Inhaltsübersicht | Nanomaschinen | Moleküle | Programme | Kurse | Fun | Links

>

Antibodies

Attack From Many Angles

When a foreign molecule is found in the blood, many different antibodies may bind to it, attacking at different angles. Three different antibodies that bind to the protein lysozyme (in green at the center) are shown here. The crystal structures (PDB entries 1fdl, 3hfl, and 3hfm) each include only one arm of the antibody (termed "Fab" for "antigen-binding fragment"), which has been separated from the antibody for ease in study. The rest of the antibody is indicated extending from the edges of the illustration. Notice that the antibodies pick entirely different binding sites on the small lysozyme molecule.

Next: Catalytic Antibodies
Previous: Antibodies

PDB Molecule of the Month September 2001, by David S. Goodsell

Last changed by: A.Honegger, 8/4/06