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RNA-Polymerase
Exploring the Structure
PDB entry 1msw contains a remarkable structure showing RNA polymerase in action. The structure includes a very small RNA polymerase that is made by the bacteriophage T7, shown here with blue tubes. A small transcription bubble, composed of two DNA strands and an RNA strand, is bound in the active site. Notice how the two DNA strands form a double helix at the top of the picture. The enzyme separates them in the middle and builds an RNA strand using the DNA on the right. Finally, at the bottom, the two DNA strands come back together.This illustration was created with RasMol. You can create similar images by clicking on the accession code above and choosing one of the options under View Structure.
A list of all RNA polymerase structures in the PDB as of April, 2003, is available here. For more information on RNA polymerase, click here.
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Last changed by: A.Honegger,