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Phenylalanine Hydroxylase

PDB ID	Authors	First Page	PubMed ID	Journal Name	Citation Title	Volume No	Publication Year
1DMW	H.Erlandsen, E.Bjorgo, T.Flatmark, R.C.Stevens	2208	10694386	Biochemistry	Crystal Structure and Site-Specific Mutagenesis of Pterin-Bound Human Phenylalanine Hydroxylase	39	2000
1I4S	J.Blaszczyk, J.E.Tropea, M.Bubunenko, K.M.Routzahn, D.S.Waugh, D.L.Court, X.Ji	1225	11738048	Structure	Crystallographic and Modeling Studies of Rnase III Suggest a Mechanism for Double-Stranded RNA Cleavage	9	2001
1J8T	O.A.Andersen, T.Flatmark, E.Hough	266	11718561	J.Mol.Biol.	High Resolution Crystal Structures of the Catalytic Domain of Human Phenylalanine Hydroxylase in its Catalytically Active Fe(II) Form and Binary Complex with Tetrahydrobiopterin	314	2001
1J8U	O.A.Andersen, T.Flatmark, E.Hough	266	11718561	J.Mol.Biol.	High Resolution Crystal Structures of the Catalytic Domain of Human Phenylalanine Hydroxylase in its Catalytically Active Fe(II) Form and Binary Complex with Tetrahydrobiopterin	314	2001
1JFZ	J.Blaszczyk, J.E.Tropea, M.Bubunenko, K.M.Routzahn, D.S.Waugh, D.L.Court, X.Ji	1225	11738048	Structure	Crystallographic and Modeling Studies of Rnase III Suggest a Mechanism for Double-Stranded RNA Cleavage.	9	2001
1KW0	O.A.Andersen, T.Flatmark, E.Hough	1095	12126628	J.Mol.Biol.	Crystal Structure of the Ternary Complex of the Catalytic Domain of Human Phenylalanine Hydroxylase with Tetrahydrobiopterin and 3-(2-Thienyl)-L-Alanine, and its Implications for the Mechanism of Catalysis and Substrate Activation	320	2002
1LRM	n/a	n/a	n/a	Unpublished	n/a	n/a	n/a
1LTU	H.Erlandsen, J.Y.Kim, M.G.Patch, A.Han, A.Volner, M.M.Abu-Omar, R.C.Stevens	645	12096915	J.Mol.Biol.	Structural Comparison of Bacterial and Human Iron-Dependent Phenylalanine Hydroxylases: Similar Fold, Different Stability and Reaction Rates	320	2002
1LTV	H.Erlandsen, J.Y.Kim, M.G.Patch, A.Han, A.Volner, M.M.Abu-Omar, R.C.Stevens	645	12096915	J.Mol.Biol.	Structural Comparison of Bacterial and Human Iron-Dependent Phenylalanine Hydroxylases: Similar Fold, Different Stability and Reaction Rates	320	2002
1LTZ	H.Erlandsen, J.Y.Kim, M.G.Patch, A.Han, A.Volner, M.M.Abu-Omar, R.C.Stevens	645	12096915	J.Mol.Biol.	Structural Comparison of Bacterial and Human Iron-Dependent Phenylalanine Hydroxylases: Similar Fold, Different Stability and Reaction Rates	320	2002
1MDO	B.W.Noland, J.M.Newman, J.Hendle, J.Badger, J.A.Christopher, J.Tresser, M.D.Buchanan, T.Wright, M.E.Rutter, W.E.Sanderson, H.-J.Muller-Dieckmann, K.Gajiwala, S.G.Buchanan	1569	12429098	Structure	Structural Studies of Salmonella Typhimurium Arnb (Pmrh) Aminotransferase:A 4-Amino-4-Deoxy-L-Arabinose Liposaccharide Modifying Enzyme	10	2002
1MDX	B.W.Noland, J.M.Newman, J.Hendle, J.Badger, J.A.Christopher, J.Tresser, M.D.Buchanan, T.A.Wright, M.E.Rutter, W.E.Sanderson, H.-J.Muller-Dieckmann, K.S.Gajiwala, S.G.Buchanan	1569	12429098	Structure	Structural Studies of Salmonella Typhimurium Arnb (Pmrh) Aminotransferase:A 4-Amino-4-Deoxy-L-Arabinose Liposaccharide Modifying Enzyme	10	2002
1MDZ	B.W.Noland, J.M.Newman, J.Hendle, J.Badger, J.A.Christopher, J.Tresser, M.D.Buchanan, T.Wright, M.E.Rutter, W.E.Sanderson, H.-J.Muller-Dieckmann, K.S.Gajiwala, S.G.Buchanan	1569	12429098	Structure	Structural Studies of Salmonella Typhimurium Arnb (Pmrh) Aminotransferase:A 4-Amino-4-Deoxy-L-Arabinose Liposaccharide Modifying Enzyme	10	2002
1MLW	L.Wang, H.Erlandsen, J.Haavik, P.M.Knappskog, R.C.Stevens	12569	12379098	Biochemistry	Three-Dimensional Structure of Human Tryptophan Hydroxylase and its Implications for the Biosynthesis of the Neurotransmitters Serotonin and Melatonin	41	2002
1MMK	O.A.Andersen, T.Flatmark, E.Hough	n/a	n/a	To be Published	2.0 A Resolution Crystal Crystal Structures of the Catalytic Domain of Human Phenylalanine Hydroxylase Complexed with Tetrahydrobiopterin Plus 3-(2-Thienyl)-L-Alanine and Tetrahydrobiopterin Plus L-2-Aminohexanoic Acid	n/a	n/a
1MMT	O.A.Andersen, T.Flatmark, E.Hough	n/a	n/a	To be Published	2.0 A Resolution Crystal Crystal Structures of the Catalytic Domain of Human Phenylalanine Hydroxylase Complexed with Tetrahydrobiopterin Plus 3-(2-Thienyl)-L-Alanine and Tetrahydrobiopterin Plus L-2-Aminohexanoic Acid	n/a	n/a
1PAH	H.Erlandsen, F.Fusetti, A.Martinez, E.Hough, T.Flatmark, R.C.Stevens	995	9406548	Nat Struct Biol	Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.	4	1997
1PHZ	B.Kobe, I.G.Jennings, C.M.House, B.J.Michell, K.E.Goodwill, B.D.Santarsiero, R.C.Stevens, R.G.Cotton, B.E.Kemp	442	10331871	Nat Struct Biol	Structural basis of autoregulation of phenylalanine hydroxylase.	6	1999
1R8K	J.Osipiuk, P.Quartey, S.Moy, F.Collart, A.Joachimiak	n/a	n/a	To be Published	Crystal Structure of Nad-Dependent Dehydrogenase/Carboxylase of Salmonella Typhimurium	n/a	n/a
1RC5	J.Blaszczyk, J.Gan, J.E.Tropea, D.L.Court, D.S.Waugh, X.Ji	457	15016361	Structure	Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.	12	2004
1RC7	J.Blaszczyk, J.Gan, J.E.Tropea, D.L.Court, D.S.Waugh, X.Ji	457	15016361	Structure	Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.	12	2004
1TDW	H.Erlandsen, A.L.Pey, A.Gamez, B.Perez, L.R.Desviat, C.Aguado, R.Koch, S.Surendran, S.Tyring, R.Matalon, C.R.Scriver, M.Ugarte, A.Martinez, R.C.Stevens	16903	n/a	Proc.Natl.Acad.Sci.USA	Correction of Kinetic and Stability Defects by Tetrahydrobiopterin in Phenylketonuria Patients with Certain Phenylalanine Hydroxylase Mutations	101	2004
1TG2	H.Erlandsen, A.L.Pey, A.Gamez, B.Perez, L.R.Desviat, C.Aguado, R.Koch, S.Surendran, S.Tyring, R.Matalon, C.R.Scriver, M.Ugarte, A.Martinez, R.C.Stevens	16903	n/a	Proc.Natl.Acad.Sci.USA	Correction of Kinetic and Stability Defects by Tetrahydrobiopterin in Phenylketonuria Patients with Certain Phenylalanine Hydroxylase Mutations	101	2004
1TOH	K.E.Goodwill, C.Sabatier, C.Marks, R.Raag, P.F.Fitzpatrick, R.C.Stevens	578	9228951	Nat Struct Biol	Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases.	4	1997
2PAH	F.Fusetti, H.Erlandsen, T.Flatmark, R.C.Stevens	16962	9642259	J.Biol.Chem.	Structure of Tetrameric Human Phenylalanine Hydroxylase and its Implications for Phenylketonuria	273	1998
2PHM	B.Kobe, I.G.Jennings, C.M.House, B.J.Michell, K.E.Goodwill, B.D.Santarsiero, R.C.Stevens, R.G.Cotton, B.E.Kemp	442	10331871	Nat Struct Biol	Structural basis of autoregulation of phenylalanine hydroxylase.	6	1999
2TOH	K.E.Goodwill, C.Sabatier, R.C.Stevens	13437	9753429	Biochemistry	Crystal Structure of Tyrosine Hydroxylase with Bound Cofactor Analogue and Iron at 2.3 A Resolution: Self-Hydroxylation of Phe300 and the Pterin-Binding Site	37	1998
3PAH	H.Erlandsen, T.Flatmark, R.C.Stevens, E.Hough	15638	9843368	Biochemistry	Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.	37	1998
4PAH	H.Erlandsen, T.Flatmark, R.C.Stevens, E.Hough	15638	9843368	Biochemistry	Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.	37	1998
5PAH	H.Erlandsen, T.Flatmark, R.C.Stevens, E.Hough	15638	9843368	Biochemistry	Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.	37	1998
6PAH	H.Erlandsen, T.Flatmark, R.C.Stevens, E.Hough	15638	9843368	Biochemistry	Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.	37	1998