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Glycogen Phosphorylase
| PDB ID | Authors | First Page | Journal Name | Title | Volume No | Publication Year |
| 1A8I | M.Gregoriou, M.E.Noble, K.A.Watson, E.F.Garman, T.M.Krulle, C.de la Fuente, G.W.Fleet, N.G.Oikonomakos, L.N.Johnson | 915 | Protein Sci | The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding. | 7 | 1998 |
| 1ABB | D.D.Leonidas, N.G.Oikonomakos, A.C.Papageorgiou, K.R.Acharya, D.Barford, L.N.Johnson | 1112 | Protein Sci | Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate. | 1 | 1992 |
| 1AXR | T.D.Heightman, A.Vasella, K.E.Tsitsanou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos | 853 | HELVETICA CHIMICA ACTA | Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase b. | 81 | 1998 |
| 1B4D | K.E.Tsitsanou, N.G.Oikonomakos, S.E.Zographos, V.T.Skamnaki, M.Gregoriou, K.A.Watson, L.N.Johnson, G.W.J.Fleet | 741 | Protein Sci. | Effects of Commonly Used Cryoprotectants on Glycogen Phosphorylase Activity and Structure | 8 | 1999 |
| 1BX3 | K.E.Tsitsanou, N.G.Oikonomakos, S.E.Zographos, V.T.Skamnaki, M.Gregoriou, K.A.Watson, L.N.Johnson, G.W.J.Fleet | 741 | Protein Sci. | Effects of Commonly Used Cryoprotectants on Glycogen Phosphorylase Activity and Structure | 8 | 1999 |
| 1C50 | N.G.Oikonomakos, V.T.Skamnaki, K.E.Tsitsanou, N.G.Gavalas, L.N.Johnson | 575 | Structure (London) | A New Allosteric Site in Glycogen Phosphorylase B as a Target for Drug Interactions | 8 | 2000 |
| 1C8K | N.G.Oikonomakos, J.B.Schnier, S.E.Zographos, V.T.Skamnaki, K.E.Tsitsanou, L.N.Johnson | 34566 | J.Biol.Chem. | Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site | 275 | 2000 |
| 1C8L | K.E.Tsitsanou, V.T.Skamnaki, N.G.Oikonomakos | n/a | To be Published | Synergistic Inhibition of Glycogen Phosphorylase a by a Potential Antidiabetic Drug and Caffeine: Kinetic and Crystallographic Studies | n/a | n/a |
| 1E1Y | N.G.Oikonomakos, J.B.Schnier, S.E.Zographos, V.T.Skamnaki, K.E.Tsitsanou, L.N.Johnson | 34566 | J.Biol.Chem. | Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site | 275 | 2000 |
| 1EM6 | V.L.Rath, M.Ammirati, D.E.Danley, J.L.Ekstrom, E.M.Gibbs, T.R.Hynes, A.M.Mathiowetz, R.K.McPherson, T.V.Olson, J.L Treadway, D.J.Hoover | 677 | Chem.Biol. | Human Liver Glycogen Phosphorylase Inhibitors Bind at a New Allosteric Site | 7 | 2000 |
| 1EXV | V.L.Rath, M.Ammirati, D.E.Danley, J.L.Ekstrom, E.M.Gibbs, T.R.Hynes, A.M.Mathiowetz, R.K.McPherson, T.V.Olson, J.L Treadway, D.J.Hoover | 677 | Chem.Biol. | Human Liver Glycogen Phosphorylase Inhibitors Bind at a New Allosteric Site | 7 | 2000 |
| 1FA9 | V.L.Rath, M.Ammirati, P.K.Lemotte, K.F.Fennell, M.N.Mansour, D.E.Danley, T.R.Hynes, G.K.Schulte, D.J.Wasilko, J.Pandit | 139 | Mol. Cell | Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core | 6 | 2000 |
| 1FC0 | V.L.Rath, M.Ammirati, P.K.Lemotte, K.F.Fennell, M.M.Mansour, D.E.Danley, T.R.Hynes, G.K.Schulte, D.J.Wasilko, J.Pandit | 139 | Mol. Cell | Activation of Human Liver Glycogen Phosphorylase by Altering the Secondary Structure and Packing of the Catalytic Core | 6 | n/a |
| 1FS4 | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FTQ | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FTW | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FTY | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FU4 | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FU7 | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1FU8 | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1GFZ | N.G.Oikonomakos, S.E.Zographos, V.T.Skamnaki, K.E.Tsitsanou, L.N.Johnson | n/a | To be Published | Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site | n/a | n/a |
| 1GG8 | K.A.Watson, E.P.Mitchell, L.N.Johnson, J.C.Son, C.J.Bichard, M.G.Orchard, G.W.Fleet, N.G.Oikonomakos, D.D.Leonidas, M.Kontou, A.C.Papageorgiou | 5745 | Biochemistry | Design of Inhibitors of Glycogen Phosphorylase: A Study of Alpha-and Beta-C-Glucosides and 1-Thio-Beta-D-Glucose Compounds. | 33 | 1994 |
| 1GGN | K.A.Watson, K.E.Tsitsanou, M.Gregoriou, S.E.Zographos, V.T.Skamnaki, N.G.Oikonomakos, G.W.Fleet, L.N.Johnson | n/a | To be Published | Structures of Glycogen Phosphorylase-Inhibitor Complexes and the Implications for Structure-Based Drug Design | n/a | n/a |
| 1GPA | D.Barford, S.H.Hu, L.N.Johnson | 233 | J Mol Biol | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. | 218 | 1991 |
| 1GPB | K.R.Acharya, D.I.Stuart, K.M.Varvill, L.N.Johnson | 1 | Glycogen Phosphorylase B: Description of the Protein Structure | Glycogen Phosphorylase B: Description of the Protein Structure | n/a | 1991 |
| 1GPY | L.N.Johnson, P.Snape, J.L.Martin, K.R.Acharya, D.Barford, N.G.Oikonomakos | 253 | J Mol Biol | Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b. | 232 | 1993 |
| 1H5U | N.G.Oikonomakos, S.E.Zographos, V.T.Skamnaki, G.Archontis | n/a | To be Published | The 1.76 A Resolution Crystal Structure of Glycogen Phosphorylase B Complexed with Glucose and Cp320626, a Potential Antidiabetic Drug | n/a | n/a |
| 1HLF | N.G.Oikonomakos, V.T.Skamnaki, T.Dosca, B.Toth, P.Gergely, E.Osz, L.Szilagyi, L.Somsak | n/a | To be Published | Binding of Glucopyranosylidene-Spiro-Thiohydantoin to Glycogen Phosphorylase B: Kinetic and Crystallographic Studies | n/a | n/a |
| 1K06 | N.G.Oikonomakos, M.Kosmopoulou, S.E.Zographos, D.D.Leonidas, L.Somsak, V.Nagy, J.P.Praly, T.Dosca, B.Toth, P.Gergely | n/a | To be Published | The Binding of N-Acetyl-and N-Benzoyl-N'-Beta-D-Glucopyranosyl Ureas to Glycogen Phosphorylase B: Kinetic and Crystallographic Studies | n/a | n/a |
| 1K08 | N.G.Oikonomakos, M.Kosmopoulou, S.E.Zographos, D.D.Leonidas, L.Somsak, V.Nagy, J.P.Praly, T.Dosca, B.Toth, P.Gergely | n/a | To be Published | The Binding of N-Acetyl-and N-Benzoyl-N'-Beta-D-Glucopyranosyl Ureas to Glycogen Phosphorylase B: Kinetic and Crystallographic Studies | n/a | n/a |
| 1K0Q | N.G.Oikonomakos, M.Kosmopoulou, S.E.Zographos, D.D.Leonidas, L.Somsak, V.Nagy, J.P.Praly, T.Dosca, B.Toth, P.Gergely | n/a | To be Published | The Binding of N-Acetyl-and N-Benzoyl-N'-Beta-D-Glucopyranosyl Ureas to Glycogen Phosphorylase B: Kinetic and Crystallographic Studies | n/a | n/a |
| 1NOI | E.P.Mitchell, S.G.Withers, P.Ermert, A.T.Vasella, E.F.Garman, N.G.Oikonomakos, L.N.Johnson | 7341 | Biochemistry | Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. | 35 | 1996 |
| 1NOJ | E.P.Mitchell, S.G.Withers, P.Ermert, A.T.Vasella, E.F.Garman, N.G.Oikonomakos, L.N.Johnson | 7341 | Biochemistry | Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. | 35 | 1996 |
| 1NOK | E.P.Mitchell, S.G.Withers, P.Ermert, A.T.Vasella, E.F.Garman, N.G.Oikonomakos, L.N.Johnson | 7341 | Biochemistry | Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. | 35 | 1996 |
| 1PYG | S.R.Sprang, S.G.Withers, E.J.Goldsmith, R.J.Fletterick, N.B.Madsen | 1367 | Science | Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate. | 254 | 1991 |
| 1YGP | K.Lin, V.L.Rath, S.C.Dai, R.J.Fletterick, P.K.Hwang | 1539 | Science | A protein phosphorylation switch at the conserved allosteric site in GP. | 273 | 1996 |
| 2AMV | S.E.Zographos, N.G.Oikonomakos, K.E.Tsitsanou, D.D.Leonidas, E.D.Chrysina, V.T.Skamnaki, H.Bischoff, S.Goldmann, K.A.Watson, L.N.Johnson | 1413 | Structure | The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. | 5 | 1997 |
| 2ECP | M.O'Reilly, K.A.Watson, L.N.Johnson | 5337 | Biochemistry | The Crystal Structure of the Escherichia Coli Maltodextrin Phosphorylase- Acarbose Complex | 38 | 1999 |
| 2GPA | N.G.Oikonomakos, K.E.Tsitsanou, S.E.Zographos, V.T.Skamnaki, S.Goldmann, H.Bischoff | 1930 | Protein Sci. | Allosteric Inhibition of Glycogen Phosphorylase a by the Potential Antidiabetic Drug 3-Isopropyl 4-(2-Chlorophenyl)-1,4-Dihydro-1-Ethyl-2-Methyl- Pyridin-3,5,6-Tricarboxylate | 8 | 1999 |
| 2GPB | J.L.Martin, L.N.Johnson, S.G.Withers | 10745 | Biochemistry | Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. | 29 | 1990 |
| 2GPN | M.Gregoriou, M.E.Noble, K.A.Watson, E.F.Garman, T.M.Krulle, C.de la Fuente, G.W.Fleet, N.G.Oikonomakos, L.N.Johnson | 915 | Protein Sci | The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding. | 7 | 1998 |
| 2PRI | N.G.Oikonomakos, S.E.Zographos, L.N.Johnson, A.C.Papageorgiou, K.R.Acharya | 900 | J.Mol.Biol. | The Binding of 2-Deoxy-Glucose-6-Phosphate to Glycogen Phosphorylase B: Kinetic and Crystallographic Studies | 254 | 1995 |
| 2PRJ | N.G.Oikonomakos, M.Kontou, S.E.Zographos, K.A.Watson, L.N.Johnson, C.J.Bichard, G.W.Fleet, K.R.Acharya | 2469 | Protein Sci | N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose. | 4 | 1995 |
| 2SKC | N.G.Oikonomakos, S.E.Zographos, K.E.Tsitsanou, L.N.Johnson, K.R.Acharya | 2416 | Protein Sci | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. | 5 | 1996 |
| 2SKD | N.G.Oikonomakos, S.E.Zographos, K.E.Tsitsanou, L.N.Johnson, K.R.Acharya | 2416 | Protein Sci | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. | 5 | 1996 |
| 2SKE | N.G.Oikonomakos, S.E.Zographos, K.E.Tsitsanou, L.N.Johnson, K.R.Acharya | 2416 | Protein Sci | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. | 5 | 1996 |
| 3AMV | N.G.Oikonomakos, K.E.Tsitsanou, S.E.Zographos, V.T.Skamnaki, S.Goldmann, H.Bischoff | 1930 | Protein Sci. | Allosteric Inhibition of Glycogen Phosphorylase a by the Potential Antidiabetic Drug 3-Isopropyl 4-(2-Chlorophenyl)-1,4-Dihydro-1-Ethyl-2-Methyl- Pyridine-3,5,6-Tricarboxylate. | 8 | 1999 |
| 3GPB | J.L.Martin, L.N.Johnson, S.G.Withers | 10745 | Biochemistry | Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. | 29 | 1990 |
| 4GPB | J.L.Martin, L.N.Johnson, S.G.Withers | 10745 | Biochemistry | Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. | 29 | 1990 |
| 5GPB | J.L.Martin, L.N.Johnson, S.G.Withers | 10745 | Biochemistry | Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. | 29 | 1990 |
| 6GPB | L.N.Johnson, K.R.Acharya, M.D.Jordan, P.J.McLaughlin | 645 | J Mol Biol | Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex. | 211 | 1990 |
| 7GPB | D.Barford, S.H.Hu, L.N.Johnson | 233 | J Mol Biol | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. | 218 | 1991 |
| 8GPB | D.Barford, S.H.Hu, L.N.Johnson | 233 | J Mol Biol | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. | 218 | 1991 |
| 9GPB | D.Barford, L.N.Johnson | 609 | Nature | The allosteric transition of glycogen phosphorylase. | 340 | 1989 |
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