changes and a Mode of Mhc Class I Dimerization. 169 2003
1MI5 L.Kjer-Nielsen, C.S.Clements, A.W.Purcell, A.G.Brooks, J.C.Whisstock, S.R.Burrows, J.Mccluskey, J.Rossjohn 53 12530975 Immunity A Structural Basis for the Selection of Dominant Alphabeta T Cell Receptors in Antiviral Immunity 18 2003
1SYV D.Zernich, A.W.Purcell, W.A.Macdonald, L.Kjer-Nielsen, L.K.Ely, N.Laham, T.Crockford, N.A.Mifsud, M.Bharadwaj, L.Chang, B.D.Tait, R.Holdsworth, A.G.Brooks, S.P.Bottomley, T.Beddoe, C.A.Peh, J.Rossjohn, J.Mccluskey 13 15226359 J.Exp.Med. Natural Hla Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion 200 2004
1A1O K.J.Smith, S.W.Reid, K.Harlos, A.J.McMichael, D.I.Stuart, J.I.Bell, E.Y.Jones 215 8624812 Immunity Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. 4 1996
1A1M K.J.Smith, S.W.Reid, K.Harlos, A.J.McMichael, D.I.Stuart, J.I.Bell, E.Y.Jones 215 8624812 Immunity Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. 4 1996
1E27 K.Maenaka, T.Maenaka, H.Tomiyama, M.Takiguchi, D.I.Stuart, E.Y.Jones 3260 10975842 J.Immunol. Nonstandard Peptide Binding Revealed by Crystal Structures of Hla-B5101 Complexed with HIV Immunodominant Epitopes 165 2000
1XH3 M.Probst-Kepper, H.J.Hecht, H.Herrmann, V.Janke, F.Ocklenburg, J.Klempnauer, B.J.Van Den Eynde, S.Weiss 5610 15494511 J.Immunol. Conformational Restraints and Flexibility of 14-Meric Peptides in Complex with Hla-B3501. 173 2004
1A9B R.Menssen, P.Orth, A.Ziegler, W.Saenger 645 9878435 J Mol Biol Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus. 285 1999
1A9E R.Menssen, P.Orth, A.Ziegler, W.Saenger 645 9878435 J Mol Biol Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus. 285 1999
1E28 K.Maenaka, T.Maenaka, H.Tomiyama, M.Takiguchi, D.I.Stuart, E.Y.Jones 3260 10975842 J.Immunol. Nonstandard Peptide Binding Revealed by Crystal Structures of Hla-B5101 Complexed with HIV Immunodominant Epitopes 165 2000
1A1N K.J.Smith, S.W.Reid, D.I.Stuart, A.J.McMichael, E.Y.Jones, J.I.Bell 203 8624811 Immunity An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. 4 1996
1CG9 R.Menssen, P.Orth, A.Ziegler, W.Saenger n/a n/a To be Published Complex Recognition of the Supertypic Bw6-Determinant on Hla-B and-C Molecules by the Monoclonal Antibody Sfr8-B6 n/a n/a
1QVO L.Li, M.Bouvier 6175 15128805 J.Immunol. Structures of Hla-A1101 Complexed with Immunodominant Nonamer and Decamer HIV-1 Epitopes Clearly Reveal the Presence of a Middle, Secondary Anchor Residue. 172 2004
1Q94 L.Li, M.Bouvier 6175 15128805 J.Immunol. Structures of Hla-A1101 Complexed with Immunodominant Nonamer and Decamer HIV-1 Epitopes Clearly Reveal the Presence of a Middle, Secondary Anchor Residue. 172 2004
1EFX J.C.Boyington, S.A.Motyka, P.Schuck, A.G.Brooks, P.D.Sun 537 10850706 Nature Crystal Structure of an Nk Cell Immunoglobulin-Like Receptor in Complex with its Class I Mhc Ligand. 405 2000
1IM9 Q.R.Fan, E.O.Long, D.C.Wiley 452 11323700 Nat.Immunol. Crystal Structure of the Human Natural Killer Cell Inhibitory Receptor Kir2Dl1 Bound to its Mhc Ligand Hla-Cw4 2 2001
1QQD Q.R.Fan, D.C.Wiley 1 10429675 J. Exp. Med. Structure of Hla-Cw4, a Ligand for the Kir2D Natural Killer Cell Inhibitory Receptor 190 1999
1W72 M.Hulsmeyer, P.Chames, R.C.Hillig, R.L.Stanfield, G.Held, P.G.Coulie, C.Alings, G.Wille, W.Saenger, B.Uchanska-Ziegler, H.R.Hoogenboom, A.Ziegler n/a n/a J.Biol.Chem. An Mhc:Peptide-Restricted Antibody and Tcr Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Hla-A1:Mage-A1 in Complex with Fab-Hyb3 n/a 2004
1OGA G.B.E.Stewart-Jones, A.J.Mcmichael, J.I.Bell, D.I.Stuart, E.Y.Jones 657 n/a Nat.Immunol. A Structural Basis for Immunodominant Human T Cell Receptor Recognition 4 2003
1AKJ G.F.Gao, J.Tormo, U.C.Gerth, J.R.Wyer, A.J.McMichael, D.I.Stuart, J.I.Bell, E.Y.Jones, B.K.Jakobsen 630 9177355 Nature Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. 387 1997
1P7Q B.E.Willcox, L.M.Thomas, P.J.Bjorkman 913 12897781 Nat.Immunol. Crystal Structure of Hla-A2 Bound to Lir-1, a Host and Viral Major Histocompatibility Complex Receptor. 4 2003
1I1Y T.J.Kirksey, R.R.Pogue-Caley, J.A.Frelinger, E.J.Collins 37259 10601290 J.Biol.Chem. The Structural Basis for the Increased Immunogenicity of Two HIV-Reverse Transcriptase Peptide Variant/Class I Major Histocompatibility Complexes 274 1999
1HHI D.R.Madden, D.N.Garboczi, D.C.Wiley 693 7694806 Cell The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. 75 1993
1I7U J.Busslep, R.Zhao, D.Donnini, D.Loftus, M.Saad, E.Appella, E.J.Collins n/a n/a To be Published T Cell Activity Correlates with Oligomeric Peptide/Mhc Binding on T Cell Surface n/a n/a
1I1F T.J.Kirksey, R.R.Pogue-Caley, J.A.Frelinger, E.J.Collins 37259 10601290 J.Biol.Chem. The Structural Basis for the Increased Immunogenicity of Two HIV-Reverse Transcriptase Peptide Variant/Class I Major Histocompatibility Complexes 274 1999
1QR1 J. J.Kuhns, M. A.Batalia, S.Yan, E. J.Collins 36422 10593938 J.Biol.Chem. Poor Binding of a Her-2/Neu Epitope (Gp2) to Hla-A2.1 Is due to a Lack of Interactions with the Center of the Peptide 274 1999
1I7T J.Busslep, R.Zhao, D.Donnini, D.Loftus, M.Saad, E.Appella, E.J.Collins n/a n/a To be Published T Cell Activity Correlates with Oligomeric Peptide/Mhc Binding on T Cell Surface n/a n/a
1HHG D.R.Madden, D.N.Garboczi, D.C.Wiley 693 7694806 Cell The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. 75 1993
1JHT P.Sliz, O.Michielin, J.C.Cerottini, I.Luescher, P.Romero, M.Karplus, D.C.Wiley 3276 11544315 J.Immunol. Crystal Structures of Two Closely Related But Antigenically Distinct Hla-A2/Melanocyte-Melanoma Tumor-Antigen Peptide Complexes 167 2001
1LP9 J.Buslepp, H.Wang, W.E.Biddison, E.Appella, E.J.Collins 595 14563323 Immunity A Correlation between Tcr Valpha Docking on Mhc and Cd8 Dependence: Implications for T Cell Selection. 19 2003
1I4F R.C.Hillig, P.G.Coulie, V.Stroobant, W.Saenger, A.Ziegler, M.Huelsmeyer 1167 11502003 J.Mol.Biol. High Resolution Structure of Hla-A0201 in Complex with a Tumor-Specific Antigenic Peptide Encoded by the Mage-A4 Gene 310 2001
1DUY A.R.Khan, B.M.Baker, P.Ghosh, W.E.Biddison, D.C.Wiley 6398 10843695 J.Immunol. The Structure and Stability of an Hla-A0201/Octameric Tax Peptide Complex with an Empty Conserved Peptide-N-Terminal Binding Site 164 2000
1IM3 B.E.Gewurz, R.Gaudet, D.Tortorella, E.W.Wang, H.L.Ploegh, D.C.Wiley 6794 11391001 Proc.Nat.Acad.Sci.USA Antigen Presentation Subverted: Structure of the Human Cytomegalovirus Protein Us2 Bound to the Class I Molecule Hla-A2 98 2001
1HHK D.R.Madden, D.N.Garboczi, D.C.Wiley 693 7694806 Cell The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. 75 1993
1B0G R.Zhao, D.J.Loftus, E.Appella, E.J.Collins 359 9892618 J Exp Med Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry. 189 1999
1HHH D.R.Madden, D.N.Garboczi, D.C.Wiley 693 7694806 Cell The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. 75 1993
2CLR E.J.Collins, D.N.Garboczi, D.C.Wiley 626 7935798 Nature Three-dimensional structure of a peptide extending from one end of a class I MHC binding site. 371 1994
1EEZ A.K.Sharma, J.J.Kuhns, E.J.Collins n/a n/a To be Published Substitution of Anchor Residues Alters Conformation of Residues at the Center of Her-2/Neu Epitope (Gp2) Complexed to Hla-A2.1 n/a n/a
1DUZ A.R.Khan, B.M.Baker, P.Ghosh, W.E.Biddison, D.C.Wiley 6398 10843695 J.Immunol. The Structure and Stability of an Hla-A0201/Octameric Tax Peptide Complex with an Empty Conserved Peptide-N-Terminal Binding Site 164 2000
1BD2 Y.H.Ding, K.J.Smith, D.N.Garboczi, U.Utz, W.E.Biddison, D.C.Wiley 403 9586631 Immunity Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. 8 1998
1EEY A.K.Sharma, J.J.Kuhns, E.J.Collins n/a n/a To be Published Substitution of Anchor Residues Alters Conformation of Residues at the Center of Her-2/Neu Epitope (Gp2) Complexed to Hla-A2.1 n/a n/a
1AO7 D.N.Garboczi, P.Ghosh, U.Utz, Q.R.Fan, W.E.Biddison, D.C.Wiley 134 8906788 Nature Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. 384 1996
1HHJ D.R.Madden, D.N.Garboczi, D.C.Wiley 693 7694806 Cell The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. 75 1993
1QEW P.Orth, C.Alings, W.Saenger, A.Ziegler n/a n/a To be Published Human Class I Histocompatibility Antigen (Hla-A 0201) Complex with a Nonameric Peptide from Melanoma-Associated Antigen 3 (Residues 271-279) n/a n/a
1B0R M.Bouvier, H.C.Guo, K.J.Smith, D.C.Wiley 97 9741848 Proteins Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group. 33 1998
1JF1 P.Sliz, O.Michielin, J.C.Cerottini, I.Luescher, P.Romero, M.Karplus, D.C.Wiley 3276 11544315 J.Immunol. Crystal Structures of Two Closely Related But Antigenically Distinct Hla-A2/Melanocyte-Melanoma Tumor-Antigen Peptide Complexes 167 2001
1I7R J.Busslep, R.Zhao, D.Donnini, D.Loftus, M.Saad, E.Appella, E.J.Collins n/a n/a To be Published T Cell Activity Correlates with Oligomeric Peptide/Mhc Binding on T Cell Surface n/a n/a
1S9Y A.I.Webb, M.A.Dunstone, W.Chen, M.I.Aguilar, Q.Chen, H.Jackson, L.Chang, L.Kjer-Nielsen, T.Beddoe, J.Mccluskey, J.Rossjohn, A.W.Purcell 23438 15004033 J.Biol.Chem. Functional and Structural Characteristics of NY-Eso-1-Related Hla A2-Restricted Epitopes and the Design of a Novel Immunogenic Analogue 279 2004
1QRN Y.H.Ding, B.M.Baker, D.N.Garboczi, W.E.Biddison, D.C.Wiley 45 10435578 Immunity Four A6-Tcr/Peptide/Hla-A2 Structures that Generate Very Different T Cell Signals are Nearly Identical 11 1999
1QSE Y. H.Ding, B. M.Baker, D. N.Garboczi, W. E.Biddison, D. C.Wiley 45 10435578 Immunity Four A6-Tcr/Peptide/Hla-A2 Structures that Generate Very Different T Cell Signals are Nearly Identical 11 1999
1S9W A.I.Webb, M.A.Dunstone, W.Chen, M.I.Aguilar, Q.Chen, H.Jackson, L.Chang, L.Kjer-Nielsen, T.Beddoe, J.Mccluskey, J.Rossjohn, A.W.Purcell 23438 15004033 J.Biol.Chem. Functional and Structural Characteristics of NY-Eso-1-Related Hla A2-Restricted Epitopes and the Design of a Novel Immunogenic Analogue 279 2004
1S9X A.I.Webb, M.A.Dunstone, W.Chen, M.I.Aguilar, Q.Chen, H.Jackson, L.Chang, L.Kjer-Nielsen, T.Beddoe, J.Mccluskey, J.Rossjohn, A.W.Purcell 23438 15004033 J.Biol.Chem. Functional and Structural Characteristics of NY-Eso-1-Related Hla A2-Restricted Epitopes and the Design of a Novel Immunogenic Analogue 279 2004
1QSF Y. H.Ding, B. M.Baker, D. N.Garboczi, W. E.Biddison, D. C.Wiley 45 10435578 Immunity Four A6-Tcr/Peptide/Hla-A2 Structures that Generate Very Different T Cell Signals are Nearly Identical 11 1999
1HSB H.C.Guo, T.S.Jardetzky, T.P.Garrett, W.S.Lane, J.L.Strominger, D.C.Wiley 364 1448153 Nature Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. 360 1992
2HLA T.P.Garrett, M.A.Saper, P.J.Bjorkman, J.L.Strominger, D.C.Wiley 692 2594067 Nature Specificity pockets for the side chains of peptide antigens in HLA-Aw68. 342 1989
3HLA M.A.Saper, P.J.Bjorkman, D.C.Wiley n/a n/a To be Published n/a n/a n/a
1HLA P.J.Bjorkman, M.A.Saper, B.Samraoui, W.S.Bennett, J.L.Strominger, D.C.Wiley 506 3309677 Nature Structure of the human class I histocompatibility antigen, HLA-A2. 329 1987
1KPR R.K.Strong, M.A.Holmes, P.Li, L.Braun-Jones, N.Lee, D.E.Geraghty 5082 12411439 J.Biol.Chem. Hla-E Allelic Variants: Correlating Differential Expression, Peptide Affinities, Crystal Structures and Thermal Stabilities 278 2003
1KTL R.K.Strong, M.A.Holmes, P.Li, L.Braun-Jones, N.Lee, D.E.Geraghty 5082 12411439 J.Biol.Chem. Hla-E Allelic Variants: Correlating Differential Expression, Peptide Affinities, Crystal Structures and Thermal Stabilities 278 2003
1MHE C.A.O'Callaghan, J.Tormo, B.E.Willcox, V.M.Braud, B.K.Jakobsen, D.I.Stuart, A.J.McMichael, J.I.Bell, E.Y.Jones 531 9660937 Mol Cell Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. 1 1998
1KJM M.G.Rudolph, J.Stevens, J.A.Speir, J.Trowsdale, G.W.Butcher, E.Joly, I.A.Wilson 975 12470953 J.Mol.Biol. Crystal Structures of Two Rat Mhc Class Ia (RT1-A) Molecules that are Associated Differentially with Peptide Transporter Alleles Tap-A and Tap-B. 324 2002
1ED3 J.A.Speir, J.Stevens, E.Joly, G.W.Butcher, I.A.Wilson 81 11163232 Immunity Bulged Structures for an Unusually Long Peptide Bound to Rat Mhc Class Irt1-A(A) 14 2001
1BII A.Achour, K.Persson, R.A.Harris, J.Sundback, C.L.Sentman, Y.Lindqvist, G.Schneider, K.Karre 199 9729040 Immunity The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition. 9 1998
1K8D X.He, P.Tabaczewski, J.Ho, I.Stroynowski, K.C.Garcia 1213 11738047 Structure Promiscuous Antigen Presentation by the Nonclassical Mhc Ib Qa-2 is Enabled by a Shallow, Hydrophobic Groove and Self-Stabilized Peptide Conformation 9 2001
1S7U L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7V L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7W L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7X L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1QO3 J.Tormo, K.Natarajan, D.H.Margulies, R.A.Mariuzza 623 10604468 Nature Crystal Structure of a Lectin-Like Natural Killer Cell Receptor Bound to its Mhc Class I Ligand 402 1999
1WBX R.Meijers, C.Lai, Y.Yang, J.Liu, W.Zhong, J.Wang, E.L.Reinherz 1099 n/a J.Mol.Biol. Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance 345 2005
1N5A A.Achour, J.Michaelsson, R.A.Harris, J.Odeberg, P.Grufman, J.K.Sandberg, V.Levitsky, K.Karre, T.Sandalova, G.Schneider 757 12479822 Immunity A Structural Basis for Lcmv Immune Evasion. Subversion of H-2D(B) and H-2K(B) Presentation of Gp33 Revealed by Comparative Crystal Structure Analyses. 17 2002
1WBY R.Meijers, C.Lai, Y.Yang, J.Liu, W.Zhong, J.Wang, E.L.Reinherz 1099 n/a J.Mol.Biol. Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance 345 2005
1QLF A.Glithero, J.Tormo, J.S.Haurum, G.Arsequell, G.Valencia, J.Edwards, S.Springer, A.Townsend, Y.-L.Pao, M.Wormald, R.A.Dwek, E.Y.Jones, T.Elliot 63 10023771 Immunity Crystal Structures of Two H-2Db/Glycopeptide Complexes Suggest a Molecular Basis for Ctl Cross-Reactivity 10 1999
1T0N A.I.Webb, N.A.Borg, M.A.Dunstone, L.Kjer-Nielsen, T.Beddoe, J.Mccluskey, F.R.Carbone, S.P.Bottomley, M.I.Aguilar, A.W.Purcell, J.Rossjohn 402 15210799 J.Immunol. The Structure of H-2K(B) and K(Bm8) Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch that Governs T Cell Repertoire Selection and Viral Resistance 173 2004
1RJZ M.J.Miley, I.Messaoudi, B.M.Metzner, Y.Wu, J.Nikolich-Zugich, D.H.Fremont 1445 15557346 J.Exp.Med. Structural Basis for the Restoration of Tcr Recognition of an Mhc Allelic Variant by Peptide Secondary Anchor Substitution 200 2004
1N3N C.Ciatto, G.Capitani, A.C.Tissot, F.Pecorari, A.Plueckthun, M.G.Gruetter 11 12753896 FEBS Lett. Structural Analysis of Mycobacterial and Murine Hsp60 Epitopes in Complex with the Class I Mhc Molecule H-2D(B) 543 2003
1RJY M.J.Miley, I.Messaoudi, B.M.Metzner, Y.Wu, J.Nikolich-Zugich, D.H.Fremont 1445 15557346 J.Exp.Med. Structural Basis for the Restoration of Tcr Recognition of an Mhc Allelic Variant by Peptide Secondary Anchor Substitution 200 2004
1FG2 A.C.Tissot, C.Ciatto, P.R.E.Mittl, M.G.Gruetter, A.Plueckthun 873 10993729 J.Mol.Biol. Viral Escape at the Molecular Level Explained by Quantitative T-Cell Receptor/Peptide/Mhc Interactions and the Crystal Structure of a Peptide/Mhc Complex 302 2000
1JPG C.Ciatto, A.C.Tissot, M.Tschopp, G.Capitani, F.Pecorari, A.Pluckthun, M.G.Grutter 1059 11580250 J.Mol.Biol. Zooming in on the Hydrophobic Ridge of H-2D(B): Implications for the Conformational Variability of Bound Peptides 312 2001
1JPF C.Ciatto, A.C.Tissot, M.Tschopp, G.Capitani, F.Pecorari, A.Pluckthun, M.G.Grutter 1059 11580250 J.Mol.Biol. Zooming in on the Hydrophobic Ridge of H-2D(B): Implications for the Conformational Variability of Bound Peptides 312 2001
1LDP J.A.Speir, K.C.Garcia, A.Brunmark, M.Degano, P.A.Peterson, L.Teyton, I.A.Wilson 553 9620676 Immunity Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes. 8 1998
1N59 A.Achour, J.Michaelsson, R.A.Harris, J.Odeberg, P.Grufman, J.K.Sandberg, V.Levitsky, K.Karre, T.Sandalova, G.Schneider 757 12479822 Immunity A Structural Basis for Lcmv Immune Evasion. Subversion of H-2D(B) and H-2K(B) Presentation of Gp33 Revealed by Comparative Crystal Structure Analyses. 17 2002
1KJ2 J.-B.Reiser, C.Gregoire, C.Darnault, T.Mosser, A.Guimezanes, A.-M.Schmitt-Verhulst, J.C.Fontecilla-Camps, G.Mazza, B.Malissen, D.Housset 345 11911820 Immunity A T-Cell Receptor Cdr3Beta Loop Undergoes Conformational Changes of Unprecedented Magnitude Upon Binding to a Peptide/Mhc Class I Complex 16 2002
1NAN J.-B.Reiser, C.Darnault, C.Gregoire, T.Mosser, G.Mazza, A.Kearnay, P.A.Van Der Merwe, J.C.Fontecilla-Camps, D.Housset, B.Malissen 241 12563259 Nat.Immunol. Cdr3 Loop Flexibility Contributes to the Degeneracy of Tcr Recognition 4 2003
1T0M A.I.Webb, N.A.Borg, M.A.Dunstone, L.Kjer-Nielsen, T.Beddoe, J.Mccluskey, F.R.Carbone, S.P.Bottomley, M.I.Aguilar, A.W.Purcell, J.Rossjohn 402 15210799 J.Immunol. The Structure of H-2K(B) and K(Bm8) Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch that Governs T Cell Repertoire Selection and Viral Resistance 173 2004
1KJ3 J.-B.Reiser, C.Gregoire, C.Darnault, T.Mosser, A.Guimezanes, A.-M.Schmitt-Verhulst, J.C.Fontecilla-Camps, G.Mazza, B.Malissen, D.Housset 345 11911820 Immunity A T-Cell Receptor Cdr3Beta Loop Undergoes Conformational Changes of Unprecedented Magnitude Upon Binding to a Peptide/Mhc Class I Complex 16 2002
1S7Q L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7R L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7T L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1S7S L.M.Velloso, J.Michaelsson, H.G.Ljunggren, G.Schneider, A.Achour 5504 15100292 J.Immunol. Determination of Structural Principles Underlying Three Different Modes of Lymphocytic Choriomeningitis Virus Escape from Ctl Recognition. 172 2004
1INQ D.A.Ostrov, M.M.Roden, W.Shi, E.Palmieri, G.J.Christianson, L.Mendoza, G.Villaflor, D.Tilley, N.Shastri, H.Grey, S.C.Almo, D.Roopenian, S.G.Nathenson 283 11751972 J.Immunol. How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional Mhc Binding Anchor Motifs Determine Self-Nonself Discrimination 168 2002
1JUF D.A.Ostrov, M.M.Roden, W.Shi, E.Palmieri, G.J.Christianson, L.Mendoza, G.Villaflor, D.Tilley, N.Shastri, H.Grey, S.C.Almo, D.C.Roopenian, S.G.Nathenson 283 11751972 J.Immunol. How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional Mhc Binding Anchor Motifs Determine Self-Nonself Discrimination. 168 2002
1DDH H.Li, K.Natarajan, E.L.Malchiodi, D.H.Margulies, R.A.Mariuzza 179 9761682 J Mol Biol Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120. 283 1998
1FZO M.G.Rudolph, J.A.Speir, A.Brunmark, N.Mattsson, M.R.Jackson, P.A.Peterson, L.Teyton, I.A.Wilson 231 11290333 Immunity The Crystal Structures of Kbm1 and Kbm8 Reveal that Subtle Changes in the Peptide Environment Impact Thermostability and Alloreactivity 14 2001
1FZM M.G.Rudolph, J.A.Speir, A.Brunmark, N.Mattsson, M.R.Jackson, P.A.Peterson, L.Teyton, I.A.Wilson 231 11290333 Immunity The Crystal Structures of Kbm1 and Kbm8 Reveal that Subtle Changes in the Peptide Environment Impact Thermostability and Alloreactivity 14 2001
1WBZ R.Meijers, C.Lai, Y.Yang, J.Liu, W.Zhong, J.Wang, E.L.Reinherz 1099 n/a J.Mol.Biol. Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance 345 2005
1NAM J.-B.Reiser, C.Darnault, C.Gregoire, T.Mosser, G.Mazza, A.Kearnay, P.A.Van Der Merwe, J.C.Fontecilla-Camps, D.Housset, B.Malissen 241 12563259 Nat.Immunol. Cdr3 Loop Flexibility Contributes to the Degeneracy of Tcr Recognition 4 2003
1FO0 J.B.Reiser, C.Darnault, A.Guimezanes, C.Gregoire, T.Mosser, A-M.Schmitt-Verhulst, J.C.Fontecilla-Camps, B.Malissen, D.Housset, G.Mazza 291 11017099 Nat.Immunol. Crystal Structure of a T Cell Receptor Bound to an Allogeneic Mhc Molecule 1 2000
1CE6 A.Glithero, J.Tormo, J.S.Haurum, G.Arsequell, G.Valencia, J.Edwards, S.Springer, A.Townsend, Y.L.Pao, M.Wormald, R.A.Dwek, E.Y.Jones, T.Elliott 63 10023771 Immunity Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity. 10 1999
1BZ9 R.Zhao, D.J.Loftus, E.Appella, E.J.Collins 359 9892618 J Exp Med Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry. 189 1999
1LEG J.G.Luz, M.Huang, K.C.Garcia, M.G.Rudolph, V.Apostolopoulos, L.Teyton, I.A.Wilson 1175 11994422 J.Exp.Med. Structural Comparison of Allogeneic and Syngeneic T Cell Receptor-Peptide-Major Histocompatibility Complex Complexes: A Buried Alloreactive Mutation Subtly Alters Peptide Presentation Substantially Increasing V Beta Interactions. 95 2002
1KBG J.A.Speir, U.M.Abdel-Motal, M.Jondal, I.A.Wilson 51 10023770 Immunity Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL. 10 1999
1VAD D.H.Fremont, E.A.Stura, M.Matsumura, P.A.Peterson, I.A.Wilson 2479 7708669 Proc Natl Acad Sci U S A Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. 92 1995
1VAC D.H.Fremont, E.A.Stura, M.Matsumura, P.A.Peterson, I.A.Wilson 2479 7708669 Proc Natl Acad Sci U S A Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. 92 1995
1KPV M.G.Rudolph, I.A.Wilson n/a n/a To be Published High Resolution Crystal Structure of H-2Kb/Vsv8 n/a n/a
1BQH P.S.Kern, M.K.Teng, A.Smolyar, J.H.Liu, J.Liu, R.E.Hussey, R.Spoerl, H.C.Chang, E.L.Reinherz, J.H.Wang 519 9806638 Immunity Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb. 9 1998
1P4L J.Dam, R.Guan, K.Natarajan, N.Dimasi, L.K.Chlewicki, D.M.Kranz, P.Schuck, D.H.Margulies, R.A.Mariuzza 1213 14595439 Nat.Immunol. Variable Mhc Class I Engagement by Ly49 Natural Killer Cell Receptors Demonstrated by the Crystal Structure of Ly49C Bound to H-2K(B). 4 2003
2CKB K.C.Garcia, M.Degano, L.R.Pease, M.Huang, P.A.Peterson, L.Teyton, I.A.Wilson 1166 9469799 Science Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. 279 1998
1G7P V.Apostolopoulos, M.Yu, A.L.Corper, W.Li, I.F.Mckenzie, L.Teyton, I.A.Wilson 1307 12083519 J.Mol.Biol. Crystal Structure of a Non-Canonical High Affinity Peptide Complexed with Mhc Class I: A Novel Use of Alternative Anchors 318 2002
1G7Q V.Apostolopoulos, M.Yu, A.L.Corper, L.Teyton, G.A.Pietersz, I.F.Mckenzie, I.A.Wilson 1293 12083518 J.Mol.Biol. Crystal Structure of a Non-Canonical Low-Affinity Peptide Complexed with Mhc Class I: A New Approach for Vaccine Design 318 2002
1P1Z J.Dam, R.Guan, K.Natarajan, N.Dimasi, L.K.Chlewicki, D.M.Kranz, P.Schuck, D.H.Margulies, R.A.Mariuzza 1213 14595439 Nat.Immunol. Variable Mhc Class I Engagement by Ly49 Natural Killer Cell Receptors Demonstrated by the Crystal Structure of Ly49C Bound to H-2K(B). 4 2003
1G6R M.Degano, K.C.Garcia, V.Apostolopoulos, M.G.Rudolph, L.Teyton, I.A.Wilson 251 10755612 Immunity A Functional Hot Spot for Antigen Recognition in a Superagonist Tcr/Mhc Complex 12 2000
1RK0 M.J.Miley, I.Messaoudi, B.M.Metzner, Y.Wu, J.Nikolich-Zugich, D.H.Fremont 1445 15557346 J.Exp.Med. Structural Basis for the Restoration of Tcr Recognition of an Mhc Allelic Variant by Peptide Secondary Anchor Substitution 200 2004
1RK1 M.J.Miley, I.Messaoudi, B.M.Metzner, Y.Wu, J.Nikolich-Zugich, D.H.Fremont 1445 15557346 J.Exp.Med. Structural Basis for the Restoration of Tcr Recognition of an Mhc Allelic Variant by Peptide Secondary Anchor Substitution 200 2004
1KPU M.G.Rudolph, I.A.Wilson n/a n/a To be Published High Resolution Crystal Structure of H-2Kb/Vsv8 n/a n/a
1OSZ Y.Ghendler, M.K.Teng, J.H.Liu, T.Witte, J.Liu, K.S.Kim, P.Kern, H.C.Chang, J.H.Wang, E.L.Reinherz 10061 9707600 Proc Natl Acad Sci U S A Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands. 95 1998
2VAA D.H.Fremont, M.Matsumura, E.A.Stura, P.A.Peterson, I.A.Wilson 919 1323877 Science Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. 257 1992
1LK2 J.G.Luz, M.G.Rudolph, I.A.Wilson, H.Eisen n/a n/a To be Published Crystal Structure of the Class I Mhc H-2Kb/Gnys Complex n/a n/a
2VAB D.H.Fremont, M.Matsumura, E.A.Stura, P.A.Peterson, I.A.Wilson 919 1323877 Science Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. 257 1992
1FFP B.Wang, A.Sharma, R.Maile, M.Saad, E.J.Collins, J.A.Frelinger 3137 12218131 J.Immunol. Peptidic Termini Play a Significant Role in Tcr Recognition 169 2002
1FFO Sharma A.K., M.Saad, B Wang, J.A.Frelinger, E.J.Collins 3137 n/a J.Immunol. Peptidic Termini Play a Significant Role in Tcr Recognition 169 2002
1FFN B.Wang, A.Sharma, R.Maile, M.Saad, E.J.Collins, J.A.Frelinger 3137 12218131 J.Immunol. Peptidic Termini Play a Significant Role in Tcr Recognition 169 2002
1FZK M.G.Rudolph, J.A.Speir, A.Brunmark, N.Mattsson, M.R.Jackson, P.A.Peterson, L.Teyton, I.A.Wilson 231 11290333 Immunity The Crystal Structures of Kbm1 and Kbm8 Reveal that Subtle Changes in the Peptide Environment Impact Thermostability and Alloreactivity 14 2001
1FZJ M.G.Rudolph, J.A.Speir, A.Brunmark, N.Mattsson, M.R.Jackson, P.A.Peterson, L.Teyton, I.A.Wilson 231 11290333 Immunity The Crystal Structures of Kbm1 and Kbm8 Reveal that Subtle Changes in the Peptide Environment Impact Thermostability and Alloreactivity 14 2001
1LD9 G.K.Balendiran, J.C.Solheim, A.C.Young, T.H.Hansen, S.G.Nathenson, J.C.Sacchettini 6880 9192660 Proc Natl Acad Sci U S A The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide. 94 1997
1LEK J.G.Luz, M.Huang, K.C.Garcia, M.G.Rudolph, V.Apostolopoulos, L.Teyton, I.A.Wilson 1175 11994422 J.Exp.Med. Structural Comparison of Allogeneic and Syngeneic T Cell Receptor-Peptide-Major Histocompatibility Complex Complexes: A Buried Alloreactive Mutation Subtly Alters Peptide Presentation Substantially Increasing V(Beta) Interactions 195 2002
1MWA J.G.Luz, M.D.Huang, K.C.Garcia, M.G.Rudolph, L.Teyton, I.A.Wilson 1175 11994422 J.Exp.Med. Structural Comparison of Allogeneic and Syngeneic T Cell Receptor Peptide-Major Histocompatibility Complex Complexes: A Buried Alloreactive Mutation Subtly Alters Peptide Presentation Substantially Increasing Vbeta Interactions 195 2002
1HOC A.C.Young, W.Zhang, J.C.Sacchettini, S.G.Nathenson 39 7506996 Cell The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection. 76 1994
1KJV M.G.Rudolph, J.Stevens, J.A.Speir, J.Trowsdale, G.W.Butcher, E.Joly, I.A.Wilson 975 12470953 J.Mol.Biol. Crystal Structures of Two Rat Mhc Class Ia (RT1-A) Molecules that are Associated Differentially with Peptide Transporter Alleles Tap-A and Tap-B. 324 2002
2MHA W.Zhang, A.C.Young, M.Imarai, S.G.Nathenson, J.C.Sacchettini 8403 1325657 Proc Natl Acad Sci U S A Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. 89 1992
1MHC C.R.Wang, A.R.Castano, P.A.Peterson, C.Slaughter, K.F.Lindahl, J.Deisenhofer 655 7664344 Cell Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3. 82 1995
1NEZ Y.Liu, Y.Xiong, O.V.Naidenko, J.H.Liu, R.Zhang, A.Joachimiak, M.Kronenberg, H.Cheroutre, E.L.Reinherz, J.H.Wang 205 12594948 Immunity The Crystal Structure of a Tl/Cd8Alphaalpha Complex at 2.1 A Resolution: Implications for Modulation of T Cell Activation and Memory 18 2003
1TMC E.J.Collins, D.N.Garboczi, M.N.Karpusas, D.C.Wiley 1218 7862664 Proc Natl Acad Sci U S A The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain. 92 1995
1C16 C.Wingren, M.P.Crowley, M.Degano, Y.Chien, I.A.Wilson 310 10634787 Science Crystal Structure of a Gammadelta T Cell Receptor Ligand T22: A Truncated Mhc-Like Fold. 287 2000
1ONQ D.M.Zajonc, M.A.Elsliger, L.Teyton, I.A.Wilson 808 12833155 Nat.Immunol. Crystal Structure of Cd1A in Complex with a Sulfatide Self Antigen at a Resolution of 2.15 A. 4 2003
1R3H M.G.Rudolph, C.Wingren, M.P.Crowley, Y.-H.Chien, I.A.Wilson 656 n/a Acta Crystallogr., Sect.D Combined Pseudo-Merohedral Twinning, Non-Crystallographic Symmetry and Pseudo-Translation in a Monoclinic Crystal Form of the Gd T Cell Ligand T10 60 2004
1DE4 M.J.Bennett, J.A.Lebron, P.J.Bjorkman 46 10638746 Nature Crystal Structure of the Hereditary Haemochromatosis Protein Hfe Complexed with Transferrin Receptor 403 2000
1EXU A.P.West Jr., P.J.Bjorkman 9698 10933786 Biochemistry Crystal Structure and Immunoglobulin G Binding Properties of the Human Major Histocompatiblity Complex-Related Fc Receptor 39 2000
1A6Z J.A.Lebron, M.J.Bennett, D.E.Vaughn, A.J.Chirino, P.M.Snow, G.A.Mintier, J.N.Feder, P.J.Bjorkman 111 9546397 Cell Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. 93 1998
1GZP S.D.Gadola, N.R.Zaccai, K.Harlos, D.Shepherd, J.C.Castro-Palomino, G.Ritter, R.R.Schmidt, E.Y.Jones, V.Cerundolo 721 12118248 Nat.Immunol. Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains 3 2002
1UQS T.Batuwangala, D.Shepherd, S.D.Gadola, K.J.C.Gibson, N.R.Zaccai, A.R.Fersht, G.S.Besra, V.Cerundolo, E.Y.Jones 2382 n/a J.Immunol. The Crystal Structure of Human Cd1B with a Bound Bacterial Glycolipid 172 2004
1LDS C.H.Trinh, D.P.Smith, A.P.Kalverda, S.E.V.Phillips, S.E.Radford 9771 12119416 Proc.Nat.Acad.Sci.USA Crystal Structure of Monomeric Human Beta-2-Microglobulin Reveals Clues to its Amyloidogenic Properties 99 2002
1GZQ S.D.Gadola, N.R.Zaccai, K.Harlos, D.Shepherd, J.C.Castro-Palomino, G.Ritter, R.R.Schmidt, E.Y.Jones, V.Cerundolo 721 12118248 Nat.Immunol. Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains 3 2002
1JNJ G.Verdone, A.Corazza, P.Viglino, F.Pettirossi, S.Giorgetti, P.Mangione, A.Andreola, M.Stoppini, V.Bellotti, G.Esposito 487 11847272 Protein Sci. The Solution Structure of Human Beta2-Microglobulin Reveals the Prodromes of its Amyloid Transition 11 2002
1PY4 C.Rosano, S.Zuccotti, P.Mangione, S.Giorgetti, V.Bellotti, F.Pettirossi, A.Corazza, P.Viglino, G.Esposito, M.Bolognesi 1051 14698299 J.Mol.Biol. Beta2-Microglobulin H31Y Variant 3D Structure Highlights the Protein Natural Propensity Towards Intermolecular Aggregation 335 2004
1ZAG L.M.Sanchez, A.J.Chirino, P.j.Bjorkman 1914 10206894 Science Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules. 283 1999
1T7Z S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1T80 S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1T7V S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1T7W S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1T7X S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1T7Y S.L.Delker, A.P.West Jr., L.Mcdermott, M.W.Kennedy, P.J.Bjorkman 205 15477100 J.Struct.Biol. Crystallographic Studies of Ligand Binding by Zn-Alpha2-Glycoprotein. 148 2004
1BMG J.W.Becker, G.N.Reeke Jr. 4225 3889925 Proc Natl Acad Sci U S A Three-dimensional structure of beta 2-microglobulin. 82 1985
3FRU D.E.Vaughn, P.J.Bjorkman 63 9493268 Structure Structural basis of pH-dependent antibody binding by the neonatal Fc receptor. 6 1998
1FRT W.P.Burmeister, A.H.Huber, P.J.Bjorkman 379 7969498 Nature Crystal structure of the complex of rat neonatal Fc receptor with Fc. 372 1994
1I1A W.L.Martin, A.P.West Jr., L.Gan, P.J.Bjorkman 867 11336709 Mol. Cell Crystal Structure at 2.8A of an Fcrn/Heterodimeric Fc Complex: Mechanism of Ph-Dependent Binding. 7 2001
1CD1 Z.Zeng, A.R.Castano, B.W.Segelke, E.A.Stura, P.A.Peterson, I.A.Wilson 339 9219685 Science Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. 277 1997
1PQZ M.J.Miley, D.H.Fremont n/a n/a To be Published Murine Cytomegalovirus Immunomodulatory Protein M144 n/a n/a
1B3J P.Li, S.Willie, S.Bauer, D.Morris, T.Spies, R.Strong 577 10367903 Immunity Crystal Structure of the Mhc Class I Homolog Mic-A, a Gammadelta T Cell Ligand 10 1999
1HYR P.Li, D.L.Morris, B.E.Willcox, A.Steinle, T.Spies, R.K.Strong 443 11323699 Nat.Immunol. Complex Structure of the Activating Immunoreceptor Nkg2D and its Mhc Class I-Like Ligand Mica 2 2001
1JE6 M.A.Holmes, P.Li, E.W.Petersdorf, R.K.Strong 1395 12133964 J.Immunol. Structural Studies of Allelic Diversity of the Mhc Class I Homolog Mic-B, a Stress-Inducible Ligand for the Activating Immunoreceptor Nkg2D 169 2002
1MUJ Y.Zhu, A.Y.Rudensky, A.L.Teyton, I.A.Wilson 1157 12589760 J.Mol.Biol. Crystal Structure of Mhc Class II I-Ab in Complex with a Human Clip Peptide: Prediction of an I-Ab Peptide-Binding Motif 326 2003
1ES0 A.L.Corper, T.Stratmann, V.Apostolopoulos, C.A.Scott, K.C.Garcia, A.S.Kang, I.A.Wilson, L.Teyton 501 10775108 Science A Structural Framework for Deciphering the Link between I-A(G7) and Autoimmune Diabetes 288 2000
1IAO C.A.Scott, P.A.Peterson, L.Teyton, I.A.Wilson 319 9529149 Immunity Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. 8 1998
1LNU X.Liu, S.Dai, F.Crawford, R.Fruge, P.Marrack, J.Kappler 8820 12084926 Proc.Nat.Acad.Sci.USA Alternate Interactions Define the Binding of Peptides to the Mhc Molecule Iab 99 2002
2IAD C.A.Scott, P.A.Peterson, L.Teyton, I.A.Wilson 319 9529149 Immunity Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. 8 1998
1JL4 J.-H.Wang, R.Meijers, Y.Xiong, J.-H.Liu, T.Sakihama, R.Zhang, A.Joachimiak, E.L.Reinherz 10799 11535811 Proc.Nat.Acad.Sci.USA Crystal Structure of the Human Cd4 N-Terminal Two-Domain Fragment Complexed to a Class II Mhc Molecule 98 2001
1IAK D.H.Fremont, D.Monnaie, C.A.Nelson, W.A.Hendrickson, E.R.Unanue 305 9529148 Immunity Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. 8 1998
1D9K E.L.Reinherz, K.Tan, L.Tang, P.Kern, J.Liu, Y.Xiong, R.E.Hussey, A.Smolyar, B.Hare, R.Zhang, A.Joachimiak, H.C.Chang, G.Wagner, J.Wang 1913 10583947 Science The Crystal Structure of a T Cell Receptor in Complex with Peptide and Mhc Class II 286 1999
1F3J R.R.Latek, A.Suri, S.J.Petzold, C.A.Nelson, O.Kanagawa, E.R.Unanue, D.H.Fremont 699 10894169 Immunity Structural Basis of Peptide Binding and Presentation by the Type 1 Diabetes-Associated Mhc Class II Molecule of Nod Mice 12 2000
1HDM L.Mosyak, D.M.Zaller, D.C.Wiley 377 9768757 Immunity The Structure of Hla-Dm, the Peptide Exchange Catalyst that Loads Antigen Onto Class II Mhc Molecules During Antigen Presentation 9 1998
1FV1 Y.Li, H.Li, R.Martin, A.R.Mariuzza 177 11080454 J.Mol.Biol. Structural Basis for the Binding of an Immunodominant Peptide from Myelin Basic Protein in Different Registers by Two Hla-Dr2 Alleles 304 2000
1HQR Y.Li, H.Li, N.Dimasi, J.K.Mccormick, R.Martin, P.Schuck, P.Schlievert, R.Mariuzza 93 11163233 Immunity Crystal Structure of a Superantigen Bound to the High-Affinity, Zinc-Dependent Site on Mhc Class II 14 2001
1H15 H.Lang, H.Jacobsen, S.Ikemizu, C.Andersson, K.Harlos, L.Madsen, P.Hjorth, L.Sondergaard, A.Svejgaard, K.Wucherpfennig, D.Stuart, J.Bell, E.Y.Jones, L.Fugger 940 12244309 Nat.Immunol. A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis 3 2002
2SEB A.Dessen, C.M.Lawrence, S.Cupo, D.M.Zaller, D.C.Wiley 473 9354468 Immunity X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II. 7 1997
1D5X D.R.Bolin, A.L.Swain, R.Sarabu, S.J.Berthel, P.Gillespie, N.J.Huby, R.Makofske, L.Orzechowski, A.Perrotta, K.Toth, J.P.Cooper, N.Jiang, F.Falcioni, R.Campbell, D.Cox, D.Gaizband, C.J.Belunis, D.Vidovic, K.Ito, R.Crowther, U.Kammlott, X.Zhang, R.Palermo, D.Weber, J.Guenot 2135 10841792 J.Med.Chem. Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by Hla-Dr Class II Mhc Molecules. Design, Structure-Activity Relationships, and X-Ray Crystal Structures 43 2000
1D6E D.R.Bolin, A.L.Swain, R.Sarabu, S.J.Berthel, P.Gillespie, N.J.Huby, R.Makofske, L.Orzechowski, A.Perrotta, K.Toth, J.P.Cooper, N.Jiang, F.Falcioni, R.Campbell, D.Cox, D.Gaizband, C.J.Belunis, D.Vidovic, K.Ito, R.Crowther, U.Kammlott, X.Zhang, R.Palermo, D.Weber, J.Guenot 2135 10841792 J.Med.Chem. Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by Hla-Dr Class II Mhc Molecules. Design, Structure-Activity Relationships, and X-Ray Crystal Structures 43 2000
1D5Z D.R.Bolin, A.L.Swain, R.Sarabu, S.J.Berthel, P.B.Gillespie, N.J.S.Huby, R.Makofski, L.Orzechowski, A.Perrotta, K.Toth, J.P.Cooper, N.Jiang, F.Falcioni, R.Campbell, D.Cox, D.Gaizband, C.J.Belunis, D.Vidovic, K.Ito, R.Crowther, U.Kammlott, X.Zhang, R.Palermo, D.Weber, J.Gu 2135 10841792 J.Med.Chem. Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by Hla-Dr Class II Mhc Molecules. Design, Structure-Activity Relationships, and X-Ray Crystal Structures 43 2000
1K2D X.L.He, C.Radu, J.Sidney, A.Sette, E.S.Ward, K.C.Garcia 83 12150894 Immunity Structural Snapshot of Aberrant Antigen Presentation Linked to Autoimmunity: The Immunodominant Epitope of Mbp Complexed with I-Au 17 2002
1KG0 M.M.Mullen, K.M.Haan, R.Longnecker, T.S.Jardetzky 375 11864610 Mol. Cell Structure of the Epstein-Barr Virus Gp42 Protein Bound to the Mhc Class II Receptor Hla-Dr1 9 2002
1DLH L.J.Stern, J.H.Brown, T.S.Jardetzky, J.C.Gorga, R.G.Urban, J.L.Strominger, D.C.Wiley 215 8145819 Nature Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. 368 1994
1JWM E.J.Sundberg, P.S.Andersen, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 1151 12962633 Structure Structural, Energetic, and Functional Analysis of a Protein-Protein Interface at Distinct Stages of Affinity Maturation 11 2003
1R5I Y.Zhao, Z.Li, S.J.Drozd, Y.Guo, W.Mourad, H.Li 277 14962388 Structure Crystal Structure of Mycoplasma Arthritidis Mitogen Complexed with Hla-Dr1 Reveals a Novel Superantigen Fold and a Dimerized Superantigen-Mhc Complex. 12 2004
1LO5 K.Petersson, M.Thunnissen, G.Forsberg, B.Walse 1619 12467569 Structure Crystal Structure of a Sea Variant in Complex with Mhc Class II Reveals the Ability of Sea to Crosslink Mhc Molecules 10 2002
1PYW Z.Zavala-Ruiz, E.J.Sundberg, J.D.Stone, D.B.Deoliveira, I.C.Chan, J.Svendsen, R.A.Mariuzza, L.J.Stern 44904 12952957 J.Biol.Chem. Exploration of the P6/P7 Region of the Peptide-Binding Site of the Human Class II Major Histocompatability Complex Protein Hla-Dr1 278 2003
1SJE Z.Zavala-Ruiz, I.Strug, B.D.Walker, P.J.Norris, L.J.Stern 13279 15331779 Proc.Natl.Acad.Sci.USA A Hairpin Turn in a Class II Mhc-Bound Peptide Orients Residues Outside the Binding Groove for T Cell Recognition. 101 2004
1T5X Z.Zavala-Ruiz, I.Strug, M.W.Anderson, J.Gorski, L.J.Stern n/a n/a To be Published Side Chain Specificity at the P10 Position of the Peptide Binding Site of a Class II Major Histocompatibility Protein n/a n/a
1HXY K.Petersson, M.Hakansson, H.Nilsson, G.Forsberg, L.A.Svensson, A.Liljas, B.Walse 1 11432818 Embo J. Crystal Structure of a Superantigen Bound to Mhc Class II Displays Zinc and Peptide Dependence 20 2001
1T5W Z.Zavala-Ruiz, I.Strug, M.W.Anderson, J.Gorski, L.J.Stern n/a n/a To be Published Side Chain Specificity at the P10 Position of the Peptide Binding Site of a Class II Major Histocompatibility Protein n/a n/a
1JWU E.J.Sundberg, P.S.Andersen, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 1151 12962633 Structure Structural, Energetic, and Functional Analysis of a Protein-Protein Interface at Distinct Stages of Affinity Maturation 11 2003
1KLG E.J.Sundberg, M.W.Sawicki, S.Southwood, P.S.Andersen, A.Sette, R.A.Mariuzza 449 12051920 J.Mol.Biol. Minor Structural Changes in a Mutated Human Melanoma Antigen Correspond to Dramatically Enhanced Stimulation of a Cd4+ Tumor-Infiltrating Lymphocyte Line 319 2002
1SJH Z.Zavala-Ruiz, I.Strug, B.D.Walker, P.J.Norris, L.J.Stern 13279 15331779 Proc.Natl.Acad.Sci.USA A Hairpin Turn in a Class II Mhc-Bound Peptide Orients Residues Outside the Binding Groove for T Cell Recognition. 101 2004
1KLU E.J.Sundberg, M.W.Sawicki, S.Southwood, P.S.Andersen, A.Sette, R.A.Mariuzza 449 12051920 J.Mol.Biol. Minor Structural Changes in a Mutated Human Melanoma Antigen Correspond to Dramatically Enhanced Stimulation of a Cd4+ Tumor-Infiltrating Lymphocyte Line 319 2002
1JWS E.J.Sundberg, P.S.Andersen, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 1151 12962633 Structure Structural, Energetic, and Functional Analysis of a Protein-Protein Interface at Distinct Stages of Affinity Maturation 11 2003
1D5M D.R.Bolin, A.L.Swain, R.Sarabu, S.J.Berthel, P.B.Gillespie, N.J.S.Huby, R.Makofski, L.Orzechowski, A.Perrotta, K.Toth, J.P.Cooper, N.Jiang, F.Falcioni, R.Campbell, D.Cox, D.Gaizband, D.Vidovic, K.Ito, R.Crowther, U.Kammlott, R.Palermo, D.Weber, J.Guenot, Z.Nagy, G.L.Olson 2135 10841792 J.Med.Chem. Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by Hla-Dr Class II Mhc Molecules. Design, Structure-Activity Relationships, and X-Ray Crystal Structures 43 2000
1J8H J.Hennecke, D.C.Wiley 571 11877480 J.Exp.Med. Structure of a Complex of the Human Alpha/Beta T Cell Receptor (Tcr) Ha1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, Hla-Dr4 (Dra0101 and Drb10401): Insight Into Tcr Cross-Restriction and Alloreactivity 195 2002
1FYT J.Hennecke, A.Carfi, D.C.Wiley 5611 11060013 Embo J. Structure of a Covalently Stabilized Complex of a Human Ab-T Cell Receptor, Influenza Ha Peptide and Mhc Class II Molecule, Hla-Dr1 19 2000
1SEB T.S.Jardetzky, J.H.Brown, J.C.Gorga, L.J.Stern, R.G.Urban, Y.I.Chi, C.Stauffacher, J.L.Strominger, D.C.Wiley 711 8152483 Nature Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. 368 1994
1AQD V.L.Murthy, L.J.Stern 1385 9351812 Structure The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding. 5 1997
1S9V C.-Y.Kim, H.Quarsten, E.Bergseng, C.Khosla, L.M.Sollid 4175 15020763 Proc.Nat.Acad.Sci.USA Structural Basis for Hla-Dq2-Mediated Presentation of Gluten Epitopes in Celiac Disease 101 2004
1UVQ C.Siebold, B.E.Hansen, J.R.Wyer, K.Harlos, R.E.Esnouf, A.Svejgaard, J.I.Bell, J.L.Strominger, E.Y.Jones, L.Fugger 1999 n/a Proc.Nat.Acad.Sci.USA Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy 101 2004
1BX2 K.J.Smith, J.Pyrdol, L.Gauthier, D.C.Wiley, K.W.Wucherpfennig 1511 9782128 J Exp Med Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein. 188 1998
1JK8 K.H.Lee, K.W.Wucherpfennig, D.C.Wiley 501 11376336 Nat.Immunol. Structure of a Human Insulin Peptide-Hla-Dq8 Complex and Susceptibility to Type 1 Diabetes 2 2001
1A6A P.Ghosh, M.Amaya, E.Mellins, D.C.Wiley 457 7477400 Nature The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. 378 1995
1K8I D.H.Fremont, F.Crawford, P.Marrack, W.Hendrickson, J.Kappler 385 9768758 Immunity Crystal Structure of Mouse H2-M 9 1998
1KCG S.Radaev, B.Rostro, A.G.Brooks, M.Colonna, P.Sun 1039 11754823 Immunity Conformational Plasticity Revealed by the Cocrystal Structure of Nkg2D and its Class I Mhc-Like Ligand Ulbp3 15 2001
1R5W M.Krogsgaard, N.Prado, E.J.Adams, X.L.He, D.C.Chow, D.B.Wilson, K.C.Garcia, M.M.Davis 1367 14690592 Mol.Cell Evidence that Structural Rearrangements and/or Flexibility During Tcr Binding Can Contribute to T Cell Activation 12 2003
1R5V M.Krogsgaard, N.Prado, E.J.Adams, X.L.He, D.C.Chow, D.B.Wilson, K.C.Garcia, M.M.Davis 1367 14690592 Mol.Cell Evidence that Structural Rearrangements and/or Flexibility During Tcr Binding Can Contribute to T Cell Activation. 12 2003
1FNE G.J.Kersh, M.J.Miley, C.A.Nelson, A.Grakoui, S.Horvath, D.L.Donermeyer, J.Kappler, P.M.Allen, D.H.Fremont 3345 11207290 J.Immunol. Structural and Functional Consequences of Altering a Peptide Mhc Anchor Residue 166 2001
1FNG M.J.Miley, G.J.Kersh, C.A.Nelson, A.Grakoui, S.Horvath, D.L.Donermeyer, J.Kappler, P.M.Allen, D.H.Fremont 3345 11207290 J.Immunol. Structural and Functional Consequences of Altering a Peptide Mhc Anchor Residue 166 2001
1IEB D.H.Fremont, W.A.Hendrickson, P.Marrack, J.Kappler 1001 8638119 Science Structures of an MHC class II molecule with covalently bound single peptides. 272 1996
1I3R N.Wilson, D.Fremont, P.Marrack, J.Kappler 513 11371354 Immunity Mutations Changing the Kinetics of Class II Mhc Peptide Exchange 14 2001
1IEA D.H.Fremont, W.A.Hendrickson, P.Marrack, J.Kappler 1001 8638119 Science Structures of an MHC class II molecule with covalently bound single peptides. 272 1996
1KT2 D.H.Fremont, S.Dai, H.Chiang, F.Crawford, P.Marrack, J.Kappler 1043 11956295 J.Exp.Med. Structural Basis of Cytochrome C Presentation by Ie(K) 195 2002
1KTD D.H.Fremont, S.Dai, H.Chiang, F.Crawford, P.Marrack, J.Kappler 1043 11956295 J.Exp.Med. Structural Basis of Cytochrome C Presentation by Ie(K) 195 2002
1FCC A.E.Sauer-Eriksson, G.J.Kleywegt, M.Uhlen, T.A.Jones 265 7788293 Structure Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. 3 1995
1H3Y S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1H3V S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1H3X S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1H3T S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1H3U S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1H3W S.Krapp, Y.Mimura, R.Jefferis, R.Huber, P.Sondermann 979 n/a J.Mol.Biol. Structural Analysis of Human Igg-Fc Glycoforms Reveals a Correlation between Glycosylation and Structural Integrity 325 2003
1FC2 J.Deisenhofer 2361 7236608 Biochemistry Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. 20 1981
1IIX S.Radaev, S.Motyka, W.-H.Fridman, C.Sautes-Fridman, P.D.Sun 16469 11297532 J.Biol.Chem. The Structure of a Human Type III Fc Gamma Receptor in Complex with Fc 276 2001
1FC1 J.Deisenhofer 2361 7236608 Biochemistry Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. 20 1981
1E4K P.Sondermann, R.Huber, V.Oosthuizen, U.Jacob 267 10917521 Nature The 3.2A Crystal Structure of the Human Igg1 Fc Fragment-Fc-Gamma-Riii Complex 406 2000
1T89 S.Radaev, S.Motyka, W.-H.Fridman, C.Sautes-Fridman, P.D.Sun 16469 11297532 J.Biol.Chem. The Structure of a Human Type III Fcgamma Receptor in Complex with Fc 276 2001
1T83 S.Radaev, S.Motyka, W.-H.Fridman, C.Sautes-Fridman, P.D.Sun 16469 11297532 J.Biol.Chem. The Structure of a Human Type III Fcgamma Receptor in Complex with Fc 276 2001
1DN2 W.L.DeLano, M.H.Ultsch, A.M.De Vos, J.A.Wells 1279 10678837 Science Convergent Solutions to Binding at a Protein-Protein Interface 287 2000
1L6X E.E.Idusogie, L.G.Presta, H.Santoro-Gazzano, K.Totpal, P.Y.Wong, M.Ultsch, Y.G.Meng, M.G.Mullkerrin 4178 10754313 J.Immunol. Mapping of the C1Q Binding Site on Rituxan, a Chimeric Antibody with a Human Igg1 Fc 164 2000
1OQO T.S.Raju, M.G.Mulkerrin, M.Parker, A.M.De Vos, H.Gazzano-Santoro, K.Totpal, M.H.Ultsch n/a n/a To be Published Impact of Fc Glycans on the Effector Functions Vary with the Antibody Mechanism of Action n/a n/a
1OQX T.S.Raju, M.G.Mulkerrin, M.Parker, A.M.De Vos, H.Gazzano-Santoro, K.Totpal, M.H.Ultsch n/a n/a To be Published Impact of Fc Glycans on the Effector Functions Vary with the Antibody Mechanism of Action n/a n/a
1ADQ A.L.Corper, M.K.Sohi, V.R.Bonagura, M.Steinitz, R.Jefferis, A.Feinstein, D.Beale, M.J.Taussig, B.J.Sutton 374 9145108 Nat Struct Biol Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction. 4 1997
1MCO L.W.Guddat, J.N.Herron, A.B.Edmundson 4271 8483943 Proc Natl Acad Sci U S A Three-dimensional structure of a human immunoglobulin with a hinge deletion. 90 1993
2IG2 H.D.Kratzin, W.Palm, M.Stangel, W.E.Schmidt, J.Friedrich, N.Hilschmann 263 2713105 Biol.Chem.Hoppe-Seyler Die Primaerstruktur Des Kristallisierbaren Monoklonalen Immunoglobulins Igg1 Kol. II. Aminosaeuresequenz Der L-Kette, Lambda-Typ, Subgruppe I (German) 370 1989
1IIS S.Radaev, S.Motyka, W.-H.Fridman, C.Sautes-Fridman, P.D.Sun 16469 11297532 J.Biol.Chem. The Structure of a Human Type III Fc Gamma Receptor in Complex with Fc 276 2001
1HZH E.O.Saphire, P.W.H.I.Parren, R.Pantophlet, M.B.Zwick, G.M.Morris, P.M.Rudd, R.A.Dwek, R.L.Stanfield, D.R.Burton, I.A.Wilson 1155 11498595 Science Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design 293 2001
1INE R.A.Love, J.E.Villafranca, R.M.Aust, K.K.Nakamura, R.A.Jue, J.G.Major Jr., R.Radhakrishnan, W.F.Butler 10950 8218161 Biochemistry How the anti-(metal chelate) antibody CHA255 is specific for the metal ion of its antigen: X-ray structures for two Fab'/hapten complexes with different metals in the chelate. 32 1993
1IND R.A.Love, J.E.Villafranca, R.M.Aust, K.K.Nakamura, R.A.Jue, J.G.Major Jr., R.Radhakrishnan, W.F.Butler 10950 8218161 Biochemistry How the anti-(metal chelate) antibody CHA255 is specific for the metal ion of its antigen: X-ray structures for two Fab'/hapten complexes with different metals in the chelate. 32 1993
1NJ9 N.A.Larsen, P.De Prada, S.X.Deng, A.Mittal, M.Braskett, X.Zhu, I.A.Wilson, D.W.Landry 8067 15209502 Biochemistry Crystallographic and Biochemical Analysis of Cocaine-Degrading Antibody 15A10. 43 2004
1GIG T.Bizebard, R.Daniels, R.Kahn, B.Golinellipimpaneau, J.J.Skehel, M.Knossow 768 n/a Acta Crystallogr D Biol Crystallogr REFINED 3-DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A MURINE IGG1,LAMBDA ANTIBODY. 50 1994
2VIS D.Fleury, S.A.Wharton, J.J.Skehel, M.Knossow, T.Bizebard 119 9461077 Nat Struct Biol Antigen distortion allows influenza virus to escape neutralization. 5 1998
2VIT D.Fleury, S.A.Wharton, J.J.Skehel, M.Knossow, T.Bizebard 119 9461077 Nat Struct Biol Antigen distortion allows influenza virus to escape neutralization. 5 1998
2VIR D.Fleury, S.A.Wharton, J.J.Skehel, M.Knossow, T.Bizebard 119 9461077 Nat Struct Biol Antigen distortion allows influenza virus to escape neutralization. 5 1998
1F4Y S.Villeneuve, H.Souchon, M.M.Riottot, J.C.Mazie, P.S.Lei, C.P.J.Glaudemans, P.Kovac, J.M.Fournier, P.M.Alzari 8433 10880560 Proc.Nat.Acad.Sci.USA Crystal Structure of an Anti-Carbohydrate Antibody Directed Against Vibrio Cholerae O1 in Complex with Antigen: Molecular Basis for Serotype Specificity 97 2000
1MFC A.Zdanov, Y.Li, D.R.Bundle, M.Cygler n/a n/a To be Published High Resolution Structures of Antibody Fab Fragment Complexed with Cell- Surface Oligosaccharide of Pathogenic Salmonella n/a n/a
1NC4 T.M.Corneillie, A.J.Fisher, C.F.Meares 15039 n/a J.Am.Chem.Soc. Crystal Structures of Two Complexes of the Rare-Earth-Dota-Binding Antibody 2D12.5: Ligand Generality from a Chiral System 125 2003
1MFE M.Cygler, D.R.Rose, D.R.Bundle 442 1713710 Science Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment. 253 1991
1MFD D.R.Bundle, H.Baumann, J.R.Brisson, S.M.Gagne, A.Zdanov, M.Cygler 5183 8172893 Biochemistry Solution structure of a trisaccharide-antibody complex: comparison of NMR measurements with a crystal structure. 33 1994
1MFB A.Zdanov, Y.Li, D.R.Bundle, M.Cygler n/a n/a To be Published High Resolution Structures of Antibody Fab Fragment Complexed with Cell- Surface Oligosaccharide of Pathogenic Salmonella n/a n/a
1NC2 T.M.Corneillie, A.J.Fisher, C.F.Meares 15039 n/a J.Am.Chem.Soc. Crystal Structures of Two Complexes of the Rare-Earth-Dota-Binding Antibody 2D12.5: Ligand Generality from a Chiral System 125 2003
1NGQ R.Mizutani, K.Miura, T.Nakayama, I.Shimada, Y.Arata, Y.Satow 208 7490744 J Mol Biol Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate. 254 1995
1NGP R.Mizutani, K.Miura, T.Nakayama, I.Shimada, Y.Arata, Y.Satow 208 7490744 J Mol Biol Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate. 254 1995
1F4X S.Villeneuve, H.Souchon, M.M.Riottot, J.C.Mazie, P.S.Lei, C.P.J.Glaudemans, P.Kovac, J.M.Fournier, P.M.Alzari 8433 10880560 Proc.Nat.Acad.Sci.USA Crystal Structure of an Anti-Carbohydrate Antibody Directed Against Vibrio Cholerae O1 in Complex with Antigen: Molecular Basis for Serotype Specificity 97 2000
1F4W S.Villeneuve, H.Souchon, M.M.Riottot, J.C.Mazie, P.S.Lei, C.P.J.Glaudemans, P.Kovac, J.M.Fournier, P.M.Alzari 8433 10880560 Proc.Nat.Acad.Sci.USA Crystal Structure of an Anti-Carbohydrate Antibody Directed Against Vibrio Cholerae O1 in Complex with Antigen: Molecular Basis for Serotype Specificity 97 2000
1RIV E.Pozharski, A.Hewagama, A.Shanafelt, G.Petsko, D.Ringe n/a n/a To be Published Carving a Binding Site: Structural Study of an Anti-Cocaine Antibody in Complex with Three Cocaine Analogs n/a n/a
1QYG E.Pozharski, A.Hewagama, A.Shanafelt, G.Petsko, D.Ringe n/a n/a To be Published Carving a Binding Site: Structural Study of an Anti-Cocaine Antibody in Complex with Three Cocaine Analogs n/a n/a
1RIU E.Pozharski, A.Hewagama, A.Shanafelt, G.Petsko, D.Ringe n/a n/a To be Published Carving a Binding Site: Structural Study of an Anti-Cocaine Antibody in Complex with Three Cocaine Analogs n/a n/a
1Q72 E.Pozharski, A.Moulin, A.Hewagama, A.Shanafelt, G.Petsko, D.Ringe n/a n/a To be Published Diversity in Hapten Recognition: Structural Study of an Anti-Cocaine Antibody M82G2. n/a n/a
1RFD E.Pozharski, A.Hewagama, A.B.Shanafelt, G.Petsko, D.Ringe n/a n/a To be Published Carving a Binding Site: Structural Study of an Anti-Cocaine Antibody in Complex with Three Cocaine Analogs n/a n/a
1JN6 C.Monnet, F.Bettsworth, E.A.Stura, M.-H.Le Du, R.Menez, L.Derrien, S.Zinn-Justin, B.Gilquin, G.Sibai, N.Battail-Poirot, M.Jolivet, A.Menez, M.Arnaud, F.Ducancel, J.B.Charbonnier 699 11812141 J.Mol.Biol. Highly Specific Anti-Estradiol Antibodies: Structural Characterisation and Binding Diversity. 315 2002
1YUH S.C.Yuhasz, C.Parry, M.Strand, L.M.Amzel 1143 8544863 Mol Immunol Structural analysis of affinity maturation: the three-dimensional structures of complexes of an anti-nitrophenol antibody. 32 1995
1JNH C.Monnet, F.Bettsworth, E.A.Stura, M.-H.Le Du, R.Menez, L.Derrien, S.Zinn-Justin, B.Gilquin, G.Sibai, N.Battail-Poirot, M.Jolivet, A.Menez, M.Arnaud, F.Ducancel, J.B.Charbonnier 699 11812141 J.Mol.Biol. Highly Specific Anti-Estradiol Antibodies: Structural Characterisation and Binding Diversity. 315 2002
1SM3 P.Dokurno, P.A.Bates, H.A.Band, L.M.D.Stewart, J.M.Lally, J.M.Burchell, J.Taylor-Papadimitriou, D.Snary, M.J.E.Sternberg, P.S.Freemont 713 9826510 J Mol Biol Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition. 284 1998
1PG7 C.Eigenbrot, Y.G.Meng, R.Krishnamurthy, M.T.Lipari, L.Presta, B.Devaux, T.Wong, P.Moran, S.Bullens, D.Kirchhofer 433 12888350 J.Mol.Biol. Structural Insight Into How an Anti-Idiotypic Antibody Against D3H44 (Anti-Tissue Factor Antibody) Restores Normal Coagulation. 331 2003
1PFC S.H.Bryant, L.M.Amzel, R.P.Phizackerley, R.J.Poljak 362 n/a Acta Crystallogr B MOLECULAR-REPLACEMENT STRUCTURE OF GUINEA-PIG IGG1 PFC' REFINED AT 3.1A RESOLUTION. 41 1985
1Q0X E.Pozharski, M.A.Wilson, A.Hewagama, A.B.Shanafelt, G.Petsko, D.Ringe 691 15019787 J.Mol.Biol. Anchoring a Cationic Ligand: The Structure of the Fab Fragment of the Anti-Morphine Antibody 9B1 and its Complex with Morphine 337 2004
1Q0Y E.Pozharski, M.A.Wilson, A.Hewagama, A.B.Shanafelt, G.Petsko, D.Ringe 691 15019787 J.Mol.Biol. Anchoring a Cationic Ligand: The Structure of the Fab Fragment of the Anti-Morphine Antibody 9B1 and its Complex with Morphine 337 2004
1GPO W.Schiweck, A.Skerra 934 9180382 J Mol Biol The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment. 268 1997
2IFF S.Chacko, E.Silverton, L.Kam-Morgan, S.Smith-Gill, G.Cohen, D.Davies 261 7531245 J Mol Biol Structure of an antibody-lysozyme complex unexpected effect of conservative mutation. 245 1995
1P2C A.Cauerhff, F.A.Goldbaum, B.C.Braden 3539 14988501 Proc.Nat.Acad.Sci.USA Structural Mechanism for Affinity Maturation of an Anti-Lysozyme Antibody. 101 2004
3HFL G.H.Cohen, S.Sheriff, D.R.Davies 315 n/a Acta Crystallogr D Biol Crystallogr Refined structure of the monoclonal antibody HyHEL-5 with its antigen hen egg-white lysozyme. 52 1996
1BQL S.Chacko, E.Silverton, K.Hibbits, A.Xavier, R.Willson, D.Davies n/a n/a To be Published Structure of an Anti-Hel Fab Fragment Complexed with Bobwhite Quail Lysozyme n/a n/a
1MLC B.C.Braden, H.Souchon, J.L.Eisele, G.A.Bentley, T.N.Bhat, J.Navaza, R.J.Poljak 767 7966295 J Mol Biol Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1. 243 1994
1MLB B.C.Braden, H.Souchon, J.L.Eisele, G.A.Bentley, T.N.Bhat, J.Navaza, R.J.Poljak 767 7966295 J Mol Biol Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1. 243 1994
1ETZ L.W.Guddat, L.Shan, C.Broomell, P.A.Ramsland, Z.Fan, J.M.Anchin, D.S.Linthicum, A.B.Edmundson 853 10993728 J.Mol.Biol. The Three-Dimensional Structure of a Complex of a Murine Fab (Nc10.14) With a Potent Sweetener (Nc174): An Illustration of Structural Diversity in Antigen Recognition by Immunoglobulins 302 2000
1EAP G.W.Zhou, J.Guo, W.Huang, R.J.Fletterick, T.S.Scanlan 1059 8066444 Science Crystal structure of a catalytic antibody with a serine protease active site. 265 1994
1AY1 R.Murali, M.Helmer-Citterich, D.J.Sharkey, E.R.Scalice, J.L.Daiss, M.A.Sullivan, H.M.Krishna Murthy 79 9605541 Protein Eng Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. 11 1998
1BGX R.Murali, D.J.Sharkey, J.L.Daiss, H.M.Murthy 12562 9770525 Proc Natl Acad Sci U S A Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. 95 1998
1KCU D.T.Nair, K.Singh, Z.Siddiqui, B.P.Nayak, K.V.S.Rao, D.M.Salunke 2371 11859128 J.Immunol. Epitope Recognition by Diverse Antibodies Suggests Conformational Convergence in an Antibody Response 168 2002
1KC5 D.T.Nair, K.Singh, Z.Siddiqui, B.P.Nayak, K.V.Rao, D.M.Salunke 2371 11859128 J.Immunol. Epitope Recognition by Diverse Antibodies Suggests Conformational Convergence in an Antibody Response 168 2002
1MRD P.R.Pokkuluri, F.Bouthillier, Y.Li, A.Kuderova, J.Lee, M.Cygler 283 7523684 J Mol Biol Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes. 243 1994
1MRE P.R.Pokkuluri, F.Bouthillier, Y.Li, A.Kuderova, J.Lee, M.Cygler 283 7523684 J Mol Biol Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes. 243 1994
1MRC P.R.Pokkuluri, F.Bouthillier, Y.Li, A.Kuderova, J.Lee, M.Cygler 283 7523684 J Mol Biol Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes. 243 1994
1MRF P.R.Pokkuluri, F.Bouthillier, Y.Li, A.Kuderova, J.Lee, M.Cygler 283 7523684 J Mol Biol Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes. 243 1994
2FBJ T.N.Bhat, E.A.Padlan, D.R.Davies n/a n/a To be Published Refined Crystal Structure of the Galactan-Binding Immunoglobulin Fab J539 at 1.95-Angstroms Resolution n/a n/a
1CIC G.A.Bentley, G.Boulot, M.M.Riottot, R.J.Poljak 254 1700305 Nature Three-dimensional structure of an idiotope-anti-idiotope complex. 348 1990
1L8J V.Oganesyan, N.Oganesyan, S.Terzyan, Q.Dongfeng, Z.Dauter, N.L.Esmon, C.T.Esmon 24851 12034704 J.Biol.Chem. The Crystal Structure of the Endothelial Protein C Receptor and a Bound Phospholipid 277 2002
1LQV V.Oganesyan, N.Oganesyan, S.Terzyan, D.Qu, Z.Dauter, N.L.Esmon, C.T.Esmon 24851 12034704 J.Biol.Chem. The Crystal Structure of the Endothelial Protein C Receptor and a Bound Phospholipid 277 2002
1FSK O.Mirza, A.Henriksen, H.Ipsen, J.Larsen, M.Wissenbach, M.Spangfort, M.Gajhede 331 10861069 J.Immunol. Dominant Epitopes and Allergic Cross-Reactivity: Complex Formation between a Fab Fragment of a Monoclonal Murine Igg Antibody and the Major Allergen from Birch Pollen Bet V 1 165 2000
1RIH U.Krengel, L.-L.Olsson, A.Talavera, G.Rojas, E.Mier, E.Moreno 5597 14627696 J.Biol.Chem. Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl Gm3. 279 2004
1HQ4 C.M.Paschall n/a n/a Thesis Polyene Cyclization Reactions n/a 2000
1CF8 C.M.Paschall, J.Hasserodt, T.Jones, R.A.Lerner, K.D.Janda, D.W.Christianson 1743 n/a Angew.Chem.Intern.Edition Convergence of Catalytic Antibody and Terpene Cyclase Mechanisms: Polyene Cyclization Directed by Carbocation-Pi Interactions 38 1999
1F8T A.V.Fokin, P.V.Afonin, I.I.Mikhailova, I.N.Tsygannik, T.I.Mareeva, V.A.Nesmeianov, W.Pangborn, N.Lee, W.Duax, E.Siszak, V.Z.Pletnev 571 11040993 Bioorg.Khim. Three-Dimensional Structure of Antigen Binding Fragment of Monoclonal Antibody Against Human Interleukin-2 in Two Crystal Forms at 2.2 And 2.9 A Resolution 26 2000
1S5I V.Z.Pletnev, E.A.Goryacheva, I.N.Tsygannik, V.A.Nesmeyanov, S.V.Pletnev, W.Pangborn, W.Duax n/a n/a To be Published The Three-Dimentional Structure of the Fab-Fragment of Monoclonal Antibody to Human Interleukin-2 in the New Crystal Form at 2.7A Resolution n/a n/a
1NLD C.Davies, J.C.Beauchamp, D.Emery, A.Rawas, H.Muirhead 186 n/a Acta Crystallogr D Biol Crystallogr Structure of the Fab fragment from a neutralizing monoclonal antibody directed against an epitope of gp41 from HIV-1. 53 1997
1MIE S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1MJ7 S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1F90 P.V.Afonin, A.V.Fokin, I.N.Tsigannik, I.Y.Mikhailova, L.V.Onoprienko, I.I.Mikhaleva, V.T.Ivanov, T.Y.Mareeva, V.A.Nesmeyanov, N.Li, W.A.Pangborn, W.L.Duax, V.Z.Pletnev 1514 11468348 Protein Sci. Crystal Structure of an Anti-Interleukin 2 Monoclonal Antibody Fab Complexed with an Antigenic Nonapeptide. 10 2001
7FAB F.A.Saul, R.J.Poljak 363 1438175 Proteins Crystal structure of human immunoglobulin fragment Fab New refined at 2.0 A resolution. 14 1992
1BOG T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. 91 1997
1MPA J.M.van den Elsen, J.N.Herron, P.Hoogerhout, J.T.Poolman, E.Boel, T.Logtenberg, J.Wilting, D.J.Crommelin, J.Kroon, P.Gros 113 9294871 Proteins Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide. 29 1997
2MPA J.M.H.Van Den Elsen, J.N.Herron, P.Hoogerhout, J.T.Poolman, E.Boel, T.Logtenberg, J.Wilting, D.J.A.Crommelin, J.Kroon, P.Gros 113 9294871 Proteins: Struct., Funct., Genet. Bactericidal Antibody Recognition of a Pora Epitope of Neisseria Meningitidis: Crystal Structure of a Fab Fragment in Complex with a Fluorescein-Conjugated Peptide 29 1997
1AE6 M.J.Banfield, D.J.King, A.Mountain, R.L.Brady 161 9329081 Proteins VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. 29 1997
1MNU J.van den Elsen, L.Vandeputte-Rutten, J.Kroon, P.Gros 1495 9880525 J Biol Chem Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures. 274 1999
1S5H M.Zhou, R.Mackinnon 839 15099749 J.Mol.Biol. A Mutant Kcsa K(+) Channel with Altered Conduction Properties and Selectivity Filter Ion Distribution. 338 2004
1K4D Y.Zhou, J.H.Morais-Cabral, A.Kaufman, R.Mackinnon 43 11689936 Nature Chemistry of Ion Coordination and Hydration Revealed by a K+ Channel-Fab Complex at 2.0 A Resolution 414 2001
1R3L Y.Zhou, R.Mackinnon 965 14583193 J.Mol.Biol. The Occupancy of Ions in the K+ Selectivity Filter: Charge Balance and Coupling of Ion Binding to a Protein Conformational Change Underlie High Conduction Rates 333 2003
1R3I Y.Zhou, R.Mackinnon 965 14583193 J.Mol.Biol. The Occupancy of Ions in the K+ Selectivity Filter: Charge Balance and Coupling of Ion Binding to a Protein Conformational Change Underlie High Conduction Rates 333 2003
1K4C Y.Zhou, J.H.Morais-Cabral, A.Kaufman, R.Mackinnon 43 11689936 Nature Chemistry of Ion Coordination and Hydration Revealed by a K+ Channel-Fab Complex at 2.0 A Resolution 414 2001
1R3K Y.Zhou, R.Mackinnon 965 14583193 J.Mol.Biol. The Occupancy of Ions in the K+ Selectivity Filter: Charge Balance and Coupling of Ion Binding to a Protein Conformational Change Underlie High Conduction Rates 333 2003
1R3J Y.Zhou, R.Mackinnon 965 14583193 J.Mol.Biol. The Occupancy of Ions in the K+ Selectivity Filter: Charge Balance and Coupling of Ion Binding to a Protein Conformational Change Underlie High Conduction Rates 333 2003
1FJ1 W.Ding, X.Huang, X.Yang, J.J.Dunn, B.J.Luft, S.Koide, C.L.Lawson 1153 11183781 J.Mol.Biol. Structural Identification of a Key Protective B-Cell Epitope in Lyme Disease Antigen Ospa 302 2000
1UB6 A.B.Beuscher, P.Wirsching, R.A.Lerner, K.Janda, R.C.Stevens n/a n/a To be Published Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures n/a n/a
1IGY L.J.Harris, E.Skaletsky, A.McPherson 861 9480774 J Mol Biol Crystallographic structure of an intact IgG1 monoclonal antibody. 275 1998
1FL3 A.Simeonov, M.Matsushita, E.A.Juban, E.H.Thompson, T.Z.Hoffmann, A.E.Beuscher Iv, M.J.Taylor, P.Wirsching, W.Rettig, J.K.Mccusker, R.C.Stevens, D.P.Millar, P.G.Schultz, R.A.Lerner, K.D.Janda 307 11030644 Science Blue-Fluorescent Antibodies 290 2000
1CBV J.N.Herron, X.M.He, D.W.Ballard, P.R.Blier, P.E.Pace, A.L.Bothwell, E.W.Voss Jr., A.B.Edmundson 159 1749770 Proteins An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex. 11 1991
1NBV J.N.Herron, X.M.He, D.W.Ballard, P.R.Blier, P.E.Pace, A.L.Bothwell, E.W.Voss Jr., A.B.Edmundson 159 1749770 Proteins An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex. 11 1991
1Q9W H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1MH5 S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1Q9L H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1MJJ S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1MJU S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1Q9Q H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1Q9K H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1Q9O H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1MJ8 S.N.Ruzheinikov, T.A.Muranova, S.E.Sedelnikova, L.J.Partridge, G.M.Blackburn, I.A.Murray, H.Kakinuma, N.Takashi, K.Shimazaki, J.Sun, Y.Nishi, D.W.Rice 423 12948492 J.Mol.Biol. High-Resolution Crystal Structure of the Fab-Fragments of a Family of Mouse Catalytic Antibodies with Esterase Activity 332 2003
1Q9T H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1Q9R H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1Q9V H.P.Nguyen, N.O.Seto, C.R.Mackenzie, L.Brade, P.Kosma, H.Brade, S.V.Evans 1019 14625588 Nat.Struct.Biol. Germline Antibody Recognition of Distinct Carbohydrate Epitopes. 10 2003
1QGC E.A.Hewat, N.Verdaguer, I.Fita, W.Blakemore, S.Brookes, A.King, J.Newman, E.Domingo, M.G.Mateu, D.I.Stuart 1492 9130694 Embo J. Structure of the Complex of an Fab Fragment of a Neutralizing Antibody with Foot-and-Mouth Disease Virus: Positioning of a Highly Mobile Antigenic Loop 16 1997
1FH5 J.G.Augustine, A.De La Calle, G.Knarr, J.Buchner, C.A.Frederick 3287 11036070 J.Biol.Chem. The Crystal Structure of the Fab Fragment of the Monoclonal Antibody Mak33. Implications for Folding and Interaction with the Chaperone Bip 276 2001
1CFN T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. 91 1997
1HH6 U.Hoffmuller, T.Knaute, M.Hahn, W.Hohne, J.Schneider-Mergener, A.Kramer 4866 10990450 Embo J. Evolutionary Transition Pathways for Changing Peptide Ligand Specificity and Structure 19 2000
1CFT T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. 91 1997
1CFS T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. 91 1997
1HI6 T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell(Cambridge,Mass.) Crystallographic Analysis of Anti-P24 (HIV-1) Monoclonal Antibody Cross-Reactivity and Polyspecificity 91 1997
1HH9 U.Hoffmuller, T.Knaute, M.Hahn, W.Hohne, J.Schneider-Mergener, A.Kramer 4866 10990450 Embo J. Evolutionary Transition Pathways for Changing Peptide Ligand Specificity and Structure 19 2000
1CFQ T.Keitel, A.Kramer, H.Wessner, C.Scholz, J.Schneider-Mergener, W.Hohne 811 9413990 Cell Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. 91 1997
1MCW K.R.Ely, J.N.Herron, A.B.Edmundson 101 2108322 Mol Immunol Three-dimensional structure of a hybrid light chain dimer: protein engineering of a binding cavity. 27 1990
1KFA T.Murata, S.Fushinobu, M.Nakajima, O.Asami, T.Sassa, T.Wakagi, I.Yamaguchi 489 12054627 Biochem.Biophys.Res.Comm. Crystal Structure of the Liganded Anti-Gibberellin A(4) Antibody 4-B8(8)/E9 Fab Fragment 293 2002
1CLO M.J.Banfield, D.J.King, A.Mountain, R.L.Brady 161 9329081 Proteins VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. 29 1997
1DQQ Y.Li, H.Li, S.J.Smith-Gill, R.A.Mariuzza 6296 10828942 Biochemistry Three-Dimensional Structures of the Free and Antigen-Bound Fab from Monoclonal Antilysozyme Antibody Hyhel-63 39 2000
1BFO G.M.Cheetham, G.Hale, H.Waldmann, A.C.Bloomer 85 9811544 J Mol Biol Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart. 284 1998
3HFM E.A.Padlan, E.W.Silverton, S.Sheriff, G.H.Cohen, S.J.Smith-Gill, D.R.Davies 5938 2762305 Proc Natl Acad Sci U S A Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex. 86 1989
1NBY Y.Li, M.Urrutia, S.J.Smith-Gill, R.A.Mariuzza 11 12515535 Biochemistry Dissection of Binding Interactions in the Complex between the Anti-Lysozyme Antibody Hyhel-63 and its Antigen 42 2003
1OPG R.Kodandapani, B.Veerapandian, T.J.Kunicki, K.R.Ely 2268 7836460 J Biol Chem Crystal structure of the OPG2 Fab. An antireceptor antibody that mimics an RGD cell adhesion site. 270 1995
1BM3 R.Kodandapani, L.Veerapandian, C.Z.Ni, C.K.Chiou, R.M.Whittal, T.J.Kunicki, K.R.Ely 61 9790907 Biochem Biophys Res Commun Conformational change in an anti-integrin antibody: structure of OPG2 Fab bound to a beta 3 peptide. 251 1998
1NDG Y.Li, H.Li, F.Yang, S.J.Smith-Gill, R.A.Mariuzza 482 12740607 Nat.Struct.Biol. X-Ray Snapshots of the Maturation of an Antibody Response to a Protein Antigen 10 2003
1DQJ Y.Li, H.Li, S.J.Smith-Gill, R.A.Mariuzza 6296 10828942 Biochemistry Three-Dimensional Structure of the Free and Antigen-Bound Fab from Monoclonal Antilysozyme Antibody Hyhel-63 39 2000
1NDM Y.Li, H.Li, F.Yang, S.J.Smith-Gill, R.A.Mariuzza 482 12740607 Nat.Struct.Biol. X-Ray Snapshots of the Maturation of an Antibody Response to a Protein Antigen 10 2003
1NBZ Y.Li, M.Urrutia, S.J.Smith-Gill, R.A.Mariuzza 11 12515535 Biochemistry Dissection of Binding Interactions in the Complex between the Anti-Lysozyme Antibody Hyhel-63 and its Antigen 42 2003
1DQM Y.Li, H.Li, S.J.Smith-Gill, R.A.Mariuzza 6296 10828942 Biochemistry Three-Dimensional Structures of the Free and Antigen-Bound Fab from Monoclonal Antilysozyme Antibody Hyhel-63 39 2000
1LO4 M.Hugot, N.Bensel, M.Vogel, M.T.Reymond, B.Stadler, J.L.Reymond, U.Baumann 9674 12093912 Proc.Nat.Acad.Sci.USA A Structural Basis for the Activity of Retro-Diels-Alder Catalytic Antibodies: Evidence for a Catalytic Aromatic Residue 99 2002
2CGR L.W.Guddat, L.Shan, J.M.Anchin, D.S.Linthicum, A.B.Edmundson 247 7893280 J Mol Biol Local and transmitted conformational changes on complexation of an anti-sweetener Fab. 236 1994
1CGS L.W.Guddat, L.Shan, J.M.Anchin, D.S.Linthicum, A.B.Edmundson 247 7893280 J Mol Biol Local and transmitted conformational changes on complexation of an anti-sweetener Fab. 236 1994
1KCR D.T.Nair, K.Singh, N.Sahu, K.V.S.Rao, D.M.Salunke 6949 11120821 J.Immunol. Crystal Structure of an Antibody Bound to an Immunodominant Peptide Epitope: Novel Features in Peptide-Antibody Recognition 165 2000
1IAI N.Ban, C.Escobar, R.Garcia, K.Hasel, J.Day, A.Greenwood, A.McPherson 1604 8127852 Proc Natl Acad Sci U S A Crystal structure of an idiotype-anti-idiotype Fab complex. 91 1994
1AIF N.Ban, C.Escobar, K.W.Hasel, J.Day, A.Greenwood, A.McPherson 107 7821749 FASEB J Structure of an anti-idiotypic Fab against feline peritonitis virus-neutralizing antibody and a comparison with the complexed Fab. 9 1995
1A3L A.Heine, E.A.Stura, J.T.Yli-Kauhaluoma, C.Gao, Q.Deng, B.R.Beno, K.N.Houk, K.D.Janda, I.A.Wilson 1934 9506943 Science An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. 279 1998
1RUQ X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1RUR X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1A5F A.Rodriguez-Romero, O.Almog, M.Tordova, Z.Randhawa, G.L.Gilliland 11770 9565600 J Biol Chem Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells. 273 1998
1A3R J.Tormo, D.Blaas, N.R.Parry, D.Rowlands, D.Stuart, I.Fita 2247 8194515 EMBO J Crystal structure of a human rhinovirus neutralizing antibody complexed with a peptide derived from viral capsid protein VP2. 13 1994
1BBD J.Tormo, E.Stadler, T.Skern, H.Auer, O.Kanzler, C.Betzel, D.Blaas, I.Fita 1154 1338980 Protein Sci Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2. 1 1992
1E6J S.Monaco-Malbet, C.Berthet-Colominas, A.Novelli, N.Battai, N.Piga, V.Cheynet, F.Mallet, S.Cusack 1069 n/a Structure Fold.Des. Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24 8 2000
1E6O S.Monaco-Malbet, C.Berthet-Colominas, A.Novelli, N.Battai, N.Piga, V.Cheynet, F.Mallet, S.Cusack 1069 11080628 Structure Fold.Des. Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24 8 2000
1KEN C.Barbey-Martin, B.Gigant, T.Bizebard, L.J.Calder, S.A.Wharton, J.J.Skehel, M.Knossow 70 11886266 Virology An Antibody that Prevents the Hemagglutinin Low Ph Fusogenic Transition 294 2002
1UB5 A.B.Beuscher, P.Wirsching, R.A.Lerner, K.Janda, R.C.Stevens n/a n/a To be Published Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures n/a n/a
12E8 S.Trakhanov, S.Parkin, R.Raffai, R.Milne, Y.M.Newhouse, K.H.Weisgraber, B.Rupp 122 10089402 Acta Crystallogr D Biol Crystallogr Structure of a monoclonal 2E8 Fab antibody fragment specific for the low-density lipoprotein-receptor binding region of apolipoprotein E refined at 1.9 A. 0 1999
1C12 A.C.Langedijk, S.Spinelli, C.Anguille, P.Hermans, J.Nederlof, J.Butenandt, A.Honegger, C.Cambillau, A.Pluckthun 855 10525411 J.Mol.Biol. Insight in Odorant Perception: The Crystal Structure and Binding Characteristics of Antibody Fragments Directed Against the Musk Odorant Traseolide 292 1999
3CK0 Y.H.Pan, K.H.Lee, M.Li, P.Ronco, L.M.Amzel n/a n/a To be Published Structures of Angiotensin II and a Phage-Display Selected Cyclic Peptide in Complex with Fab131: Making Angiotensin II Analogs n/a n/a
1CK0 Y.H.Pan, K.H.Lee, M.Li, P.Ronco, L.M.Amzel n/a n/a To be Published Structures of Angiotensin II and a Phage-Display Selected Cyclic Peptide in Complex with Fab131: Making Angiotensin II Analogs n/a n/a
2CK0 Y.H.Pan, K.H.Lee, M.Li, P.Ronco, L.M.Amzel n/a n/a To be Published Structures of Angiotensin II and a Phage-Display Selected Cyclic Peptide in Complex with Fab131: Making Angiotensin II Analogs n/a n/a
1KEM L.C.Hsieh-Wilson, P.G.Schultz, R.C.Stevens 5363 8643580 Proc Natl Acad Sci U S A Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution. 93 1996
1KEL L.C.Hsieh-Wilson, P.G.Schultz, R.C.Stevens 5363 8643580 Proc Natl Acad Sci U S A Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution. 93 1996
1RU9 X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
4FAB J.N.Herron, X.M.He, M.L.Mason, E.W.Voss Jr., A.B.Edmundson 271 2508085 Proteins Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol. 5 1989
1RUL X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1RUA X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1FLR M.Whitlow, A.J.Howard, J.F.Wood, E.W.Voss, K.D.Hardman 749 n/a Protein Eng 1.85-ANGSTROM STRUCTURE OF ANTIFLUORESCEIN 4-4-20-FAB. 8 1995
1RUM X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1I1C W.L.Martin, A.P.West Jr., L.Gan, P.J.Bjorkman 867 11336709 Mol. Cell Crystal Structure at 2.8A of an Fcrn/Heterodimeric Fc Complex: Mechanism of Ph-Dependent Binding. 7 2001
1H3P J.C.Pizarro, B.Vulliez-Le-Normand, M.M.Riottot, A.Budkowska, G.A.Bentley 463 n/a FEBS Lett. Structural and Functional Characterisation of a Monoclonal Antibody Specific for the Pres1 Region of Hepatitis B Virus 509 2001
1JNL C.Monnet, F.Bettsworth, E.A.Stura, M.-H.Le Du, R.Menez, L.Derrien, S.Zinn-Justin, B.Gilquin, G.Sibai, N.Battail-Poirot, M.Jolivet, A.Menez, M.Arnaud, F.Ducancel, J.B.Charbonnier 699 11812141 J.Mol.Biol. Highly Specific Anti-Estradiol Antibodies: Structural Characterisation and Binding Diversity. 315 2002
1JNN C.Monnet, F.Bettsworth, E.A.Stura, M.-H.Le Du, R.Menez, L.Derrien, S.Zinn-Justin, B.Gilquin, G.Sibai, N.Battail-Poirot, M.Jolivet, A.Menez, M.Arnaud, F.Ducancel, J.B.Charbonnier 699 11812141 J.Mol.Biol. Highly Specific Anti-Estradiol Antibodies: Structural Characterisation and Binding Diversity. 315 2002
1SY6 L.Kjer-Nielsen, M.A.Dunstone, L.Kostenko, L.K.Ely, T.Beddoe, N.A.Mifsud, A.W.Purcell, A.G.Brooks, J.Mccluskey, J.Rossjohn 7675 15136729 Proc.Nat.Acad.Sci.USA Crystal Structure of the Human T Cell Receptor Cd3(Epsilon)(Gamma) Heterodimer Complexed to the Therapeutic Mab Okt3. 101 2004
1A8J A.B.Edmundson, C.V.Manion 580 9630831 Clin Pharmacol Ther Treatment of osteoarthritis with aspartame. 63 1998
1MCN A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCR A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCE A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
4BJL D.B.Huang, C.F.Ainsworth, F.J.Stevens, M.Schiffer 7017 8692936 Proc Natl Acad Sci U S A Three quaternary structures for a single protein. 93 1996
1MCS A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCB A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1DCL K.R.Ely, J.N.Herron, M.Harker, A.B.Edmundson 601 2515285 J Mol Biol Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms. 210 1989
1MCH A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1BJM D.B.Huang, C.F.Ainsworth, F.J.Stevens, M.Schiffer 7017 8692936 Proc Natl Acad Sci U S A Three quaternary structures for a single protein. 93 1996
1MCJ A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCD A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCQ A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCI A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
3MCG K.R.Ely, J.N.Herron, M.Harker, A.B.Edmundson 601 2515285 J Mol Biol Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms. 210 1989
1MCL A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
3BJL D.B.Huang, C.F.Ainsworth, F.J.Stevens, M.Schiffer 7017 8692936 Proc Natl Acad Sci U S A Three quaternary structures for a single protein. 93 1996
1MCF A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCK A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
1MCC A.B.Edmundson, D.L.Harris, Z.C.Fan, L.W.Guddat, B.T.Schley, B.L.Hanson, G.Tribbick, H.M.Geysen 246 8346191 Proteins Principles and pitfalls in designing site-directed peptide ligands. 16 1993
2MCG K.R.Ely, J.N.Herron, M.Harker, A.B.Edmundson 601 2515285 J Mol Biol Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms. 210 1989
2FB4 H.D.Kratzin, W.Palm, M.Stangel, W.E.Schmidt, J.Friedrich, N.Hilschmann 263 2713105 Biol.Chem.Hoppe-Seyler Die Primaerstruktur Des Kristallisierbaren Monoklonalen Immunoglobulins Igg1 Kol. II. Aminosaeuresequenz Der L-Kette, Lambda-Typ, Subgruppe I (German) 370 1989
1AXT .3.Barbas 3rd, A.Heine, G.Zhong, T.Hoffmann, S.Gramatikova, R.Bjornestedt, B.List, J.Anderson, E.A.Stura, I.A.Wilson, R.A.Lerner 2085 9405338 Science Immune versus natural selection: antibody aldolases with enzymic rates but broader scope. 278 1997
1UZ6 A.M.M.Van Roon, N.S.Pannu, J.P.M.De Vrind, G.A.Van Der Marel, J.H.Van Boom, C.H.Hokke, A.M.Deelder, J.P.Abrahams 1227 n/a Structure Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen 12 2004
1UZ8 A.M.M.Van Roon, N.S.Pannu, J.P.M.De Vrind, G.A.Van Der Marel, J.H.Van Boom, C.H.Hokke, A.M.Deelder, J.P.Abrahams 1227 n/a Structure Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen 12 2004
1T66 S.Terzyan, P.A.Ramsland, E.W.Voss Jr., J.N.Herron, A.B.Edmundson 1141 15178254 J.Mol.Biol. Three-Dimensional Structures of Idiotypically Related Fabs with Intermediate and High Affinity for Fluorescein. 339 2004
1FPT M.W.Wien, D.J.Filman, E.A.Stura, S.Guillot, F.Delpeyroux, R.Crainic, J.M.Hogle 232 7539711 Nat Struct Biol Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope. 2 1995
1TQC F.Eghiaian, J.Grosclaude, S.Lesceu, P.Debey, B.Doublet, E.Treguer, H.Rezaei, M.Knossow 10254 15240887 Proc.Nat.Acad.Sci.USA Insight Into the Prpc-->Prpsc Conversion from the Structures of Antibody-Bound Ovine Prion Scrapie-Susceptibility Variants 101 2004
1TPX F.Eghiaian, J.Grosclaude, S.Lesceu, P.Debey, B.Doublet, E.Treguer, H.Rezaei, M.Knossow 10254 15240887 Proc.Nat.Acad.Sci.USA Insight Into the Prpc-> Prpsc Conversion from the Structures of Antibody-Bound Ovine Prion Scrapie-Susceptibility Variants. 101 2004
1RMF M.J.Jedrzejas, J.Miglietta, J.A.Griffin, M.Luo 380 n/a Acta Crystallogr D Biol Crystallogr STRUCTURE OF A MONOCLONAL ANTI-ICAM-1 ANTIBODY R6.5 FAB FRAGMENT AT 2.8 ANGSTROM RESOLUTION. 51 1995
1TQB F.Eghiaian, J.Grosclaude, S.Lesceu, P.Debey, B.Doublet, E.Treguer, H.Rezaei, M.Knossow 10254 15240887 Proc.Nat.Acad.Sci.USA Insight Into the Prpc-->Prpsc Conversion from the Structures of Antibody-Bound Ovine Prion Scrapie-Susceptibility Variants 101 2004
1TY5 T.Xiao, J.Takagi, B.S.Coller, J.-H.Wang, T.A.Springer 59 15378069 Nature Structural Basis for Allostery in Integrins and Binding to Fibrinogen-Mimetic Therapeutics 432 2004
1TXV T.Xiao, J.Takagi, B.S.Coller, J.-H.Wang, T.A.Springer 59 15378069 Nature Structural Basis for Allostery in Integrins and Binding to Fibrinogen-Mimetic Therapeutics 432 2004
1TY3 T.Xiao, J.Takagi, B.S.Coller, J.-H.Wang, T.A.Springer 59 15378069 Nature Structural Basis for Allostery in Integrins and Binding to Fibrinogen-Mimetic Therapeutics 432 2004
1TY7 T.Xiao, J.Takagi, B.S.Coller, J.-H.Wang, T.A.Springer 59 15378069 Nature Structural Basis for Allostery in Integrins and Binding to Fibrinogen-Mimetic Therapeutics 432 2004
1TY6 T.Xiao, J.Takagi, B.S.Coller, J.-H.Wang, T.A.Springer 59 15378069 Nature Structural Basis for Allostery in Integrins and Binding to Fibrinogen-Mimetic Therapeutics 432 2004
1ND0 X.Zhu, A.Heine, F.Monnat, K.N.Houk, K.D.Janda, I.A.Wilson 69 12742019 J.Mol.Biol. Structural Basis for Antibody Catalysis of a Cationic Cyclization Reaction 329 2003
1IGI P.D.Jeffrey, R.K.Strong, L.C.Sieker, C.Y.Chang, R.L.Campbell, G.A.Petsko, E.Haber, M.N.Margolies, S.Sheriff 10310 8234291 Proc Natl Acad Sci U S A 26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity. 90 1993
1RUP X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1IGJ P.D.Jeffrey, R.K.Strong, L.C.Sieker, C.Y.Chang, R.L.Campbell, G.A.Petsko, E.Haber, M.N.Margolies, S.Sheriff 10310 8234291 Proc Natl Acad Sci U S A 26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity. 90 1993
1NCW X.Zhu, A.Heine, F.Monnat, K.N.Houk, K.D.Janda, I.A.Wilson 69 12742019 J.Mol.Biol. Structural Basis for Antibody Catalysis of a Cationic Cyclization Reaction 329 2003
1RUK X.Zhu, P.Wentworth Jr., A.D.Wentworth, A.Eschenmoser, R.A.Lerner, I.A.Wilson 2247 14982995 Proc.Nat.Acad.Sci.USA Probing the Antibody-Catalyzed Water-Oxidation Pathway at Atomic Resolution. 110 2004
1A6T Z.Che, N.H.Olson, D.Leippe, W.M.Lee, A.G.Mosser, R.R.Rueckert, T.S.Baker, T.J.Smith 4610 9573224 J Virol Antibody-mediated neutralization of human rhinovirus 14 explored by means of cryoelectron microscopy and X-ray crystallography of virus-Fab complexes. 72 1998
1K6Q K.Faelber, R.F.Kelley, D.Kirchhofer, Y.A.Muller n/a n/a To be Published The Crystal Structure of Murine Fab D3 at 2.4 A Resolution in Comparison with the Humanised Fab D3H44 (1.85A) Provides Structural Insight Into the Humanisation Process of the D3 Anti-Tissue Factor Antibody n/a n/a
1GHF N.Ban, J.Day, X.Wang, S.Ferrone, A.McPherson 617 8568901 J Mol Biol Crystal structure of an anti-anti-idiotype shows it to be self-complementary. 255 1996
1CT8 B.Gigant, T.Tsumuraya, I.Fujii, M.Knossow 1385 10574796 Structure (London) Diverse Structural Solutions to Catalysis in a Family of Antibodies 7 1999
1I8M J.J.Tanner, A.A.Komissarov, S.L.Deutscher 807 11733999 J.Mol.Biol. Crystal Structure of an Antigen-Binding Fragment Bound to Single-Stranded DNA 314 2001
1P7K J.P.Schuermann, M.T.Henzl, S.L.Deutscher, J.J.Tanner 269 15340914 Proteins: Struct., Funct., Genet. Structure of an Anti-DNA Fab Complexed with a Non-DNA Ligand Provides Insights Into Cross-Reactivity and Molecular Mimicry. 57 2004
1E4X M.Hahn, D.Winkler, R.Misselwitz, H.Wessner, K.Wlefle, G.Zahn, J.Schneider-Mergener, W.Hoehne n/a n/a To be Published Crossreactive Binding of a Circularized Peptide to an Anti-Tgfalpha Antibody Fab-Fragment n/a n/a
1BAF A.T.Brunger, D.J.Leahy, T.R.Hynes, R.O.Fox 239 1920408 J Mol Biol 2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten. 221 1991
1E4W M.Hahn, D.Winkler, R.Misselwitz, H.Wessner, K.Wlefle, G.Zahn, J.Schneider-Mergener, W.Hoehne n/a n/a To be Published Crossreactive Binding of a Circularized Peptide to an Anti-Tgfalpha Antibody Fab-Fragment n/a n/a
1FIG M.R.Haynes, E.A.Stura, D.Hilvert, I.A.Wilson 646 8303271 Science Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart. 263 1994
3F58 R.Stanfield, E.Cabezas, A.Satterthwait, E.Stura, A.Profy, I.Wilson 131 10368281 Structure Fold Des Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. 7 1999
1EJO W.F.Ochoa, S.G.Kalko, M.G.Mateu, P.Gomes, D.Andreu, E.Domingo, I.Fita, N.Verdaguer 1495 10811933 J.Gen.Virol. A Multiply Substituted G-H Loop from Foot-and-Mouth Disease Virus in Complex with a Neutralizing Antibody: A Role for Water Molecules 81 2000
2F58 R.Stanfield, E.Cabezas, A.Satterthwait, E.Stura, A.Profy, I.Wilson 131 10368281 Structure Fold Des Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. 7 1999
1F58 R.Stanfield, E.Cabezas, A.Satterthwait, E.Stura, A.Profy, I.Wilson 131 10368281 Structure Fold Des Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. 7 1999
1HIL J.M.Rini, U.Schulze-Gahmen, I.A.Wilson 959 1546293 Science Structural evidence for induced fit as a mechanism for antibody-antigen recognition. 255 1992
1AFV C.Momany, L.C.Kovari, A.J.Prongay, W.Keller, R.K.Gitti, B.M.Lee, A.E.Gorbalenya, L.Tong, J.McClure, L.S.Ehrlich, M.F.Summers, C.Carter, M.G.Rossmann 763 8784350 Nat Struct Biol Crystal structure of dimeric HIV-1 capsid protein. 3 1996
1HIM J.M.Rini, U.Schulze-Gahmen, I.A.Wilson 959 1546293 Science Structural evidence for induced fit as a mechanism for antibody-antigen recognition. 255 1992
1HIN J.M.Rini, U.Schulze-Gahmen, I.A.Wilson 959 1546293 Science Structural evidence for induced fit as a mechanism for antibody-antigen recognition. 255 1992
1FRG M.E.Churchill, E.A.Stura, C.Pinilla, J.R.Appel, R.A.Houghten, D.H.Kono, R.S.Balderas, G.G.Fieser, U.Schulze-Gahmen, I.A.Wilson 534 7520084 J Mol Biol Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen. 241 1994
1QFU D.Fleury, B.Barrere, T.Bizebard, R.S.Daniels, J.J.Skehel, M.Knossow 530 10360354 Nat Struct Biol A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. 6 1999
1NSN P.Bossart-Whitaker, C.Y.Chang, J.Novotny, D.C.Benjamin, S.Sheriff 559 7473734 J Mol Biol The crystal structure of the antibody N10-staphylococcal nuclease complex at 2.9 A resolution. 253 1995
1IFH U.Schulze-Gahmen, J.M.Rini, I.A.Wilson 1098 8263915 J Mol Biol Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes. 234 1993
1LO2 M.Hugot, N.Bensel, M.Vogel, M.T.Reymond, B.Stadler, J.L.Reymond, U.Baumann 9674 12093912 Proc.Nat.Acad.Sci.USA A Structural Basis for the Activity of Retro-Diels-Alder Catalytic Antibodies: Evidence for a Catalytic Aromatic Residue 99 2002
1NAK R.L.Stanfield, J.B.Ghiara, E.Ollmann Saphire, A.T.Profy, I.A.Wilson 159 14592768 Virology Recurring Conformation of the Human Immunodeficiency Virus Type 1 Gp120 V3 Loop. 315 2003
1LO3 M.Hugot, N.Bensel, M.Vogel, M.T.Reymond, B.Stadler, J.L.Reymond, U.Baumann 9674 12093912 Proc.Nat.Acad.Sci.USA A Structural Basis for the Activity of Retro-Diels-Alder Catalytic Antibodies: Evidence for a Catalytic Aromatic Residue 99 2002
1LO0 M.Hugot, N.Bensel, M.Vogel, M.T.Reymond, B.Stadler, J.L.Reymond, U.Baumann 9674 12093912 Proc.Nat.Acad.Sci.USA A Structural Basis for the Activity of Retro-Diels-Alder Catalytic Antibodies: Evidence for a Catalytic Aromatic Residue 99 2002
1IL1 M.B.Berry, K.A.Johnson, W.Radding, M.Fung, R.Liou, G.N.Phillips Jr. 281 11599031 Proteins: Struct., Funct., Genet. Structure of an Anti-HIV Monoclonal Fab Antibody Fragment Specific to a Gp120 C-4 Region Peptide 45 2001
1MHH M.Graille, S.Harrison, M.P.Crump, S.C.Findlow, N.G.Housden, B.H.Muller, N.Battail-Poirot, G.Sibai, B.J.Sutton, M.J.Taussig, C.Jolivet-Reynaud, M.G.Gore, E.A.Stura 47500 12221088 J.Biol.Chem. Evidence for Plasticity and Structural Mimicry at the Immunoglobulin Light Chain-Protein L Interface 277 2002
1N64 R.Menez, M.Bossus, B.H.Muller, G.Sibai, P.Dalbon, F.Ducancel, C.Jolivet-Reynaud, E.A.Stura 1917 12574359 J.Immunol. Crystal Structure of a Hydrophobic Immunodominant Antigenic Site on Hepatitis C Virus Core Protein Complexed to Monoclonal Antibody 19D9D6. 170 2003
1JGU N.A.Larsen, A.Heine, L.Crane, B.F.Cravatt, R.A.Lerner, I.A.Wilson 93 11724535 J.Mol.Biol. Structural Basis for a Disfavored Elimination Reaction in Catalytic Antibody 1D4 314 2001
1NLB R.Menez, M.Bossus, B.H.Muller, G.Sibai, P.Dalbon, F.Ducancel, C.Jolivet-Reynaud, E.A.Stura 1917 12574359 J.Immunol. Crystal Structure of a Hydrophobic Immunodominant Antigenic Site on Hepatitis C Virus Core Protein Complexed to Monoclonal Antibody 19D9D6. 170 2003
1JGV N.A.Larsen, A.Heine, L.Crane, B.F.Cravatt, R.A.Lerner, I.A.Wilson 93 11724535 J.Mol.Biol. Structural Basis for a Disfavored Elimination Reaction in Catalytic Antibody 1D4 314 2001
35C8 K.Gruber, B.Zhou, K.N.Houk, R.A.Lerner, C.G.Shevlin, I.A.Wilson 7062 10353817 Biochemistry Structural basis for antibody catalysis of a disfavored ring closure reaction. 38 1999
25C8 K.Gruber, B.Zhou, K.N.Houk, R.A.Lerner, C.G.Shevlin, I.A.Wilson 7062 10353817 Biochemistry Structural basis for antibody catalysis of a disfavored ring closure reaction. 38 1999
1JRH S.Sogabe, F.Stuart, C.Henke, A.Bridges, G.Williams, A.Birch, F.K.Winkler, J.A.Robinson 882 9367779 J Mol Biol Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex. 273 1997
15C8 K.Gruber, A.Heine, E.A.Stura, C.G.Shevlin, I.A.Wilson n/a n/a To be Published Ligand-Induced Conformational Changes in a Catalytic Antibody: Comparison of the Bound and Unbound Structure of Fab 5C8 n/a n/a
1DBJ J.H.Arevalo, M.J.Taussig, I.A.Wilson 859 8413674 Nature Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. 365 1993
1DBA J.H.Arevalo, E.A.Stura, M.J.Taussig, I.A.Wilson 103 8496956 J Mol Biol Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex. 231 1993
1DBB J.H.Arevalo, E.A.Stura, M.J.Taussig, I.A.Wilson 103 8496956 J Mol Biol Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex. 231 1993
1DBM J.H.Arevalo, M.J.Taussig, I.A.Wilson 859 8413674 Nature Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. 365 1993
1DBK J.H.Arevalo, M.J.Taussig, I.A.Wilson 859 8413674 Nature Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. 365 1993
1C1E J.Xu, Q.Deng, J.Chen, K.N.Houk, J.Bartek, D.Hilvert, I.A.Wilson 2345 10600746 Science Evolution of Shape Complementarity and Catalytic Efficiency from a Primordial Antibody Template 286 1999
2DBL J.H.Arevalo, M.J.Taussig, I.A.Wilson 859 8413674 Nature Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. 365 1993
1H0D G.Chavali, A.Papageorgiou, K.Olson, J.Fett, G.Hu, R.Shapiro, K.R.Acharya 875 n/a Structure The Crystal Structure of Human Angiogenin in Complex with an Antitumor Neutralizing Antibody 11 2003
1T4K X.Zhu, F.Tanaka, Y.Hu, A.Heine, R.Fuller, G.Zhong, A.J.Olson, R.A.Lerner, C.F.Barbas, I.A.Wilson 1269 15491612 J.Mol.Biol. The Origin of Enantioselectivity in Aldolase Antibodies: Crystal Structure, Site-Directed Mutagenesis, and Computational Analysis 343 2004
1L7T J.Valjakka, A.Hemminki, S.Niemi, H.Soderlund, K.Takkinen, J.Rouvinen 44021 12196551 J.Biol.Chem. Crystal Structure of an in Vitro Affinity-and Specificity-Matured Anti-Testosterone Fab in Complex with Testosterone. Improved Affinity Results from Small Structural Changes within the Variable Domains 277 2002
1VPO J.M.Valjakka, A.Hemminki, S.Niemi, H.Soderlund, K.Takkinen, J.Rouvinen 44021 12196551 J.Biol.Chem. Crystal Structure of an in Vitro Affinity- and Specificity-Matured Anti-Testosterone Fab in Complex with Testosterone. Improved Affinity Results from Small Structural Changes within the Variable Domains 277 2002
1CLZ P.D.Jeffrey, J.Bajorath, C.Y.Chang, D.Yelton, I.Hellstrom, K.E.Hellstrom, S.Sheriff 466 7664109 Nat Struct Biol The x-ray structure of an anti-tumour antibody in complex with antigen. 2 1995
1OTU R.Dutzler, E.B.Campbell, R.Mackinnon 108 12649487 Science Gating the Selectivity Filter in Clc Chloride Channels 300 2003
1OTS R.Dutzler, E.B.Campbell, R.Mackinnon 108 12649487 Science Gating the Selectivity Filter in Clc Chloride Channels 300 2003
1FE8 R.A.P.Romijn, B.Bouma, W.Wuyster, P.Gros, J.Kroon, J.J.Sixma, E.G.Huizinga 9985 11098050 J.Biol.Chem. Identification of the Collagen-Binding Site of the Von Willebrand Factor A3-Domain 276 2001
1OTT R.Dutzler, E.B.Campbell, R.Mackinnon 108 12649487 Science Gating the Selectivity Filter in Clc Chloride Channels 300 2003
1V7M M.D.Feese, T.Tamada, Y.Kato, Y.Maeda, M.Hirose, Y.Matsukura, H.Shigematsu, T.Muto, A.Matsumoto, H.Watarai, K.Ogami, T.Tahara, T.Kato, H.Miyazaki, R.Kuroki 1816 14769915 Proc.Nat.Acad.Sci.USA Structure of the Receptor-Binding Domain of Human Thrombopoietin Determined by Complexation with a Neutralizing Antibody Fragment 101 2004
1V7N M.D.Feese, T.Tamada, Y.Kato, Y.Maeda, M.Hirose, Y.Matsukura, H.Shigematsu, T.Muto, A.Matsumoto, H.Watarai, K.Ogami, T.Tahara, T.Kato, H.Miyazaki, R.Kuroki 1816 14769915 Proc.Nat.Acad.Sci.USA Structure of the Receptor-Binding Domain of Human Thrombopoietin Determined by Complexation with a Neutralizing Antibody Fragment 101 2004
6FAB R.K.Strong, R.Campbell, D.R.Rose, G.A.Petsko, J.Sharon, M.N.Margolies 3739 2015229 Biochemistry Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36- 71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. 30 1991
1FDL T.O.Fischmann, G.A.Bentley, T.N.Bhat, G.Boulot, R.A.Mariuzza, S.E.Phillips, D.Tello, R.J.Poljak 12915 1712773 J Biol Chem Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution. 266 1991
2F19 M.-B.Lascombe, P.M.Alzari, R.J.Poljak, A.Nisonoff 9429 1409652 Proc.Nat.Acad.Sci.USA Three-Dimensional Structure of Two Crystal Forms of Fab R19.9, From a Monoclonal Anti-Arsonate Antibody 89 1992
1FAI M.B.Lascombe, P.M.Alzari, R.J.Poljak, A.Nisonoff 9429 1409652 Proc Natl Acad Sci U S A Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. 89 1992
1PZ5 N.K.Vyas, M.N.Vyas, M.C.Chervenak, D.R.Bundle, B.M.Pinto, F.A.Quiocho 15023 14645714 Proc.Nat.Acad.Sci.USA Structural Basis of Peptide-Carbohydrate Mimicry in an Antibody Combining Site. 100 2003
1M7I N.K.Vyas, M.N.Vyas, M.C.Chervenak, M.A.Johnson, B.M.Pinto, D.R.Bundle, F.A.Quiocho 13575 12427018 Biochemistry Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella Flexneri Y Lipopolysaccharide: X-Ray Structures and Thermodynamics 41 2002
1M71 N.K.Vyas, M.N.Vyas, M.C.Chervenak, M.A.Johnson, B.M.Pinto, D.R.Bundle, F.A.Quiocho 13575 12427018 Biochemistry Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella Flexneri Y Lipopolysaccharide: X-Ray Structures and Thermodyanamics 41 2002
1M7D N.K.Vyas, M.N.Vyas, M.C.Chervenak, M.A.Johnson, B.M.Pinto, D.R.Bundle, F.A.Quiocho 13575 12427018 Biochemistry Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella Flexneri Y Lipopolysaccharide: X-Ray Structures and Thermodynamics 41 2002
1JFQ B.Parhami-Seren, M.Viswanathan, R.K.Strong, M.N.Margolies 5129 11673524 J.Immunol. Structural Analysis of Mutants of High-Affinity and Low-Affinity P-Azophenylarsonate-Specific Antibodies Generated by Alanine Scanning of Heavy Chain Complementarity-Determining Region 2. 67 2001
1IBG P.D.Jeffrey, J.F.Schildbach, C.Y.Chang, P.H.Kussie, M.N.Margolies, S.Sheriff 344 7739045 J Mol Biol Structure and specificity of the anti-digoxin antibody 40-50. 248 1995
1QKZ J.P.Derrick, I.M.Feavers, M.C.J.Maiden 81 10512717 J.Mol.Biol. Crystal Structure of an Fab Fragment in Complex with a Meningococcal Serosubtype Antigen and a Protein G Domain 293 1999
1IQW S.Ito, T.Takayama, H.Hanzawa, K.Ichikawa, J.Ohsumi, N.Serizawa, T.Hata, H Haruyama 137 11754745 J.Biochem.(Tokyo) Crystal Structure of the Antigen-Binding Fragment of Apoptosis-Inducing Mouse Anti-Human Fas Monoclonal Antibody Hfe7A 131 2002
1F3D B.Golinelli-Pimpaneau, O.Goncalves, T.Dintinger, D.Blanchard, M.Knossow, C.Tellier 9892 10963661 Proc.Nat.Acad.Sci.USA Structural Evidence for a Programmed General Base in the Active Site of a Catalytic Antibody. 97 2000
1SBS C.Fotinou, J.Beauchamp, P.Emsley, A.deHaan, W.J.Schielen, E.Bos, N.W.Isaacs 22515 9712877 J Biol Chem Structure of an Fab fragment against a C-terminal peptide of hCG at 2.0 A resolution. 273 1998
1O0V T.Wan, R.L.Beavil, S.M.Fabiane, A.J.Beavil, M.K.Sohi, M.Keown, R.J.Young, A.J.Henry, R.J.Owens, H.J.Gould, B.J.Sutton 681 12068291 Nat.Immunol. The Crystal Structure of Ige Fc Reveals an Asymmetrically Bent Conformation 3 2002
1R24 M.J.Kaminski, C.R Mackenzie, M.J.Mooibroek, T.E.Dahms, T.Hirama, A.N.Houghton, P.B.Chapman, S.V.Evans 5597 10026176 J.Biol.Chem. The Role of Homophilic Binding in Anti-Tumor Antibody R24 Recognition of Molecular Surfaces. Demonstration of an Intermolecular Beta-Sheet Interaction between Vh Domains 274 1999
1FOR H.Liu, T.J.Smith, W.M.Lee, A.G.Mosser, R.R.Rueckert, N.H.Olson, R.H.Cheng, T.S.Baker 127 8027997 J Mol Biol Structure determination of an Fab fragment that neutralizes human rhinovirus 14 and analysis of the Fab-virus complex. 240 1994
1R0A E.N.Peletskaya, A.A.Kogon, S.Tuske, E.Arnold, S.H.Hughes 3387 15016861 J.Virol. Nonnucleoside Inhibitor Binding Affects the Interactions of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with DNA. 78 2004
1T03 S.Tuske, S.G.Sarafianos, A.D.Clark Jr., J.Ding, L.K.Naeger, K.L.White, M.D.Miller, C.S.Gibbs, P.L.Boyer, P.Clark, G.Wang, B.L.Gaffney, R.A.Jones, D.M.Jerina, S.H.Hughes, E.Arnold 469 15107837 Nat.Struct.Mol.Biol. Structure of HIV-1 RT-DNA Complexes Before and After Incorporation of the Anti-Aids Drug Tenofovir 11 2004
1N6Q S.G.Sarafianos, A.D.Clark Jr., K.Das, S.Tuske, J.J.Birktoft, I.Ilankumaran, A.R.Ramesha, J.M.Sayer, D.M.Jerina, P.L.Boyer, S.H.Hughes, E.Arnold 6614 12456667 Embo J. Structures of HIV-1 Reverse Transcriptase with Pre-and Post-Translocation Aztmp-Terminated DNA 21 2002
1N5Y S.G.Sarafianos, A.D.Clark Jr., K.Das, S.Tuske, J.J.Birktoft, P.Ilankumaran, A.R.Ramesha, J.M.Sayer, D.M.Jerina, P.L.Boyer, S.H.Hughes, E.Arnold 6614 12456667 Embo J. Structure of HIV-1 Reverse Transcriptase with Pre-Translocation and Post-Translocation Aztmp-Terminated DNA 21 2002
1RJL M.Becker, J.Bunikis, B.D.Lade, J.J.Dunn, A.G.Barbour, C.L.Lawson n/a n/a To be Published Structural Investigation of B. Burgdorferi Ospb, a Bactericidal Fab Target n/a n/a
1PSK S.L.Pichla, R.Murali, R.M.Burnett 6 9216084 J Struct Biol The crystal structure of a Fab fragment to the melanoma-associated GD2 ganglioside. 119 1997
1MEX A.Heine, I.A.Wilson n/a n/a To be Published Antibody Catalysis of a Bimolecular Cycloaddition Reaction n/a n/a
1NCD W.R.Tulip, J.N.Varghese, W.G.Laver, R.G.Webster, P.M.Colman 122 1381757 J Mol Biol Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex. 227 1992
1FBI J.Lescar, M.Pellegrini, H.Souchon, D.Tello, R.J.Poljak, N.Peterson, M.Greene, P.M.Alzari 18067 7629116 J Biol Chem Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme. 270 1995
1NCA W.R.Tulip, J.N.Varghese, W.G.Laver, R.G.Webster, P.M.Colman 122 1381757 J Mol Biol Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex. 227 1992
1QBL S.E.Mylvaganam, Y.Paterson, E.D.Getzoff 301 9698550 J Mol Biol Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution. 281 1998
1MAM D.R.Rose, M.Przybylska, R.J.To, C.S.Kayden, R.P.Oomen, E.Vorberg, N.M.Young, D.R.Bundle 1106 8358294 Protein Sci Crystal structure to 2.45 A resolution of a monoclonal Fab specific for the Brucella A cell wall polysaccharide antigen. 2 1993
1WEJ S.E.Mylvaganam, Y.Paterson, E.D.Getzoff 301 9698550 J Mol Biol Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution. 281 1998
1QBM S.E.Mylvaganam, Y.Paterson, E.D.Getzoff 301 9698550 J Mol Biol Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution. 281 1998
1OSP H.Li, J.J.Dunn, B.J.Luft, C.L.Lawson 3584 9108020 Proc Natl Acad Sci U S A Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab. 94 1997
1ORS Y.Jiang, A.Lee, J.Chen, V.Ruta, M.Cadene, B.T.Chait, R.Mackinnon 33 12721618 Nature X-Ray Structure of a Voltage-Dependent K+ Channel 423 2003
1IGT L.J.Harris, S.B.Larson, K.W.Hasel, A.McPherson 1581 9048542 Biochemistry Refined structure of an intact IgG2a monoclonal antibody. 36 1997
1NCC W.R.Tulip, J.N.Varghese, R.G.Webster, W.G.Laver, P.M.Colman 149 1522584 J Mol Biol Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface. 227 1992
1KB5 D.Housset, G.Mazza, C.Gregoire, C.Piras, B.Malissen, J.C.Fontecilla-Camps 4205 9250664 EMBO J The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. 16 1997
1NCB W.R.Tulip, J.N.Varghese, R.G.Webster, W.G.Laver, P.M.Colman 149 1522584 J Mol Biol Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface. 227 1992
1EMT B.C.Braden, F.A.Goldbaum, B.-X.Chen, A.N.Kirschner, S.R.Wilson, B.F.Erlanger 12193 11035793 Proc.Nat.Acad.Sci.USA X-Ray Crystal Structure of an Anti-Buckminsterfullerene Antibody Fab Fragment: Biomolecular Recognition of C60 97 2000
1AI1 J.B.Ghiara, D.C.Ferguson, A.C.Satterthwait, H.J.Dyson, I.A.Wilson 31 9054968 J Mol Biol Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. 266 1997
1MF2 J.Lescar, R.Stouracova, M.M.Riottot, V.Chitarra, J.Brynda, M.Fabry, M.Horejsi, J.Sedlacek, G.A.Bentley 1207 9150407 J Mol Biol Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody. 267 1997
1OB1 J.C.Pizarro, V.Chitarra, D.Verger, I.Holm, S.Petres, S.Dartville, F.Nato, S.Longacre, G.A.Bentley 1091 n/a J.Mol.Biol. Crystal Structure of a Fab Complex Formed with Pfmsp1-19, the C-Terminal Fragment of Merozoite Surface Protein 1 from Plasmodium Falciparum: A Malaria Vaccine Candidate 328 2003
1ACY J.B.Ghiara, E.A.Stura, R.L.Stanfield, A.T.Profy, I.A.Wilson 82 7511253 Science Crystal structure of the principal neutralization site of HIV-1. 264 1994
1ORQ Y.Jiang, A.Lee, J.Chen, V.Ruta, M.Cadene, B.T.Chait, R.Mackinnon 33 12721618 Nature X-Ray Structure of a Voltage-Dependent K+ Channel 423 2003
1GGB R.L.Stanfield, M.Takimoto-Kamimura, J.M.Rini, A.T.Profy, I.A.Wilson 83 8069628 Structure Major antigen-induced domain rearrangements in an antibody. 1 1993
1GGC R.L.Stanfield, M.Takimoto-Kamimura, J.M.Rini, A.T.Profy, I.A.Wilson 83 8069628 Structure Major antigen-induced domain rearrangements in an antibody. 1 1993
1CL7 J.Lescar, J.Brynda, P.Rezacova, R.Stouracova, M.-M.Riottot, V.Chitarra, M.Fabry, M.Horejsi, J.Sedlacek, G.A.Bentley 2686 10631984 Protein Sci. Inhibition of the HIV-1 and HIV-2 Proteases by a Monoclonal Antibody 8 1999
2PCP K.Lim, S.M.Owens, L.Arnold, J.C.Sacchettini, D.S.Linthicum 28576 9786848 J Biol Chem Crystal structure of monoclonal 6B5 Fab complexed with phencyclidine. 273 1998
1HYX O.Kristensen, D.G.Vassylyev, F.Tanaka, K.Morikawa, I.Fujii 501 9698565 J Mol Biol A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution. 281 1998
1HYY O.Kristensen, D.G.Vassylyev, F.Tanaka, K.Morikawa, I.Fujii 501 9698565 J Mol Biol A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution. 281 1998
1KEG H.Yokoyama, R.Mizutani, Y.Satow, K.Sato, Y.Komatsu, E.Ohtsuka, O.Nikaido n/a n/a To be Published Crystal Structure of DNA (6-4) Photoproduct Dtt(6-4)Tt in Complex with the 64M-2 Antibody Fab Fragment Implies Increased Antibody-Binding Affinity by the Flanking Nucleotides n/a n/a
1EHL H.Yokoyama, R.Mizutani, Y.Satow, Y.Komatsu, E.Ohtsuka, O.Nikaido 711 10835279 J.Mol.Biol. Crystal Structure of the 64M-2 Antibody Fab Fragment in Complex with a DNA Dt(6-4)T Photoproduct Formed by Ultraviolet Radiation 299 2000
32C2 M.W.Sawicki, P.C.Ng, B.M.Burkhart, V.Pletnev, T.Higashiyama, Y.Osawa, D.Ghosh 423 10449095 Mol.Immunol. Structure of an Activity Suppressing Fab Fragment to Cytochrome P450 Aromatase: Insights Into the Antibody-Antigen Interactions 36 1999
1F11 F.A.Saul, B.Vulliez-Le Normand, M.Passafiume, M.M.Riottot, G.A.Bentley 945 10944330 Acta Crystallogr., Sect.D Structure of the Fab Fragment from F124, a Monoclonal Antibody Specific for Hepatitis B Surface Antigen 56 2000
1GGI J.M.Rini, R.L.Stanfield, E.A.Stura, P.A.Salinas, A.T.Profy, I.A.Wilson 6325 8327513 Proc Natl Acad Sci U S A Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen. 90 1993
2HRP J.Lescar, R.Stouracova, M.M.Riottot, V.Chitarra, J.Brynda, M.Fabry, M.Horejsi, J.Sedlacek, G.A.Bentley 1207 9150407 J Mol Biol Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody. 267 1997
2IGF R.L.Stanfield, T.M.Fieser, R.A.Lerner, I.A.Wilson 712 2333521 Science Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A. 248 1990
1IGF R.L.Stanfield, T.M.Fieser, R.A.Lerner, I.A.Wilson 712 2333521 Science Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A. 248 1990
1I9J J.Valjakka, K.Takkinenz, T.Teerinen, H.Soderlund, J.Rouvinen 4183 11707437 J.Biol.Chem. Structural Insights Into Steroid Hormone Binding 277 2002
1I9I J.Valjakka, K.Takkinenz, T.Teerinen, H.Soderlund, J.Rouvinen 4183 11707437 J.Biol.Chem. Structural Insights Into Steroid Hormone Binding 277 2002
1MCP Y.Satow, G.H.Cohen, E.A.Padlan, D.R.Davies 593 3097327 J Mol Biol Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A. 190 1986
2MCP E.A.Padlan, G.H.Cohen, D.R.Davies n/a n/a To be Published Refined Crystal Structure of the Mcpc603 Fab-Phosphocholine Complex at 3.1 Angstroms Resolution n/a n/a
1A0Q J.L.Buchbinder, R.C.Stephenson, T.S.Scanlan, R.J.Fletterick 1033 9753552 J Mol Biol A comparison of the crystallographic structures of two catalytic antibodies with esterase activity. 282 1998
1OAK R.Celikel, K.I.Varughese, ?.Madhusudan, A.Yoshioka, J.Ware, Z.M.Ruggeri 189 9501911 Nat Struct Biol Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab. 5 1998
1JGL U.Lamminmaki, J.A.Kankare 36687 11451948 J.Biol.Chem. Crystal Structure of a Recombinant Anti-Estradiol Fab Fragment in Complex with 17Beta-Estradiol 276 2001
1JHK U.Lamminmaki, J.A.Kankare 36687 11451948 J.Biol.Chem. Crystal Structure of a Recombinant Anti-Estradiol Fab Fragment in Complex with 17Beta-Estradiol 276 2001
1FNS R.Celikel, Z.M.Ruggeri, K.I.Varughese 881 11017197 Nat.Struct.Biol. Modulation of Von Willebrand Factor Conformation and Adhesive Function by an Internalized Water Molecule 7 2000
2H1P A.C.M.Young, P.Valadon, A.Casadevall, M.D.Scharff, J.C.Sacchettini 622 9417940 J.Mol.Biol. The Three-Dimensional Structures of a Polysaccharide Binding Antibody to Cryptococcus Neoformans and its Complex with a Peptide from a Phage Display Library: Implications for the Identification of Peptide Mimotopes 274 1997
1DQD L.M.Wright, A.M.Brzozowski, R.E.Hubbard, A.C.W.Pike, S.M.Roberts, R.N.Skovgaard, I.Svendsen, H.Vissing, R.P.Bywater 573 10771426 Acta Crystallogr., Sect.D Structure of Fab Hgr-2 F6, a Competitive Antagonist of the Glucagon Receptor 56 2000
1C5D M.Kontou, D.D.Leonidas, E.H.Vatzaki, P.Tsantili, A.Mamalaki, N.G.Oikonomakos, K.R.Acharya, S.J.Tzartos 2389 10759865 Eur.J.Biochem. The Crystal Structure of the Fab Fragment of a Rat Monoclonal Antibody Against the Main Immunogenic Region of the Human Muscle Acetylcholine Receptor 267 2000
1AHW M.Huang, R.Syed, E.A.Stura, M.J.Stone, R.S.Stefanko, W.Ruf, T.S.Edgington, I.A.Wilson 873 9480775 J Mol Biol The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. 275 1998
1FGN M.Huang, R.Syed, E.A.Stura, M.J.Stone, R.S.Stefanko, W.Ruf, T.S.Edgington, I.A.Wilson 873 9480775 J Mol Biol The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. 275 1998
1PLG S.V.Evans, B.W.Sigurskjold, H.J.Jennings, J.R.Brisson, R.To, W.C.Tse, E.Altman, M.Frosch, C.Weisgerber, H.D.Kratzin, et al. 6737 7538787 Biochemistry Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid. 34 1995
1LK3 K.Josephson, B.C.Jones, L.J.Walter, R.Digiacomo, S.R.Indelicato, M.R.Walter 981 12121653 Structure Noncompetitive Antibody Neutralization of Il-10 Revealed by Protein Engineering and X-Ray Crystallography 10 2002
1EO8 D.Fleury, R.S.Daniels, J.J.Skehel, M.Knossow, T.Bizebard 572 10899782 Proteins: Struct., Funct., Genet. Structural Evidence for Recognition of a Single Epitope by Two Distinct Antibodies 40 2000
1KNO J.B.Charbonnier, E.Carpenter, B.Gigant, B.Golinelli-Pimpaneau, Z.Eshhar, B.S.Green, M.Knossow 11721 8524836 Proc Natl Acad Sci U S A Crystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodies. 92 1995
1LHZ S.S.Terzyan, C.R.Dewitt, P.A.Ramsland, P.C.Bourne, A.B.Edmundson 83 12720277 J.Mol.Recog. Comparison of the Three-Dimensional Structures of a Human Bence-Jones Dimer Crystallized on Earth and Aboard Us Space Shuttle Mission Sts-95 16 2003
1JVK P.C.Bourne, P.A.Ramsland, L.Shan, Z.-C.Fan, C.R.Dewitt, B.B.Shultz, S.S.Terzyan, C.R.Moomaw, C.A.Slaughter, L.W.Guddat, A.B.Edmundson 815 11976493 Acta Crystallogr., Sect.D Three-Dimensional Structure of an Immunoglobulin Light-Chain Dimer with Amyloidogenic Properties 58 2002
1LGV S.S.Terzyan, C.R.Dewitt, P.A.Ramsland, P.C.Bourne, A.B.Edmundson 83 12720277 J.Mol.Recog. Comparison of the Three-Dimensional Structures of a Human Bence-Jones Dimer Crystallized on Earth and Aboard Us Space Shuttle Mission Sts-95 16 2003
1AQK C.Faber, L.Shan, Z.Fan, L.W.Guddat, C.Furebring, M.Ohlin, C.A.Borrebaeck, A.B.Edmundson 253 9530559 Immunotechnology Three-dimensional structure of a human Fab with high affinity for tetanus toxoid. 3 1998
1CR9 Z.F.Kanyo, K.M.Pan, R.A.Williamson, D.R.Burton, S.B.Prusiner, R.J.Fletterick, F.E.Cohen 855 10543972 J.Mol.Biol. Antibody Binding Defines a Structure for an Epitope that Participates in the Prpc-->Prpsc Conformational Change 293 1999
1CU4 Z.F.Kanyo, K.M.Pan, R.A.Williamson, D.R.Burton, S.B.Prusiner, R.J.Fletterick, F.E.Cohen 855 10543972 J.Mol.Biol. Antibody Binding Defines a Structure for an Epitope that Participates in the Prpc-->Prpsc Conformational Change 293 1999
8FAB R.K.Strong, R.Campbell, D.R.Rose, G.A.Petsko, J.Sharon, M.N.Margolies 3739 2015229 Biochemistry Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36- 71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. 30 1991
1IKF D.Altschuh, O.Vix, B.Rees, J.C.Thierry 92 1566062 Science A conformation of cyclosporin A in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex. 256 1992
1YEI B.Gigant, J.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 741 9826512 J Mol Biol Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. 284 1998
1KN4 L.J.D'Souza, B.Gigant, M.Knossow, B.S.Green 2114 11878955 J.Am.Chem.Soc. Remarkable Remote Chiral Recognition in a Reaction Mediated by a Catalytic Antibody 124 2002
1KN2 L.J.D'Souza, B.Gigant, M.Knossow, B.S.Green 2114 11878955 J.Am.Chem.Soc. Remarkable Remote Chiral Recognition in a Reaction Mediated by a Catalytic Antibody 124 2002
1YED J.B.Charbonnier, B.Golinelli-Pimpaneau, B.Gigant, D.S.Tawfik, R.Chap, D.G.Schindler, S.H.Kim, B.S.Green, Z.Eshhar, M.Knossow 1140 9027317 Science Structural convergence in the active sites of a family of catalytic antibodies. 275 1997
1YEK B.Gigant, J.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 741 9826512 J Mol Biol Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. 284 1998
1YEJ B.Gigant, J.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 741 9826512 J Mol Biol Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody. 284 1998
1YEE J.B.Charbonnier, B.Golinelli-Pimpaneau, B.Gigant, D.S.Tawfik, R.Chap, D.G.Schindler, S.H.Kim, B.S.Green, Z.Eshhar, M.Knossow 1140 9027317 Science Structural convergence in the active sites of a family of catalytic antibodies. 275 1997
1Q1J R.L.Stanfield, M.K.Gorny, C.Williams, S.Zolla-Pazner, I.A.Wilson 193 n/a Structure Structural Rationale for the Broad Neutralization of HIV-1 by Human Monoclonal Antibody 447-52D 12 2004
1NL0 M.Huang, B.C.Furie, B.Furie 14338 14722079 J.Biol.Chem. Crystal Structure of the Calcium-Stabilized Human Factor Ix Gla Domain Bound to a Conformation-Specific Anti-Factor Ix Antibody. 279 2004
1KCV D.T.Nair, K.Singh, Z.Siddiqui, B.P.Nayak, K.V.S.Rao, D.M.Salunke 2371 11859128 J.Immunol. Epitope Recognition by Diverse Antibodies Suggests Conformational Convergence in an Antibody Response 168 2002
1KCS D.T.Nair, K.Singh, Z.Siddiqui, B.P.Nayak, K.V.S.Rao, D.M.Salunke 2371 11859128 J.Immunol. Epitope Recognition by Diverse Antibodies Suggests Conformational Convergence in an Antibody Response 168 2002
1NTL M.Aslam, J.M.Guthridge, B.K.Hack, R.J.Quigg, V.M.Holers, S.J.Perkins 525 12767833 J.Mol.Biol. The Extended Multidomain Solution Structures of the Complement Protein Crry and its Chimaeric Conjugate Crry-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy 329 2003
1LIL D.B.Huang, C.Ainsworth, A.Solomon, M.Schiffer 1058 n/a Acta Crystallogr D Biol Crystallogr Pitfalls of molecular replacement: The structure determination of an immunoglobulin light-chain dimer. 52 1996
1TET M.Shoham 1169 7690406 J Mol Biol Crystal structure of an anticholera toxin peptide complex at 2.3 A. 232 1993
1CQK M.J.W.Thies, J.Mayer, J.Augustine, C.Frederick, H.Lilie, J.Buchner n/a n/a To be Published Structure of the Ch3 Domain from the Mak33 Antibody n/a n/a
1NFD J.Wang, K.Lim, A.Smolyar, M.Teng, J.Liu, A.G.Tse, J.Liu, R.E.Hussey, Y.Chishti, C.T.Thomson, R.M.Sweet, S.G.Nathenson, H.C.Chang, J.C.Sacchettini, E.L.Reinherz 10 9427737 EMBO J Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. 17 1998
1IGA M.K.Boehm, J.M.Woof, M.A.Kerr, S.J.Perkins 1421 10064707 J Mol Biol The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling. 286 1999
1RZF C.C.Huang, M.Venturi, S.Majeed, M.J.Moore, S.Phogat, M.-Y.Zhang, D.S.Dimitrov, W.A.Hendrickson, J.Robinson, J.Sodroski, R.Wyatt, H.Choe, M.Farzan, P.D.Kwong 2706 14981267 Proc.Nat.Acad.Sci.USA Structural Basis of Tyrosine Sulfation and Vh-Gene Usage in Antibodies that Recognize the HIV Type 1 Coreceptor-Binding Site on Gp120 101 2004
1IGC J.P.Derrick, D.B.Wigley 906 7966308 J Mol Biol The third IgG-binding domain from streptococcal protein G. An analysis by X-ray crystallography of the structure alone and in a complex with Fab. 243 1994
1BLN S.Vasudevan, K.Johns, T.Tsuruo, D.R.Rose 147 n/a PROTEIN AND PEPTIDE LETTERS Preliminary crystallographic analysis of anti P-glycoprotein specific Fab MRK-16 in complex with its antigenic. 3 1996
1YEG B.Gigant, J.B.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 7857 9223277 Proc Natl Acad Sci U S A X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. 94 1997
1YEH B.Gigant, J.B.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 7857 9223277 Proc Natl Acad Sci U S A X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. 94 1997
1YEC J.B.Charbonnier, B.Golinelli-Pimpaneau, B.Gigant, D.S.Tawfik, R.Chap, D.G.Schindler, S.H.Kim, B.S.Green, Z.Eshhar, M.Knossow 1140 9027317 Science Structural convergence in the active sites of a family of catalytic antibodies. 275 1997
1YEF B.Gigant, J.B.Charbonnier, Z.Eshhar, B.S.Green, M.Knossow 7857 9223277 Proc Natl Acad Sci U S A X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. 94 1997
1L0Y H.Li, E.J.Sundberg, R.A.Mariuzza n/a n/a To be Published Crystal Structure of Two Superantigens from Streptococcus Pyogenes Complexed with Their Respective T Cell Receptor Ligands Reveal Novel Superantigen-T Cell Receptor Binding Modes and a Unique T Cell Signaling Complex n/a n/a
1L0X H.Li, E.J.Sundberg, R.A.Mariuzza n/a n/a To be Published Crystal Structure of Two Superantigen from Streptococcus Pyogenes Complexed with Their Respective T Cell Receptor Ligands Reveal Novel Superantigen-T Cell Receptor Binding Modes and a Unique T Cell Signaling Complex n/a n/a
1JCK B.A.Fields, E.L.Malchiodi, H.Li, X.Ysern, C.V.Stauffacher, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 188 8906797 Nature Crystal structure of a T-cell receptor beta-chain complexed with a superantigen. 384 1996
1SBB H.Li, A.Llera, D.Tsuchiya, L.Leder, X.Ysern, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 807 9881971 Immunity Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B. 9 1998
1BEC G.A.Bentley, G.Boulot, K.Karjalainen, R.A.Mariuzza 1984 7701320 Science Crystal structure of the beta chain of a T cell antigen receptor. 267 1995
2GFB B.Golinelli-Pimpaneau, B.Gigant, T.Bizebard, J.Navaza, P.Saludjian, R.Zemel, D.S.Tawfik, Z.Eshhar, B.S.Green, M.Knossow 175 8069632 Structure Crystal structure of a catalytic antibody Fab with esterase-like activity. 2 1994
1EGJ J.Rossjohn, W.J.Mckinstry, J.M.Woodcock, B.J.Mcclure, T.R.Hercus, M.W.Parker, A.F.Lopez, C.J.Bagley 2491 10753826 Blood Structure of the Activation Domain of the Gm-Csf/Il-3/Il-5 Receptor Common Beta-Chain Bound to an Antagonist 95 2000
1TCR K.C.Garcia, M.Degano, R.L.Stanfield, A.Brunmark, M.R.Jackson, P.A.Peterson, L.Teyton, I.A.Wilson 209 8824178 Science An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. 274 1996
1KGC L.Kjer-Nielsen, C.S.Clements, A.G.Brooks, A.W.Purcell, J.Mccluskey, J.Rossjohn 1521 12429093 Structure The 1.5 A Crystal Structure of a Highly Selected Antiviral T Cell Receptor Provides Evidence for a Structural Basis of Immunodominance 10 2002
1KTK E.J.Sundberg, H.Li, A.S.Llera, J.K.Mccormick, J.Tormo, P.M.Schlievert, K.Karjalainen, R.A.Mariuzza 687 12015151 Structure Structures of Two Streptococcal Superantigens Bound to Tcr Beta Chains Reveal Diversity in the Architecture of T Cell Signaling Complexes 10 2002

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