Welcome to the Laboratory of Prof. Dr. Andreas Plückthun.
We study the creation of new proteins and protein variants.
Our Main Research Topics
We study the creation of new proteins and protein variants. The purpose of this work is to use such engineered proteins in biomedical research and novel applications, including therapy.
Gene therapy using shielded, retargeted adenovirus
Structure and mechanism of G-protein coupled receptors
Designed Armadillo Repeat Proteins for creating modular, sequence-specific binding to linear epitopes
Our technology components
Many of the studies in the various projects required technologies that were simply not available at the time. Therefore, we have always been developing novel technologies to be able to greatly expand our toolbox, in order to make several developments in molecular engineering possible in the first place.
Designed Ankyrin Repeat Proteins as Scaffolds for Selective Binding
Antibody Engineering
Directed Evolution: Ribosome Display, Yeast Display, Phage Display
Directed Evolution and Engineering for Stability of GPCRs
Structural Biology
