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Multidrug Resistance Transporters

A list of 'multidrug transporter' related entries in the PDB

as determined by a keyword search on October 30, 2007

Structure ID  Title Authors Publication Year Journal Name Volume ID First Page Pubmed
1BOW Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Zheleznova, E.E., Markham, P.N., Neyfakh, A.A., Brennan, R.G. 1999 Cell 96 353 10025401
1EXI Crystal structure of the transcription activator BmrR bound to DNA and a drug. Heldwein, E.E., Brennan, R.G. 2001 Nature 409 378 11201751
1EXJ Crystal structure of the transcription activator BmrR bound to DNA and a drug. Heldwein, E.E., Brennan, R.G. 2001 Nature 409 378 11201751
1IWG Crystal structure of bacterial multidrug efflux transporter AcrB Murakami, S., Nakashima, R., Yamashita, E., Yamaguchi, A. 2002 NATURE 419 587 12374972
1JBG Crystal structure of MtaN, a global multidrug transporter gene activator. Godsey, M.H., Baranova, N.N., Neyfakh, A.A., Brennan, R.G. 2001 J.Biol.Chem. 276 47178 11581256
1MV5 Crystal structure of LmrA ATP-binding domain reveals the two-site alternating mechanism at molecular level Yuan, Y., Chen, H., Patel, D. n/a To be Published n/a n/a n/a
1NY9 Structural basis for antibiotic recognition by the TipA-class of multidrug-resistance transcriptional regulators Kahmann, J.D., Sass, H.J., Allan, M.G., Seto, H., Thompson, C.J., Grzesiek, S. 2003 Embo J. 22 1824 12682015
1R8D The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. Newberry, K.J., Brennan, R.G. 2004 J.Biol.Chem. 279 20356 14985361
1R8E The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. Newberry, K.J., Brennan, R.G. 2004 J.Biol.Chem. 279 20356 14985361
1VF7 Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa Akama, H., Matsuura, T., Kashiwagi, S., Yoneyama, H., Narita, S., Tsukihara, T., Nakagawa, A., Nakae, T. 2004 J.Biol.Chem. 279 25939 15117957
2BOW Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Zheleznova, E.E., Markham, P.N., Neyfakh, A.A., Brennan, R.G. 1999 Cell 96 353 10025401
2DHH Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T., Yamaguchi, A. 2006 Nature 443 173 16915237
2DR6 Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T., Yamaguchi, A. 2006 Nature 443 173 16915237
2DRD Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Murakami, S., Nakashima, R., Yamashita, E., Matsumoto, T., Yamaguchi, A. 2006 Nature 443 173 16915237
2GFP Structure of the multidrug transporter EmrD from Escherichia coli Yin, Y., He, X., Szewczyk, P., Nguyen, T., Chang, G. 2006 Science 312 741 16675700
2GIF Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M. 2006 Science 313 1295 16946072
2HQC Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W. 2006 J.Bacteriol. 188 7290 17015668
2HQD Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W. 2006 J.Bacteriol. 188 7290 17015668
2HQF Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W. 2006 J.Bacteriol. 188 7290 17015668
2HQG Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway Su, C.-C., Li, M., Gu, R., Takatsuka, Y., McDermott, G., Nikaido, H., Yu, E.W. 2006 J.Bacteriol. 188 7290 17015668
2HYD Structure of a bacterial multidrug ABC transporter. Dawson, R.J., Locher, K.P. 2006 Nature 443 180 16943773
2I68 Quasi-symmetry in the Cryo-EM Structure of EmrE Provides the Key to Modeling its Transmembrane Domain Fleishman, S.J., Harrington, S.E., Enosh, A., Halperin, D., Tate, C.G., Ben-Tal, N. 2006 J.Mol.Biol. 364 54 17005200
2I6W Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids. Das, D., Xu, Q.S., Lee, J.Y., Ankoudinova, I., Huang, C., Lou, Y., Degiovanni, A., Kim, R., Kim, S.H. 2007 J.Struct.Biol. 158 494 17275331
2ONJ Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP. Dawson, R.J.P., Locher, K.P. 2007 Febs Lett. 581 935 17303126

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Last changed by: A.Honegger, 8/6/08