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Trypsin
PDB ID Authors First Page Medline Link Journal Name Title Volume No Publication Year
1A0J H.K.Schroder, N.P.Willassen, A.O.Smalas 780 9757092 Acta Crystallogr D Biol Crystallogr Structure of a non-psychrophilic trypsin from a cold-adapted fish species. 54 1998
1A0L P.J.Pereira, A.Bergner, S.Macedo-Ribeiro, R.Huber, G.Matschiner, H.Fritz, C.P.Sommerhoff, W.Bode 306 9521329 Nature Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. 392 1998
1A1Q R.A.Love, H.E.Parge, J.A.Wickersham, Z.Hostomsky, N.Habuka, E.W.Moomaw, T.Adachi, Z.Hostomska 331 8861916 Cell The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. 87 1996
1A2C J.L.R.Steiner, M.Murakami, A.Tulinsky 597 ( 1A2C ) J Am Chem Soc Structure of thrombin inhibited by aeruginosin 298-A from a blue-green alga. 120 1998
1A5H M.Renatus, W.Bode, R.Huber, J.Sturzebecher, D.Prasa, S.Fischer, U.Kohnert, M.T.Stubbs 21713 9268299 J Biol Chem Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors. 272 1997
1A5I M.Renatus, M.T.Stubbs, R.Huber, P.Bringmann, P.Donner, W.D.Schleuning, W.Bode 13483 9354616 Biochemistry Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage. 36 1997
1AAL C.Eigenbrot, M.Randal, A.A.Kossiakoff 75 1384034 Proteins Structural effects induced by mutagenesis affected by crystal packing factors: the structure of a 30-51 disulfide mutant of basic pancreatic trypsin inhibitor. 14 1992
1AAP T.R.Hynes, M.Randal, L.A.Kennedy, C.Eigenbrot, A.A.Kossiakoff 10018 2125487 Biochemistry X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor. 29 1990
1AB9 N.H.Yennawar, H.P.Yennawar, G.K.Farber 7326 8003497 Biochemistry X-ray crystal structure of gamma-chymotrypsin in hexane. 33 1994
1ABI X.Qiu, K.P.Padmanabhan, V.E.Carperos, A.Tulinsky, T.Kline, J.M.Maraganore, .2.Fenton 2d 11689 1445905 Biochemistry Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors. 31 1992
1ABJ X.Qiu, K.P.Padmanabhan, V.E.Carperos, A.Tulinsky, T.Kline, J.M.Maraganore, .2.Fenton 2d 11689 1445905 Biochemistry Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors. 31 1992
1ACB F.Frigerio, A.Coda, L.Pugliese, C.Lionetti, E.Menegatti, G.Amiconi, H.P.Schnebli, P.Ascenzi, M.Bolognesi 107 1583684 J Mol Biol Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin c complex at 2.0 A resolution. 225 1992
1ADZ M.J.Burgering, L.P.Orbons, A.van der Doelen, J.Mulders, H.J.Theunissen, P.D.Grootenhuis, W.Bode, R.Huber, M.T.Stubbs 395 9199408 J Mol Biol The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. 269 1997
1AE8 G.De Simone, G.Balliano, P.Milla, C.Gallina, C.Giordano, C.Tarricone, M.Rizzi, M.Bolognesi, P.Ascenzi 558 9217260 J Mol Biol Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. 269 1997
1AFE G.De Simone, G.Balliano, P.Milla, C.Gallina, C.Giordano, C.Tarricone, M.Rizzi, M.Bolognesi, P.Ascenzi 558 9217260 J Mol Biol Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. 269 1997
1AFQ N.H.Yennawar, H.P.Yennawar, G.K.Farber 7326 8003497 Biochemistry X-ray crystal structure of gamma-chymotrypsin in hexane. 33 1994
1AHT Z.Chen, Y.Li, A.M.Mulichak, S.D.Lewis, J.A.Shafer 198 7574675 Arch Biochem Biophys Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution. 322 1995
1AKS A.Johnson, S.Krishnaswamy, P.V.Sundaram, V.Pattabhi 311 ( 1AKS ) Acta Crystallogr D Biol Crystallogr The first structure at 1.8 angstrom resolution of an active autolysate form of porcine alpha-trypsin. 53 1997
1AMB J.Talafous, K.J.Marcinowski, G.Klopman, M.G.Zagorski 7788 7516706 Biochemistry Solution structure of residues 1-28 of the amyloid beta-peptide. 33 1994
1AMC J.Talafous, K.J.Marcinowski, G.Klopman, M.G.Zagorski 7788 7516706 Biochemistry Solution structure of residues 1-28 of the amyloid beta-peptide. 33 1994
1AMH J.J.Perona, C.S.Craik 337 7795518 Protein Sci Structural basis of substrate specificity in the serine proteases. 4 1995
1AN1 S.Di Marco, J.P.Priestle 1465 9384562 Structure Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system. 5 1997
1ANB M.E.McGrath, J.R.Vasquez, C.S.Craik, A.S.Yang, B.Honig, R.J.Fletterick 3059 1554694 Biochemistry Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. 31 1992
1ANC M.E.McGrath, J.R.Vasquez, C.S.Craik, A.S.Yang, B.Honig, R.J.Fletterick 3059 1554694 Biochemistry Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. 31 1992
1AND M.E.McGrath, B.L.Haymore, N.L.Summers, C.S.Craik, R.J.Fletterick 1914 8448149 Biochemistry Structure of an engineered, metal-actuated switch in trypsin. 32 1993
1ANE n/a n/a ( 1ANE ) n/a n/a n/a n/a
1AO5 D.E.Timm 1418 9232643 Protein Sci The crystal structure of the mouse glandular kallikrein-13 (prorenin converting enzyme). 6 1997
1AQ7 B.Sandler, M.Murakami, J.Clardy 595 ( 1AQ7 ) J Am Chem Soc Atomic structure of the trypsin-aeruginosin 98-B complex. 120 1998
1AS4 C.M.Lukacs, H.Rubin, D.W.Christianson 3297 9521649 Biochemistry Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. 37 1998
1ATA B.L.Grasberger, G.M.Clore, A.M.Gronenborn 669 7922043 Structure High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site. 2 1994
1ATB B.L.Grasberger, G.M.Clore, A.M.Gronenborn 669 7922043 Structure High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site. 2 1994
1ATD B.L.Grasberger, G.M.Clore, A.M.Gronenborn 669 7922043 Structure High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site. 2 1994
1ATE B.L.Grasberger, G.M.Clore, A.M.Gronenborn 669 7922043 Structure High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site. 2 1994
1ATT L.Mourey, J.P.Samama, M.Delarue, M.Petitou, J.Choay, D.Moras 223 8331659 J Mol Biol Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution. 232 1993
1ATU S.E.Ryu, H.J.Choi, K.S.Kwon, K.N.Lee, M.H.Yu 1181 8939743 Structure The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A. 4 1996
1AUJ S.L.Lee, R.S.Alexander, A.Smallwood, R.Trievel, L.Mersinger, P.C.Weber, C.Kettner 13180 9341205 Biochemistry New inhibitors of thrombin and other trypsin-like proteases: hydrogen bonding of an aromatic cyano group with a backbone amide of the P1 binding site replaces binding of a basic side chain. 36 1997
1AUT T.Mather, V.Oganessyan, P.Hof, R.Huber, S.Foundling, C.Esmon, W.Bode 6822 9003757 EMBO J The 2.8 A crystal structure of Gla-domainless activated protein C. 15 1996
1AV7 V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
1AVT V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
1AVU H.K.Song, S.W.Suh 347 9466914 J Mol Biol Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. 275 1998
1AVW H.K.Song, S.W.Suh 347 9466914 J Mol Biol Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. 275 1998
1AVX H.K.Song, S.W.Suh 347 9466914 J Mol Biol Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. 275 1998
1AWF M.P.Weir, S.S.Bethell, A.Cleasby, C.J.Campbell, R.J.Dennis, C.J.Dix, H.Finch, H.Jhoti, C.J.Mooney, S.Patel, C.M.Tang, M.Ward, A.J.Wonacott, C.W.Wharton 6645 9578548 Biochemistry Novel natural product 5,5-trans-lactone inhibitors of human alpha- thrombin: mechanism of action and structural studies. 37 1998
1AWH M.P.Weir, S.S.Bethell, A.Cleasby, C.J.Campbell, R.J.Dennis, C.J.Dix, H.Finch, H.Jhoti, C.J.Mooney, S.Patel, C.M.Tang, M.Ward, A.J.Wonacott, C.W.Wharton 6645 9578548 Biochemistry Novel natural product 5,5-trans-lactone inhibitors of human alpha- thrombin: mechanism of action and structural studies. 37 1998
1AXJ E.Liepinsh, M.Kitamura, T.Murakami, T.Nakaya, G.Otting 975 9406543 Nat Struct Biol Pathway of chymotrypsin evolution suggested by the structure of the FMN-binding protein from Desulfovibrio vulgaris. 4 1997
1AZ8 R.Alexander, T.Maduskuie, K.Mcnamara, A.Smallwood, A.Wei, P.Stouten n/a ( 1AZ8 ) To be Published Unexpected Binding Mode of a Bis-Phenylamidine Factor Xa Inhibitor Complexed to Bovine Trypsin n/a n/a
1AZZ J.J.Perona, C.A.Tsu, C.S.Craik, R.J.Fletterick 5381 9154920 Biochemistry Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix. 36 1997
1B0C C.Hamiaux, J.Perez, T.Prange, S.Veesler, M.Ries-Kautt, P.Vachette 697 ( 1B0C ) J.Mol.Biol. The Bpti Decamer Observed in Acidic Ph Crystal Forms Pre-Exists as a Stable Species in Solution 297 2000
1B1U S.Gourinath, A.Srinivasan, T.P.Singh 287 ( 1B1U ) Acta Crystallogr., Sect.D Structure of the Bifunctional Inhibitor of Trypsin and Alpha-Amylase from Ragi Seeds at 2.2 Angstrom Resolution 55 2000
1BA7 P.De Meester, P.Brick, L.F.Lloyd, D.M.Blow, S.Onesti 589 9761854 Acta Crystallogr D Biol Crystallogr Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator. 54 1998
1BA8 R.Krishnan, E.Zhang, K.Hakansson, R.K.Arni, A.Tulinsky, M.S.Lim-Wilby, O.E.Levy, J.E.Semple, T.K.Brunck 12094 9724521 Biochemistry Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. 37 1998
1BB0 R.Krishnan, E.Zhang, K.Hakansson, R.K.Arni, A.Tulinsky, M.S.Lim-Wilby, O.E.Levy, J.E.Semple, T.K.Brunck 12094 9724521 Biochemistry Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. 37 1998
1BBI M.H.Werner, D.E.Wemmer 999 1734975 Biochemistry Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution. 31 1992
1BBR P.D.Martin, W.Robertson, D.Turk, R.Huber, W.Bode, B.F.Edwards 7911 1560020 J Biol Chem The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution. 267 1992
1BCU E.Conti, C.Rivetti, A.Wonacott, P.Brick 229 9559654 FEBS Lett X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin. 425 1998
1BDA M.Renatus, R.A.Engh, M.T.Stubbs, R.Huber, S.Fischer, U.Kohnert, W.Bode 4797 9305622 EMBO J Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA. 16 1997
1BEF H.M.Murthy, S.Clum, R.Padmanabhan 5573 10026173 J Biol Chem Dengue virus NS3 serine protease. Crystal structure and insights into interaction of the active site with substrates by molecular modeling and structural analysis of mutational effects. 274 1999
1BG3 A.M.Mulichak, J.E.Wilson, K.Padmanabhan, R.M.Garavito 555 9665168 Nat Struct Biol The structure of mammalian hexokinase-1. 5 1998
1BHC C.Hamiaux, T.Prange, M.Ries-Kautt, A.Ducruix, S.Lafont, J.P.Astier, S.Veesler 103 10089400 Acta Crystallogr D Biol Crystallogr The decameric structure of bovine pancreatic trypsin inhibitor (BPTI) crystallized from thiocyanate at 2.7 A resolution. 55 1999
1BHX J.Wagner, J.Kallen, C.Ehrhardt, J.P.Evenou, D.Wagner 3664 9733491 J Med Chem Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors. 41 1998
1BIK Y.Xu, P.D.Carr, J.M.Guss, D.L.Ollis 955 9566199 J Mol Biol The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains. 276 1998
1BIO H.Jing, Y.S.Babu, D.Moore, J.M.Kilpatrick, X.Y.Liu, J.E.Volanakis, S.V.Narayana 1061 ( 1BIO ) J.Mol.Biol. Structures of Native and Complexed Complement Factor D: Implications of the Atypical His57 Conformation and Self-Inhibitory Loop in the Regulation of Specific Serine Protease Activity 282 1998
1BIP S.Strobl, P.Muhlhahn, R.Bernstein, R.Wiltscheck, K.Maskos, M.Wunderlich, R.Huber, R.Glockshuber, T.A.Holak 8281 7599120 Biochemistry Determination of the three-dimensional structure of the bifunctional alpha-amylase/trypsin inhibitor from ragi seeds by NMR spectroscopy. 34 1995
1BIT G.I.Berglund, A.O.Smalas, A.Hordvik 725 ( 1BIT ) Acta Crystallogr D Biol Crystallogr STRUCTURE OF ANIONIC SALMON TRYPSIN IN A 2ND CRYSTAL FORM. 51 1995
1BJU S.Presnell, G.Patil, J.Conley, C.Mura, K.Jude, J.Bertrand, J.Powers, L.Williams n/a ( 1BJU ) To be Published Structure and Mechanism of Sulfate Ion Mediated Inhibition of Serine Proteases n/a n/a
1BJV S.R.Presnell, G.Patil, C.Mura, K.Jude, J.Conley, J.A.Bertrand, C.-M.Kam, J.C.Powers, L.D.Williams n/a ( 1BJV ) To be Published Structure and Mechanism of Sulfate Ion Mediated Inhibition of Serine Proteases n/a n/a
1BMA E.Peisach, D.Casebier, S.L.Gallion, P.Furth, G.A.Petsko, J.C.Hogan Jr., D.Ringe 66 7604279 Science Interaction of a peptidomimetic aminimide inhibitor with elastase. 269 1995
1BMM M.F.Malley, L.Tabernero, C.Y.Chang, S.L.Ohringer, D.G.Roberts, J.Das, J.S.Sack 221 8745399 Protein Sci Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090. 5 1996
1BMN M.F.Malley, L.Tabernero, C.Y.Chang, S.L.Ohringer, D.G.Roberts, J.Das, J.S.Sack 221 8745399 Protein Sci Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090. 5 1996
1BOQ R.J.Peters, A.K.Shiau, J.L.Sohl, D.E.Anderson, G.Tang, J.L.Silen, D.A.Agard 12058 9724517 Biochemistry Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease. 37 1998
1BPI S.Parkin, B.Rupp, H.Hope 18 ( 1BPI ) Acta Crystallogr D Biol Crystallogr Structure of bovine pancreatic trypsin inhibitor at 125 K: Definition of carboxyl-terminal residues Gly57 and Ala58. 52 1996
1BPT A.T.Danishefsky, D.Housset, K.S.Kim, F.Tao, J.Fuchs, C.Woodward, A.Wlodawer 577 8518731 Protein Sci Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. 2 1993
1BRA J.J.Perona, C.A.Tsu, M.E.McGrath, C.S.Craik, R.J.Fletterick 934 8478942 J Mol Biol Relocating a negative charge in the binding pocket of trypsin. 230 1993
1BRB J.J.Perona, C.A.Tsu, C.S.Craik, R.J.Fletterick 919 7683059 J Mol Biol Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI. 230 1993
1BRC J.J.Perona, C.A.Tsu, M.E.McGrath, C.S.Craik, R.J.Fletterick 934 8478942 J Mol Biol Relocating a negative charge in the binding pocket of trypsin. 230 1993
1BT7 G.Barbato, D.O.Cicero, M.C.Nardi, C.Steinkuhler, R.Cortese, R.De Francesco, R.Bazzo 370 ( 1BT7 ) J.Mol.Biol. The Solution Structure of the N-Terminal Proteinase Domain of the Hepatitis C Virus (Hcv) Ns3 Protein Provides New Insights Into its Activation and Catalytic Mechanism 289 1999
1BTH A.van de Locht, W.Bode, R.Huber, B.F.Le Bonniec, S.R.Stone, C.T.Esmon, M.T.Stubbs 2977 9214615 EMBO J The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin. 16 1997
1BTI A.T.Danishefsky, D.Housset, K.S.Kim, F.Tao, J.Fuchs, C.Woodward, A.Wlodawer 577 8518731 Protein Sci Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. 2 1993
1BTP Y.Odagaki, H.Nakai, K.Senokuchi, M.Kawamura, N.Hamanaka, M.Nakamura, K.Tomoo, T.Ishida 12849 7548040 Biochemistry Unique binding of a novel synthetic inhibitor, N-[3-[4-[4-(amidinophenoxy)carbonyl]phenyl]-2-methyl-2-propenoyl]- N-allylglycine methanesulfonate, to bovine trypsin, revealed by the crystal structure of the complex. 34 1995
1BTW B.A.Katz, J.Finermoore, R.Mortezaei, D.H.Rich, R.M.Stroud 8264 ( 1BTW ) Biochemistry EPISELECTION - NOVEL K-I-SIMILAR-TO NANOMOLAR INHIBITORS OF SERINE PROTEASES SELECTED BY BINDING OR CHEMISTRY ON AN ENZYME SURFACE. 34 1995
1BTX B.A.Katz, J.Finer-Moore, R.Mortezaei, D.H.Rich, R.M.Stroud 8264 7599119 Biochemistry Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. 34 1995
1BTY B.A.Katz, J.Finer-Moore, R.Mortezaei, D.H.Rich, R.M.Stroud 8264 7599119 Biochemistry Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. 34 1995
1BTZ B.A.Katz, J.Finer-Moore, R.Mortezaei, D.H.Rich, R.M.Stroud 8264 7599119 Biochemistry Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. 34 1995
1BXJ I.Zhukov, L.Jaroszewski, A.Bierzynski n/a ( 1BXJ ) To be Published The Conservative Mutation met-->Leu Effects Folding and Stability of Squash Trypsin Inhibitor Cmti-I n/a n/a
1BZ5 C.Hamiaux, J.Perez, T.Prange, S.Veesler, M.Ries-Kautt, P.Vachette 697 ( 1BZ5 ) J.Mol.Biol. The Bpti Decamer Observed in Acidic Ph Crystal Forms Pre-Exists as a Stable Species in Solution 297 2000
1BZX R.Helland, I.Leiros, G.I.Berglund, N.P.Willassen, A.O.Smalas 317 9760170 Eur J Biochem The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor. 256 1998
1C1N B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1N ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1O B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1O ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1P B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1P ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1Q B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1Q ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1R B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1R ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1S B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1S ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C1T B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C1T ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2A H.K.Song, Y.S.Kim, J.K.Yang, J.Moon, J.Y.Lee, S.W.Suh 1133 ( 1C2A ) J.Mol.Biol. Crystal Structure of a 16 kDa Double-Headed Bowman-Birk Trypsin Inhibitor from Barley Seeds at 1.9 A Resolution 293 1999
1C2D B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2D ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2E B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2E ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2F B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2F ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2G B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2G ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2H B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2H ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2I B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2I ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2J B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2J ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2K B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2K ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2L B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2L ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C2M B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 ( 1C2M ) Nature Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors 391 1998
1C5L B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5L ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5M B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5M ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5N B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5N ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5O B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5O ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5P B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5P ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5Q B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5Q ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5R B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5R ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5S B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5S ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5T B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5T ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5U B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5U ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5V B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5V ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5W B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5W ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5X B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5X ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase Type Plasminogen Activator 7 2000
1C5Y B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5Y ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
1C5Z B.A.Katz, R.Mackman, C.Luong, K.Radika, A.Martelli, P.A.Sprengeler, J.Wang, H.Chan, L.Wong 299 ( 1C5Z ) Chem.Biol. Structural Basis for Selectivity of a Small Molecule, S1-Binding, Submicromolar Inhibitor of Urokinase-Type Plasminogen Activator 7 2000
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1CAW T.-P.Ko, J.D.Ng, J.Day, A.Greenwood, A.McPherson n/a ( 1CAW ) To be Published Determination of Three Crystal Structures of Canavalin by Molecular Replacement n/a n/a
1CAX T.-P.Ko, J.D.Ng, J.Day, A.Greenwood, A.McPherson n/a ( 1CAX ) To be Published Determination of Three Crystal Structures of Canavalin by Molecular Replacement n/a n/a
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1CIS P.Osmark, P.Sorensen, F.M.Poulsen 11007 8218165 Biochemistry Context dependence of protein secondary structure formation: the three-dimensional structure and stability of a hybrid between chymotrypsin inhibitor 2 and helix E from subtilisin Carlsberg. 32 1993
1CJK J.J.G.Tesmer, R.K.Sunahara, R.A.Johnson, G.Gosselin, A.G.Gilman, S.R.Sprang 756 ( 1CJK ) Science Two Metal Ion Catalysis in Adenylyl Cyclase Revealed by its Complexes with ATP Analogs, Mg2+, Mn2+, and Zn2+ 285 1999
1CJT J.J.G.Tesmer, R.K.Sunahara, R.A.Johnson, G.Gosselin, A.G.Gilman, S.R.Sprang 756 ( 1CJT ) Science Two Metal Ion Catalysis in Adenylyl Cyclase Revealed by its Complexes with ATP Analogs, Mg2+, Mn2+, and Zn2+ 285 1999
1CJU J.J.G.Tesmer, R.K.Sunahara, R.A.Johnson, G.Gosselin, A.G.Gilman, S.R.Sprang 756 ( 1CJU ) Science Two Metal Ion Catalysis in Adenylyl Cyclase Revealed by its Complexes with ATP Analogs, Mg2+, Mn2+, and Zn2+ 285 1999
1CJV J.J.G.Tesmer, R.K.Sunahara, R.A.Johnson, G.Gosselin, A.G.Gilman, S.R.Sprang 756 ( 1CJV ) Science Two Metal Ion Catalysis in Adenylyl Cyclase Revealed by its Complexes with ATP Analogs, Mg2+, Mn2+, and Zn2+ 285 1999
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1DGR T.-P.Ko, A.McPherson n/a ( 1DGR ) To be Published Structures of the Rhombohedral and Orthorhombic Crystals of Canavalin from Jack Bean n/a n/a
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1E0F J.L.Richardson, B.Kroeger, W.Hoeffken, J.E.Sadler, P.Pereira, R.Huber, W.Bode, P.Fuentes-Prior 5650 ( 1E0F ) Embo J. Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor 19 2000
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1EAW R.Friedrich, W.Bode n/a ( 1EAW ) To be Published Crystal Structure of the Mtsp1 (Matriptase)-Bpti (Aprotinin) Complex n/a n/a
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1EB2 J.W.Liebeschuetz, S.D.Jones, P.J.Morgan, C.W.Murray, A.D.Rimmer, J.M.E.Roscoe, B.Waszkowycz, P.M.Welsh, W.A.Wylie, S.C.Young, H.Martin, J.Mahler, L.Brady' K.Wilkinson n/a ( 1EB2 ) To be Published Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors n/a n/a
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1EJA U.Rester, M.Moser, R.Huber, W.Bode 581 ( 1EJA ) Acta Crystallogr., Sect.D L-Isoaspartate 115 of Porcine Trypsin Promotes Crystallization of its Complex with Bdellastasin 56 2000
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1EKB D.Lu, K.Fuetterer, S.Korolev, X.Zheng, K.Tan, G.Waksman, J.E.Sadler 361 ( 1EKB ) J.Mol.Biol. Crystal Structure of Enteropeptidase Light Chain Complexed with an Analog of the Trypsinogen Activation Peptide 292 1999
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1ELT G.I.Berglund, N.P.Willassen, A.Hordvik, A.O.Smalas 925 ( 1ELT ) Acta Crystallogr D Biol Crystallogr STRUCTURE OF NATIVE PANCREATIC ELASTASE FROM NORTH-ATLANTIC SALMON AT 1.61 ANGSTROM RESOLUTION. 51 1995
1ELV C.Gaboriaud, V.Rossi, I.Bally, G.Arlaud, J.-C.Fontecilla-Camps 1755 ( 1ELV ) Embo J. Crystal Structure of the Catalytic Domain of Human Complement C1S: A Serine Protease with a Handle 19 2000
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1EYL S.Ravichandran, Dasgupta.J., C.Chakrabarti, S.Ghosh, M.Singh, J.K.Dattagupta 349 ( 1EYL ) Protein Eng. The Role of Asn14 in the Stability and Conformation of the Reactive-Site Loop of Winged Bean Chymotrypsin Inhibitor: Crystal Structure of Two Point Mutants Asn14->Lys and Asn14->Asp 14 2001
1EZQ S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol 3226 ( 1EZQ ) J.Med.Chem. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 43 2000
1EZS S.A.Gillmor, T.Takeuchi, S.Q.Yang, C.S.Craik, R.J.Fletterick 993 ( 1EZS ) J.Mol.Biol. Compromise and Accomodation in Ecotin, a Dimeric Macromolecular Inhibitor of Serine Proteases. 299 2000
1EZU S.A.Gillmor, T.Takeuchi, S.Q.Yang, C.S.Craik, R.J.Fletterick 993 ( 1EZU ) J.Mol.Biol. Compromise and Accomodation in Ecotin, a Dimeric Macromolecular Inhibitor of Serine Proteases. 299 2000
1EZX J.A.Huntington, R.J.Read, R.W.Carrell 923 ( 1EZX ) Nature Structure of a Serpin-Protease Complex Shows Inhibition by Deformation 407 2000
1F0R S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol 3226 ( 1F0R ) J.Med.Chem. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 43 2000
1F0S S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol 3226 ( 1F0S ) J.Med.Chem. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 43 2000
1F0T S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol 3226 ( 1F0T ) J.Med.Chem. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 43 2000
1F0U S.Maignan, J.P.Guilloteau, S.Pouzieux, Y.M.Choi-Sledeski, M.R.Becker, S.I.Klein, W.R.Ewing, H.W.Pauls, A.P.Spada, V.Mikol 3226 ( 1F0U ) J.Med.Chem. Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 43 2000
1F1R M.W.Vetting, J.D.Lipscomb, L.P.Wackett, L.Que Jr, D.H.Ohlendorf n/a ( 1F1R ) To be Published Structure of Homoprotocatechuate 2,3-Dioxygenase from Arthrobacter Globiformis Cm-2 : A Manganese Dependent Extradiol Dioxygenase n/a n/a
1F1U M.W.Vetting, J.D.Lipscomb, L.P.Wackett, L.Que Jr, D.H.Ohlendorf n/a ( 1F1U ) To be Published Structure of Homoprotocatechuate 2,3-Dioxygenase from Arthrobacter Globiformis Cm-2 : A Manganese Dependent Extradiol Dioxygenase n/a n/a
1F1V M.W.Vetting, J.D.Lipscomb, L.P.Wackett, L.Que Jr, D.H.Ohlendorf n/a ( 1F1V ) To be Published Structure of Homoprotocatechuate 2,3-Dioxygenase from Arthrobacter Globiformis Cm-2 : A Manganese Dependent Extradiol Dioxygenase n/a n/a
1F1X M.W.Vetting, J.D.Lipscomb, L.P.Wackett, L.Que Jr, D.H.Ohlendorf n/a ( 1F1X ) To be Published Crystal Structure of Homoprotocatechuate 2,3-Dioxygenase from Brevibacterium Fuscum n/a n/a
1F2S Y.Zhu, Q.Huang, M.Qian, Y.Jia, Y.Tang 505 ( 1F2S ) J.Protein Chem. Crystal Structure of the Complex Formed between Bovine Beta-Trypsin and Mcti-A, a Trypsin Inhibitor of Squash Family, at 1.8 A Resolution 18 1999
1F5R A.Pasternak, A.White, C.J.Jeffery, N.Medina, M.Cahoon, D.Ringe, L.Hedstrom 1331 ( 1F5R ) Protein Sci. The Energetic Cost of Induced Fit Catalysis: Crystal Structures of Trypsinogen Mutants with Enhanced Activity and Inhibitor Affinity 10 2001
1F7Z A.Pasternak, A.White, C.J.Jeffery, N.Medina, M.Cahoon, D.Ringe, L.Hedstrom 1331 ( 1F7Z ) Protein Sci. The Energetic Cost of Induced Fit Catalysis: Crystal Structures of Trypsinogen Mutants with Enhanced Activity and Inhibitor Affinity 10 2001
1FAN A.T.Danishefsky, D.Housset, K.S.Kim, F.Tao, J.Fuchs, C.Woodward, A.Wlodawer 577 8518731 Protein Sci Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. 2 1993
1FDP H.Jing, K.J.Macon, D.Moore, L.J.Delucas, J.E.Volanakis, S.V.L.Narayana 804 ( 1FDP ) Embo J. Structural Basis of Profactor D Activation: From a Highly Flexible Zymogen to a Novel Self-Inhibited Serine Protease, Complement Factor D 18 1999
1FI8 S.M.Waugh, J.L.Harris, R.J.Fletterick, C.S.Craik 758 ( 1FI8 ) Nat.Struct.Biol. The Structure of the Pro-Apoptotic Protease Granzyme B Reveals the Molecular Determinants of its Specificity. 7 2000
1FJS M.Adler, D.D.Davey, G.B.Phillips, S.H.Kim, J.Jancarik, G.Rumennik, D.L.Light, M.Whitlow 12534 ( 1FJS ) Biochemistry Preparation, Characterization and the Crystal Structure of the Inhibitor Zk-807834 (Ci-1031) Complexed with Factor Xa 39 2000
1FMG S.Deepthi, A.Johnson, V.Pattabhi 1506 ( 1FMG ) Acta Crystallogr., Sect.D Structures of Porcine [Beta]-Trypsin-Detergent Complexes: The Stabilization of Proteins Through Hydrophilic Binding of Polydocanol 57 2001
1FMZ S.Ravichandran, J.Dasgupta, C.Chakrabarti, S.Ghosh, M.Singh, J.K.Dattagupta 349 ( 1FMZ ) Protein Eng. The Role of Asn14 in the Stability and Conformation of the Reactive-Site Loop of Winged Bean Chymotrypsin Inhibitor: Crystal Structures of Two Point Mutants Asn14->Lys Asn14->Asp 14 2001
1FN0 S.Ravichandran, J.Dasgupta, C.Chakrabarti, S.Ghosh, M.Singh, J.K.Dattagupta 349 ( 1FN0 ) Protein Eng. The Role of Asn14 in the Stability and Conformation of the Reactive-Site Loop of Winged Bean Chymotrypsin Inhibitor: Crystal Structure of Two Point Mutants Asn14->Lys and Asn14->Asp 14 2001
1FN6 S.Deepthi, A.Johnson, V.Pattabhi 1506 ( 1FN6 ) Acta Crystallogr., Sect.D Structures of Porcine [Beta]-Trypsin-Detergent Complexes: The Stabilization of Proteins Through Hydrophilic Binding of Polydocanol 57 2001
1FN8 W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1FN8 ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1FNI S.Deepthi, A.Johnson, V.Pattabhi 1506 ( 1FNI ) Acta Crystallogr., Sect.D Structures of Porcine [Beta]-Trypsin-Detergent Complexes: The Stabilization of Proteins Through Hydrophilic Binding of Polydocanol 57 2001
1FPC I.I.Mathews, A.Tulinsky 550 ( 1FPC ) Acta Crystallogr D Biol Crystallogr ACTIVE-SITE MIMETIC INHIBITION OF THROMBIN. 51 1995
1FPH M.T.Stubbs, H.Oschkinat, I.Mayr, R.Huber, H.Angliker, S.R.Stone, W.Bode 187 1587268 Eur J Biochem The interaction of thrombin with fibrinogen. A structural basis for its specificity. 206 1992
1FQ3 E.Estebanez-Perpina, P.Fuentes-Prior, D.Belorgey, M.Braun, R.Kiefersauer, K.Maskos, R.Huber, H.Rubin, W.Bode 1203 ( 1FQ3 ) Biol.Chem. Crystal Structure of the Caspase Activator Human Granzyme B, a Proteinase Highly Specific for an Asp-P1 Residue 381 2000
1FUJ M.Fujinaga, M.M.Chernaia, R.Halenbeck, K.Koths, M.N.James 267 8757293 J Mol Biol The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies. 261 1996
1FXY K.P.Hopfner, E.Kopetzki, G.B.Kresse, W.Bode, R.Huber, R.A.Engh 9813 9707558 Proc Natl Acad Sci U S A New enzyme lineages by subdomain shuffling. 95 1998
1FY4 W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1FY4 ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1FY5 W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1FY5 ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1FY8 A.Pasternak, A.White, C.J.Jeffery, N.Medina, M.Cahoon, D.Ringe, L.Hedstrom 1331 ( 1FY8 ) Protein Sci. The Energetic Cost of Induced Fit Catalysis: Crystal Structures of Trypsinogen Mutants with Enhanced Activity and Inhibitor Affinity 10 2001
1G2L H.Nar, M.Bauer, A.Schmid, J.Stassen, W.Wienen, H.W.Priepke, I.K.Kauffmann, U.J.Ries, N.H.Hauel 29 ( 1G2L ) Structure Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors 9 2001
1G2M H.Nar, M.Bauer, A.Schmid, J.Stassen, W.Wienen, H.W.Priepke, I.K.Kauffmann, U.J.Ries, N.H.Hauel 29 ( 1G2M ) Structure Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors 9 2001
1G36 H.Nar, M.Bauer, A.Schmid, J.Stassen, W.Wienen, H.W.Priepke, I.K.Kauffmann, U.J.Ries, N.H.Hauel 29 ( 1G36 ) Structure Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors 9 2001
1G3B E.Toyota, K.K.S.Ng, H.Sekizaki, K.Itoh, K.Tanizawa, M.N.G.James 471 ( 1G3B ) J.Mol.Biol. X-Ray Crystallographic Analyses of Complexes between Bovine Beta-Trypsin and Schiff Base Copper(II) or Iron(III) Chelates 305 2000
1G3C E.Toyota, K.K.S.Ng, H.Sekizaki, K.Itoh, K.Tanizawa, M.N.G.James 471 ( 1G3C ) J.Mol.Biol. X-Ray Crystallographic Analyses of Complexes between Bovine Beta-Trypsin and Schiff Base Copper(II) or Iron(III) Chelates 305 2000
1G3D E.Toyota, K.K.S.Ng, H.Sekizaki, K.Itoh, K.Tanizawa, M.N.G.James 471 ( 1G3D ) J.Mol.Biol. X-Ray Crystallographic Analyses of Complexes between Bovine Beta-Trypsin and Schiff Base Copper(II) or Iron(III) Chelates 305 2000
1G3E E.Toyota, K.K.S.Ng, H.Sekizaki, K.Itoh, K.Tanizawa, M.N.G.James 471 ( 1G3E ) J.Mol.Biol. X-Ray Crystallographic Analyses of Complexes between Bovine Beta-Trypsin and Schiff Base Copper(II) or Iron(III) Chelates 305 2000
1G6X A.Addlagatta, H.Czapinska, J.Otlewski, S.Krzywda, M.Jaskolski 649 ( 1G6X ) Acta Crystallogr., Sect.D Ultrahigh-Resolution Structure of a Bpti Mutant 57 2001
1G9I G.Zhu, Q.Huang, Y.Zhu, Y.Li, C.Chi, Y.Tang 98 ( 1G9I ) Biochim.Biophys.Acta X-Ray Studies on an Artificial Mung Bean Inhibitor Complex with Bovine Beta-Trypsin in Neat Cyclohexane 1546 2001
1GBA J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBB J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBC J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBD J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBE J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBF J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBH J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBI J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBJ J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBK J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBL J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBM J.E.Mace, D.A.Agard 720 7500345 J Mol Biol Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. 254 1995
1GBT W.F.Mangel, P.T.Singer, D.M.Cyr, T.C.Umland, D.L.Toledo, R.M.Stroud, J.W.Pflugrath, R.M.Sweet 8351 2252895 Biochemistry Structure of an acyl-enzyme intermediate during catalysis: (guanidinobenzoyl)trypsin. 29 1990
1GCD M.Harel, C.T.Su, F.Frolow, Y.Ashani, I.Silman, J.L.Sussman 909 1942036 J Mol Biol Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin. 221 1991
1GCT M.M.Dixon, B.W.Matthews 7033 2819046 Biochemistry Is gamma-chymotrypsin a tetrapeptide acyl-enzyme adduct of alpha-chymotrypsin? 28 1989
1GDN W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1GDN ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1GDQ W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1GDQ ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1GDU W.R.Rypniewski, P.Oestergaard, M.Noerregaard-Madsen, M.Dauter, K.S.Wilson 8 ( 1GDU ) Acta Crystallogr., Sect.D Fusarium Oxysporum Trypsin at Atomic Resolution at 100 and 283 K: A Study of Ligand Binding 57 2001
1GFC D.Kohda, H.Terasawa, S.Ichikawa, K.Ogura, H.Hatanaka, V.Mandiyan, A.Ullrich, J.Schlessinger, F.Inagaki 1029 7881903 Structure Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. 2 1994
1GFD D.Kohda, H.Terasawa, S.Ichikawa, K.Ogura, H.Hatanaka, V.Mandiyan, A.Ullrich, J.Schlessinger, F.Inagaki 1029 7881903 Structure Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. 2 1994
1GG6 D.J.Neidhart, Y.Wei, C.Cassidy, J.Lim, W.C.Cleland, P.A.Frey n/a ( 1GG6 ) To be Published Crystal Stucture of Gamma Chymotrypsin with N-Acetyl-Phenylalanine Trifluoromethyl Ketone Bound at the Active Site n/a n/a
1GGD D.J.Neidhart, Y.Wei, C.Cassidy, J.Lim, W.C.Cleland, P.A.Frey n/a ( 1GGD ) To be Published Crystal Stucture of Gamma Chymotrypsin with N-Acetyl-Phenylalanine Trifluoromethyl Ketone Bound at the Active Site n/a n/a
1GHA H.P.Yennawar, N.H.Yennawar, G.K.Farber 577 ( 1GHA ) J Am Chem Soc A STRUCTURAL EXPLANATION FOR ENZYME MEMORY IN NONAQUEOUS SOLVENTS. 117 1995
1GHB H.P.Yennawar, N.H.Yennawar, G.K.Farber 577 ( 1GHB ) J Am Chem Soc A STRUCTURAL EXPLANATION FOR ENZYME MEMORY IN NONAQUEOUS SOLVENTS. 117 1995
1GHV B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GHV ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GHW B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GHW ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GHX B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GHX ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GHY B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GHY ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GHZ B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GHZ ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI0 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI0 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI1 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI1 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI2 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI2 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI3 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI3 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI4 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI4 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI5 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI5 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI6 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI6 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI7 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI7 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI8 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI8 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GI9 B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young 1451 ( 1GI9 ) J.Mol.Biol. A Novel Serine Protease Inhibition Motif Involving a Multi-Centered Short Hydrogen Bonding Network at the Active Site 307 2001
1GJ4 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ4 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJ5 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ5 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJ6 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ6 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJ7 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ7 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJ8 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ8 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJ9 B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJ9 ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJA B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJA ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJB B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJB ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJC B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJC ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GJD B.A.Katz, P.A.Sprengeler, C.Luong, E.Verner, K.Elrod, M.Kirtley, J.Janc, J.R.Spencer, J.G.Breitenbucher, H.Hui, D.Mcgee, D.Allen, A.Martelli, R.L.Mackman 1107 ( 1GJD ) Chem.Biol. Engineering Inhibitors Highly Selective for the S1 Sites of Ser190 Trypsin-Like Serine Protease Drug Targets 8 2002
1GL0 A.Roussel, M.Mathieu, A.Dobbs, B.Luu, C.Cambillau, C.Kellenberger 38893 ( 1GL0 ) J.Biol.Chem. Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity 276 2001
1GL1 A.Roussel, M.Mathieu, A.Dobbs, B.Luu, C.Cambillau, C.Kellenberger 38893 ( 1GL1 ) J.Biol.Chem. Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity 276 2001
1GM2 A.B.E.Brauer, G.Kelly, S.J.Matthews, R.J.Leatherbarrow 59 ( 1GM2 ) J.Biomol.Struct.Dyn. The 1H-NMR Solution Structure of the Antitryptic Core Peptide of Bowman-Birk Inhibitor Proteins: A Minimal Canonical Loop 20 2002
1GMC N.H.Yennawar, H.P.Yennawar, G.K.Farber 7326 8003497 Biochemistry X-ray crystal structure of gamma-chymotrypsin in hexane. 33 1994
1GMD N.H.Yennawar, H.P.Yennawar, G.K.Farber 7326 8003497 Biochemistry X-ray crystal structure of gamma-chymotrypsin in hexane. 33 1994
1GMH M.Harel, C.T.Su, F.Frolow, Y.Ashani, I.Silman, J.L.Sussman 909 1942036 J Mol Biol Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin. 221 1991
1GNA N.J.Skelton, K.C.Garcia, D.V.Goeddel, C.Quan, J.P.Burnier 13581 7947768 Biochemistry Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism. 33 1994
1GNB N.J.Skelton, K.C.Garcia, D.V.Goeddel, C.Quan, J.P.Burnier 13581 7947768 Biochemistry Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism. 33 1994
1GNS O.Almog, D.T.Gallagher, J.E.Ladner, S.Strausberg, P.Alexander, P.Bryan, G.L.Gilliland n/a ( 1GNS ) To be Published Structural Basis of Thermostability: Analysis of Stabilizing Mutations in Calcium Independent Subtilisin Bpn' n/a n/a
1GNV O.Almog, D.T.Gallagher, J.E.Ladner, S.Strausberg, P.Alexander, P.Bryan, G.L.Gilliland n/a ( 1GNV ) To be Published Structural Basis of Thermostability: Analysis of Stabilizing Mutations in Calcium-Independent Subtilisin n/a n/a
1GNX A.Guasch, M.Vallmitjana, R.Perez, E.Querol, J.A.Perez-Pons, M.Coll n/a ( 1GNX ) To be Published Beta-Glucosidase from Streptomyces n/a n/a
1GON A.Guasch, M.Vallmitjana, R.Perez, E.Querol, J.A.Perez-Pons, M.Coll n/a ( 1GON ) To be Published Crystal Structure of a Family 1 Beta-Glucosidase from Streptomyces n/a n/a
1H2A Y.Higuchi, T.Yagi, N.Yasuoka 1671 9438867 Structure Unusual ligand structure in Ni-Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis. 5 1997
1H2R Y.Higuchi, H.Ogata, K.Miki, N.Yasuoka, T.Yagi 549 ( 1H2R ) Structure (London) Removal of the Bridging Ligand Atom at the Ni-Fe Active Site of [Nife] Hydrogenase Upon Reduction with H2, as Revealed by X-Ray Structure Analysis at 1.4 A Resolution 7 1999
1H34 J.Debreczeni, G.Bunkoczi, B.Girmann, G.Sheldrick 393 ( 1H34 ) Acta Crystallogr.,Sect.D In-House Phase Determination of the Lima Bean Trypsin Inhibitor: A Low-Resolution Sulfur-Sad Case 59 2003
1H4W G.Katona, G.I.Berglund, J.Hajdu, L.Graf, L.Szilagyi 1209 ( 1H4W ) J.Mol.Biol. Crystal Structure Reveals Basis for the Inhibitor Resistance of Human Brain Trypsin. 315 2002
1H6K C.Mazza, M.Ohno, A.Segref, I.W.Mattaj, S.Cusack 383 ( 1H6K ) Molecular Cell Crystal Structure of the Human Nuclear CAP Binding Complex 8 2001
1H6W M.J.Van Raaij, G.Schoehn, M.R.Burda, S.Miller 1137 ( 1H6W ) J.Mol.Biol. Crystal Structure of a Heat-and Protease-Stable Part of the Bacteriophage T4 Short Tail Fibre 314 2001
1H8D E.Skordalakes, G.G.Dodson, D.S.Green, C.A.Goodwin, M.F.Scully, H.R.Hudson, V.V.Kakkar, J.J.Deadman 549 ( 1H8D ) J.Mol.Biol. Inhibition of Human Alpha-Thrombin by a Phosphonate Tripeptide Proceeds Via a Metastable Pentacoordinated Phosphorus Intermediate 311 2001
1H8I E.Skordalakes, G.G.Dodson, D.S.Green, C.A.Goodwin, M.F.Scully, H.R.Hudson, V.V.Kakkar, J.J.Deadman 549 ( 1H8I ) J.Mol.Biol. Inhibition of Human Alpha-Thrombin by a Phosphonate Tripeptide Proceeds Via a Metastable Pentacoordinated Phosphorus Intermediate 311 2001
1HA9 A.Heitz, J.-F.Hernandez, J.Gagnon, T.T.Hong, T.T.C.Pham, T.M.Nguyen, D.Le-Nguyen, L.Chiche 7973 ( 1HA9 ) Biochemistry Solution Structure of the Squash Trypsin Inhibitor Mcoti-II. A New Family for Cyclic Knottins 40 2001
1HAG J.Vijayalakshmi, K.P.Padmanabhan, K.G.Mann, A.Tulinsky 2254 7756983 Protein Sci The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. 3 1994
1HAH J.Vijayalakshmi, K.P.Padmanabhan, K.G.Mann, A.Tulinsky 2254 7756983 Protein Sci The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. 3 1994
1HAI J.Vijayalakshmi, K.P.Padmanabhan, K.G.Mann, A.Tulinsky 2254 7756983 Protein Sci The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. 3 1994
1HAO K.Padmanabhan, A.Tulinsky 272 ( 1HAO ) Acta Crystallogr D Biol Crystallogr An ambiguous structure of a DNA 15-mer thrombin complex. 52 1996
1HAP K.Padmanabhan, A.Tulinsky 272 ( 1HAP ) Acta Crystallogr D Biol Crystallogr An ambiguous structure of a DNA 15-mer thrombin complex. 52 1996
1HAV E.M.Bergmann, S.C.Mosimann, M.M.Chernaia, B.A.Malcolm, M.N.James 2436 9032381 J Virol The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition. 71 1997
1HBT P.H.Rehse, T.Steinmetzer, Y.Li, Y.Konishi, M.Cygler 11537 7547884 Biochemistry Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin. 34 1995
1HDQ J.H.Cho, S.Jeon Chung, N.-C.Ha, S.Yun, M.S.Han, H.Cheon Lee, D.H.Kim, K.Y.Choi, B.-H.Oh n/a ( 1HDQ ) To be Published Crystal Structure of Bovine Pancreatic Carboxypeptidase a Complexed with D-N-Hydroxyaminocarbonyl Phenylalanine at 2.3A n/a n/a
1HDT L.Tabernero, C.Y.Chang, S.L.Ohringer, W.F.Lau, E.J.Iwanowicz, W.C.Han, T.C.Wang, S.M.Seiler, D.G.Roberts, J.S.Sack 14 7853394 J Mol Biol Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin. 246 1995
1HDU J.H.Cho, S.Jeon Chung, N.-C.Ha, S.Yun, M.S.Han, H.Cheon Lee, D.H.Kim, K.Y.Choi, B.-H.Oh n/a ( 1HDU ) To be Published Crystal Structure of Bovine Pancreatic n/a n/a
1HEE J.H.Cho, S.Jeon Chung, N.-C.Ha, S.Yun, M.S.Han, H.Cheon Lee, D.H.Kim, K.Y.Choi, B.-H.Oh n/a ( 1HEE ) To be Published Crystal Structure of Bovine Pancreatic Carboxypeptidase a Complexed with L-N-Hydroxyaminocarbonyl Phenylalanine at 2.3 A n/a n/a
1HFD H.Jing, Y.S.Babu, D.Moore, J.M.Kilpatrick, X.Y.Liu, J.E.Volanakis, S.V.Narayana 1061 ( 1HFD ) J.Mol.Biol. Structures of Native and Complexed Complement Factor D: Implications of the Atypical His57 Conformation and Self-Inhibitory Loop in the Regulation of Specific Serine Protease Activity 282 1998
1HGT E.Skrzypczak-Jankun, V.E.Carperos, K.G.Ravichandran, A.Tulinsky, M.Westbrook, J.M.Maraganore 1379 1942057 J Mol Biol Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. 221 1991
1HIA P.R.Mittl, S.Di Marco, G.Fendrich, G.Pohlig, J.Heim, C.Sommerhoff, H.Fritz, J.P.Priestle, M.G.Grutter 253 9032072 Structure A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex. 5 1997
1HJ8 H.-K.S.Leiros, S.M.Mcsweeney, A.O.Smalas 488 ( 1HJ8 ) Acta Crystallogr.,Sect.D Atomic Resolution Structure of Trypsin Provide Insight Into Structural Radiation Damage 57 2001
1HJ9 H.-K.S.Leiros, S.M.Mcsweeney, A.O.Smalas 488 ( 1HJ9 ) Acta Crystallogr.,Sect.D Atomic Resolution Structure of Trypsin Provide Insight Into Structural Radiation Damage 57 2001
1HJA J.Ding, M.A.Qasim, M.Laskowski Junior, M.N.G.James n/a ( 1HJA ) To be Published Crystal Structure of Lys18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Alpha-Chymotrypsin at 2.3 A n/a n/a
1HKO F.W.Muskett, D.Whitford n/a ( 1HKO ) To be Published Cytochrome B5NMR Structure of Bovine n/a n/a
1HLT I.I.Mathews, K.P.Padmanabhan, A.Tulinksy, J.E.Sadler 13547 7947765 Biochemistry Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin. 33 1994
1HNR H.Shindo, T.Iwaki, R.Ieda, H.Kurumizaka, C.Ueguchi, T.Mizuno, S.Morikawa, H.Nakamura, H.Kuboniwa 125 7875316 FEBS Lett Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli. 360 1995
1HNS H.Shindo, T.Iwaki, R.Ieda, H.Kurumizaka, C.Ueguchi, T.Mizuno, S.Morikawa, H.Nakamura, H.Kuboniwa 125 7875316 FEBS Lett Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli. 360 1995
1HP7 S.-J.Kim, J.-R.Woo, E.J.Seo, M.-H.Yu, S.-E.Ryu 109 ( 1HP7 ) J.Mol.Biol. A 2.1 A Resolution Structure of an Uncleaved Alpha(1)-Antitrypsin Shows Variability of the Reactive Center and Other Loops. 306 2001
1HPG V.L.Nienaber, K.Breddam, J.J.Birktoft 11469 8105890 Biochemistry A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding. 32 1993
1HPT H.J.Hecht, M.Szardenings, J.Collins, D.Schomburg 1095 1613792 J Mol Biol Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type). 225 1992
1HQO T.C.Umland, K.L.Taylor, S.Rhee, R.B.Wickner, D.R.Davies 1459 ( 1HQO ) Proc.Nat.Acad.Sci.USA The Crystal Structure of the Nitrogen Regulation Fragment of the Yeast Prion Protein Ure2P 98 2001
1HRT J.Vitali, P.D.Martin, M.G.Malkowski, W.D.Robertson, J.B.Lazar, R.C.Winant, P.H.Johnson, B.F.Edwards 17670 1517214 J Biol Chem The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution. 267 1992
1HTM P.A.Bullough, F.M.Hughson, J.J.Skehel, D.C.Wiley 37 8072525 Nature Structure of influenza haemagglutinin at the pH of membrane fusion. 371 1994
1HUT K.Padmanabhan, K.P.Padmanabhan, J.D.Ferrara, J.E.Sadler, A.Tulinsky 17651 8102368 J Biol Chem The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. 268 1993
1HX2 K.J.Rosengren, N.L.Daly, M.J.Scanlon, D.J.Craik 4601 ( 1HX2 ) Biochemistry Solution Structure of Bsti: A New Trypsin Inhibitor from Skin Secretions of Bombina Bombina 40 2001
1HYM M.Cai, Y.Gong, O.Prakash, R.Krishnamoorthi 12087 7547948 Biochemistry Reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor-V: function, thermodynamic stability, and NMR solution structure. 34 1995
1IAU J.Rotonda, M.Garcia-Calvo, H.G.Bull, W.M.Geissler, B.M.Mckeever, C.A.Willoughby, N.A.Thornberry, J.W.Becker 357 ( 1IAU ) Chem.Biol. The Three-Dimensional Structure of Human Granzyme B Compared to Caspase-3, Key Mediators of Cell Death with Cleavage Specificity for Aspartic Acid in P1 8 2001
1IB9 M.E.Felizmenio-Quimio, N.L.Daly, D.J.Craik 22875 ( 1IB9 ) J.Biol.Chem. Circular Proteins in Plants. Solution Structure of a Novel Macrocyclic Trypsin Inhibitor from Momordica Cochinchinensis 276 2001
1ID5 S.X.Wang, C.T.Esmon, R.J.Fletterick 10038 ( 1ID5 ) Biochemistry Crystal Structure of Thrombin-Ecotin Reveals Conformational Changes and Extended Interactions 40 2001
1IFG C.T.Eggers, S.X.Wang, R.J.Fletterick, C.S.Craik 975 ( 1IFG ) J.Mol.Biol. The Role of Ecotin Dimerization in Protease Inhibition 308 2001
1IHS A.Zdanov, S.Wu, J.DiMaio, Y.Konishi, Y.Li, X.Wu, B.F.Edwards, P.D.Martin, M.Cygler 252 8272424 Proteins Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6. 17 1993
1IHT A.Zdanov, S.Wu, J.DiMaio, Y.Konishi, Y.Li, X.Wu, B.F.Edwards, P.D.Martin, M.Cygler 252 8272424 Proteins Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6. 17 1993
1IIE A.Jasanoff, G.Wagner, D.C.Wiley 6812 ( 1IIE ) Embo J. Structure of a Trimeric Domain of the Mhc Class II-Associated Chaperonin and Targeting Protein II 17 1999
1IW4 H.Hemmi, T.Yoshida, T.Kumazaki, N.Nemoto, J.Hasegawa, F.Nishioka, Y.Kyogoku, H.Yokosawa, Y.Kobayashi 10657 ( 1IW4 ) Biochemistry Solution Structure of Ascidian Trypsin Inhibitor Determined by Nuclear Magnetic Resonance Spectroscopy 41 2002
1IZ2 H.Im, M.-S.Woo, K.Y.Hwang, M.-H.Yu 46347 ( 1IZ2 ) J.Biol.Chem. Interactions Causing the Kinetic Trap in Serpin Protein Folding 277 2002
1J0Q C.Cao, Q.Zhang, L.-L.Xue, J.Ma, Y.-H.Wang, H.Wu, Z.-X.Huang 600 ( 1J0Q ) Biochem.Biophys.Res.Comm. The Solution Structure of the Oxidized Bovine Microsomal Cytochrome B5 Mutant V61H 307 2003
1J14 S.Reyda, C.Sohn, G.Klebe, K.Rall, D.Ullmann, H.D.Jakubke, M.T.Stubbs 963 ( 1J14 ) J.Mol.Biol. Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-Induced Structural Plasticity 325 2003
1J15 S.Reyda, C.Sohn, G.Klebe, K.Rall, D.Ullmann, H.D.Jakubke, M.T.Stubbs 963 ( 1J15 ) J.Mol.Biol. Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-Induced Structural Plasticity 325 2003
1J16 S.Reyda, C.Sohn, G.Klebe, K.Rall, D.Ullmann, H.D.Jakubke, M.T.Stubbs 963 ( 1J16 ) J.Mol.Biol. Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-Induced Structural Plasticity 325 2003
1J17 S.Reyda, C.Sohn, G.Klebe, K.Rall, D.Ullmann, H.D.Jakubke, M.T.Stubbs 963 ( 1J17 ) J.Mol.Biol. Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-Induced Structural Plasticity 325 2003
1J8A J.A.Cuesta-Seijo, S.Garcia-Granda n/a ( 1J8A ) To be Published Crystal Structure of Trypsin at Atomic Resolution Using Data from Laboratory Source n/a n/a
1JBL M.L.J.Korsinczky, H.J.Schirra, K.J.Rosengren, J.West, B.A.Condie, L.Otvos, M.A.Anderson, D.J.Craik 579 ( 1JBL ) J.Mol.Biol. Solution Structures by 1H NMR of the Novel Cyclic Trypsin Inhibitor Sfti-1 from Sunflower Seeds and an Acyclic Permutant 311 2001
1JBN M.L.J.Korsinczky, H.J.Schirra, K.J.Rosengren, J.West, B.A.Condie, L.Otvos, M.A.Anderson, D.J.Craik 579 ( 1JBN ) J.Mol.Biol. Solution Structures by 1H NMR of the Novel Cyclic Trypsin Inhibitor Sfti-1 from Sunflower Seeds and an Acyclic Permutant 311 2001
1JBU C.Eigenbrot, D.Kirchhofer, M.S.Dennis, L.Santell, R.A.Lazarus, J.Stamos, M.H.Ultsch 627 ( 1JBU ) Structure The Factor Vii Zymogen Structure Reveals Reregistration of Beta-Strands During Activation 9 2001
1JC6 C.Chen, C.H.Hsu, N.Y.Su, Y.C.Lin, S.H.Chiou, S.H.Wu 45079 ( 1JC6 ) J.Biol.Chem. Solution Structure of a Kunitz-Type Chymotrypsin Inhibitor Isolated from the Elapid Snake Bungarus Fasciatus 276 2001
1JIR G.Wu, G.Zhu, Q.Huang, M.Qian, Y.Tang n/a ( 1JIR ) To be Published Crystal Structure of Beta-Trypsin Complex with Amylamine in Cyclohexane n/a n/a
1JJO C.Briand, S.V.Kozlov, P.Sonderegger, M.G.Gruetter 18 ( 1JJO ) FEBS Lett. Crystal Structure of Neuroserpin: A Neuronal Serpin Involved in a Conformational Disease. 505 2001
1JRS I.V.Kurinov, R.W.Harrison 752 8845765 Protein Sci Two crystal structures of the leupeptin-trypsin complex. 5 1996
1JRT I.V.Kurinov, R.W.Harrison 752 8845765 Protein Sci Two crystal structures of the leupeptin-trypsin complex. 5 1996
1JV8 J.L.Battiste, R.Li, C.Woodward 2237 ( 1JV8 ) Biochemistry A Highly Destabilizing Mutation, G37A, of the Bovine Pancreatic Trypsin Inhibitor Retains the Average Native Conformation But Greatly Increases Local Flexibility. 41 2002
1JV9 J.L.Battiste, R.Li, C.Woodward 2237 ( 1JV9 ) Biochemistry A Highly Destabilizing Mutation, G37A, of the Bovine Pancreatic Trypsin Inhibitor Retains the Average Native Conformation But Greatly Increases Local Flexibility. 41 2002
1JXC Q.Zhao, Y.K.Chae, J.L.Markley 12284 ( 1JXC ) Biochemistry NMR Solution Structure of Attp, an Arabidopsis Thaliana Trypsin Inhibitor 41 2002
1K09 N.Carulla, C.Woodward, G.Barany 1539 ( 1K09 ) Protein Sci. Betacore, a Designed Water Soluble Four-Stranded Antiparallel B-Sheet Protein 11 2002
1K1I F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1I ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1J F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1J ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1L F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1L ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1M F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1M ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1N F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1N ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1O F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1O ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K1P F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K1P ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K21 F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K21 ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K22 F.Dullweber, M.T.Stubbs, D.Musil, J.Sturzebecher, G.Klebe 593 ( 1K22 ) J.Mol.Biol. Factorising Ligand Affinity: A Combined Thermodynamic and Crystallographic Study of Trypsin and Thrombin Inhibition 313 2001
1K2I U.Ghani, K.K.S.Ng, Atta-Ur-Rahman, M.I.Choudhary, N.Ullah, M.N.G.James 519 ( 1K2I ) J.Mol.Biol. Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin 314 2001
1K6U I.Botos, Z.Wu, W.Lu, A.Wlodawer 90 ( 1K6U ) FEBS Lett. Crystal Structure of a Cyclic Form of Bovine Pancreatic Trypsin Inhibitor. 509 2001
1K9B R.H.Voss, U.Ermler, L.O.Essen, G.Wenzl, Y.M.Kim, P.Flecker 122 ( 1K9B ) Eur.J.Biochem. Crystal Structure of the Bifunctional Soybean Bowman-Birk Inhibitor at 0.28 Nm Resolution. Structural Peculiarities in a Folded Protein Conformation 242 1996
1K9O S.Ye, A.L.Cech, R.Belmares, R.C.Bergstrom, Y.Tong, D.R.Corey, M.R.Kanost, E.J.Goldsmith 979 ( 1K9O ) Nat.Struct.Biol. The Structure of a Michaelis Serpin-Protease Complex 8 2001
1KCT H.K.Song, K.N.Lee, K.S.Kwon, M.H.Yu, S.W.Suh 150 8543039 FEBS Lett Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop. 377 1995
1KDQ E.Szabo, I.Venekei, Z.Bocskei, G.Naray-Szabo, L.Graf 1121 ( 1KDQ ) J.Mol.Biol. Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-Specific Stabilization of the Substrate-Binding Site 331 2003
1KGM Z.Gaspari, A.Patthy, L.Graf, A.Perczel 527 ( 1KGM ) Eur.J.Biochem. Comparative Structure Analysis of Proteinase Inhibitors from the Desert Locust 269 2002
1KIG A.Wei, R.S.Alexander, J.Duke, H.Ross, S.A.Rosenfeld, C.H.Chang 147 9761680 J Mol Biol Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa. 283 1998
1KIO Z.Gaspari, A.Patthy, L.Graf, A.Perczel 527 ( 1KIO ) Eur.J.Biochem. Comparative Structure Analysis of Proteinase Inhibitors from the Desert Locust 269 2002
1KJ0 Z.Gaspari, A.Patthy, L.Graf, A.Perczel 527 ( 1KJ0 ) Eur.J.Biochem. Comparative Structure Analysis of Proteinase Inhibitors from the Desert Locust 269 2002
1KLT M.E.McGrath, T.Mirzadegan, B.F.Schmidt 14318 9400368 Biochemistry Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A. 36 1997
1KSN K.R.Guertin, C.J.Gardner, S.I.Klein, A.L.Zulli, M.Czekaj, Y.Gong, A.P.Spada, D.L.Cheney, S.Maignan, J.-P.Guilloteau, K.D.Brown, D.C.Colussi, V.Chu, C.L.Heran, S.R.Morgan, R.G.Bentley, C.T.Dunwiddie, R.J.Leadley, H.W.Pauls 1671 ( 1KSN ) Bioorg.Med.Chem.Lett. Optimization of the Beta-Aminoester Class of Factor Xa Inhibitors. Part 2: Identification of Fxv673 as a Potent and Selective Inhibitor with Excellent in Vivo Anticoagulant Activity 12 2002
1KXA H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KXB H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KXC H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KXD H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KXE H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KXF H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
1KY9 T.Krojer, M.Garrido-Franco, R.Huber, M.Ehrmann, T.Clausen 455 ( 1KY9 ) Nature Crystal Structure of Degp (Htra) Reveals a Novel Protease-Chaperone Machine 416 2002
1L1N S.C.Mosimann, M.M.Chernaia, S.Sia, S.Plotch, M.N.G.James 1032 ( 1L1N ) J.Mol.Biol. Refined X-Ray Crystallographic Structure of the Poliovirus 3C Gene Product 273 1997
1L2E M.J.Bernett, S.I.Blaber, I.A.Scarisbrick, P.Dhanarajan, S.M.Thompson, M.Blaber n/a ( 1L2E ) To be Published Crystal Structure and Biochemical Characterization of Human Kallikrein 6 Reveals a Trypsin-Like Kallikrein is Expressed in the Central Nervous System n/a n/a
1LCN C.Hamiaux, S.Lafont, M.Ries-Kautt, M.C.Vaney, A.Ducruix, T.Prange n/a ( 1LCN ) To be Published Crystal Structure of Lysozyme Complexed with Thiocyanate at 1.6 Angstroms n/a n/a
1LD5 T.Cierpicki, J.Otlewski 647 ( 1LD5 ) J.Mol.Biol. NMR Structures of Two Variants of Bovine Pancreatic Trypsin Inhibitor (Bpti) Reveal Unexpected Influence of Mutations on Protein Structure and Stability 321 2002
1LD6 T.Cierpicki, J.Otlewski 647 ( 1LD6 ) J.Mol.Biol. NMR Structures of Two Variants of Bovine Pancreatic Trypsin Inhibitor (Bpti) Reveal Unexpected Influence of Mutations on Protein Structure and Stability 321 2002
1LDT M.T.Stubbs, R.Morenweiser, J.Sturzebecher, M.Bauer, W.Bode, R.Huber, G.P.Piechottka, G.Matschiner, C.P.Sommerhoff, H.Fritz, E.A.Auerswald 19931 9242660 J Biol Chem The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition. 272 1997
1LHC P.C.Weber, S.L.Lee, F.A.Lewandowski, M.C.Schadt, C.W.Chang, C.A.Kettner 3750 7893672 Biochemistry Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. 34 1995
1LHD P.C.Weber, S.L.Lee, F.A.Lewandowski, M.C.Schadt, C.W.Chang, C.A.Kettner 3750 7893672 Biochemistry Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. 34 1995
1LHE P.C.Weber, S.L.Lee, F.A.Lewandowski, M.C.Schadt, C.W.Chang, C.A.Kettner 3750 7893672 Biochemistry Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. 34 1995
1LHF P.C.Weber, S.L.Lee, F.A.Lewandowski, M.C.Schadt, C.W.Chang, C.A.Kettner 3750 7893672 Biochemistry Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. 34 1995
1LHG P.C.Weber, S.L.Lee, F.A.Lewandowski, M.C.Schadt, C.W.Chang, C.A.Kettner 3750 7893672 Biochemistry Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. 34 1995
1LKA M.S.Weiss, S.Panjikar, E.Nowak, P.A.Tucker 1407 ( 1LKA ) Acta Crystallogr., Sect.D Metal Binding to Porcine Pancreatic Elastase: Calcium or not Calcium 58 2002
1LKB M.S.Weiss, S.Panjikar, E.Nowak, P.A.Tucker 1407 ( 1LKB ) Acta Crystallogr., Sect.D Metal Binding to Porcine Pancreatic Elastase: Calcium or not Calcium 58 2002
1LMW G.Spraggon, C.Phillips, U.K.Nowak, C.P.Ponting, D.Saunders, C.M.Dobson, D.I.Stuart, E.Y.Jones 681 8591045 Structure The crystal structure of the catalytic domain of human urokinase-type plasminogen activator. 3 1995
1LO6 M.J.Bernett, S.I.Blaber, I.A.Scarisbrick, P.Dhanarajan, S.M.Thompson, M.Blaber n/a ( 1LO6 ) To be Published Crystal Structure and Biochemical Characterization of Human Kallikrein 6 Reveals a Trypsin-Like Kallikrein is Expressed in the Central Nervous System n/a n/a
1LPG H.Matter, E.Defossa, U.Heinelt, P.M.Blohm, D.Schneider, A.Mueller, S.Herok, H.Schreuder, A.Liesum, B.Brachvogel, P.Loenze, A.Walser, F.Al-Obeidi, P.Wildgoose 2749 ( 1LPG ) J.Med.Chem. Design and Quantitative Structure-Activity Relationship of 3-Amidinobenzyl-1H-Indole-2-Carboxyamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa. 45 2002
1LPK H.Matter, E.Defossa, U.Heinelt, P.M.Blohm, D.Schneider, A.Mueller, S.Herok, H.A.Schreuder, A.Liesum, V.Brachvogel, P.Loenze, A.Walser, F.Al-Obeidi, P.Wildgoose 2749 ( 1LPK ) J.Med.Chem. Design and Quantitative Structure-Activity Relationship of 3-Amidinobenzyl-1H-Indole-2-Carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa 45 2002
1LPZ H.Matter, E.Defossa, U.Heinelt, P.M.Blohm, D.Schneider, A.Mueller, S.Herok, H.A.Schreuder, A.Liesum, V.Brachvogel, P.Loenze, A.Walser, F.Al-Obeidi, P.Wildgoose 2749 ( 1LPZ ) J.Biol.Chem. Design and Quantitative Structure-Activity Relationship of 3-Amidinobenzyl-1H-Indole-2-Carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa 45 2002
1LQ8 J.A.Huntington, M.Kjellberg, J.Stenflo 205 ( 1LQ8 ) Structure Crystal Structure of Protein C Inhibitor Provides Insights Into Hormone Binding and Heparin Activation 11 2003
1LQD H.Matter, E.Defossa, U.Heinelt, P.M.Blohm, D.Schneider, A.Mueller, S.Herok, H.A.Schreuder, A.Liesum, V.Brachvogel, P.Loenze, A.Walser, F.Al-Obeidi, P.Wildgoose 2749 ( 1LQD ) J.Med.Chem. Design and Quantitative Structure-Activity Relationship of 3-Amidinobenzyl-1H-Indel-2-Carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa 45 2002
1LQE H.Matter, E.Defossa, U.Heinelt, P.M.Blohm, D.Schneider, A.Mueller, S.Herok, H.A.Schreuder, A.Liesum, V.Brachvogel, P.Loenze, A.Walser, F.Al-Obeidi, P.Wildgoose 2749 ( 1LQE ) J.Med.Chem. Design and Quantitative Structure-Activity Relationship of 3-Aminidobenzyl-1H-Indol-2-Carboxiamides as Potent, Non-Chrial, and Selective Inhibitors of Factor Xa 45 2002
1LQX J.-H.Gan, J.Wu, Z.-Q.Wang, Y.-H.Wang, Z.-X.Huang, Z.-X.Xia 1298 ( 1LQX ) Acta Crystallogr., Sect.D Structures of V45E and V45Y Mutants and Structure Comparison of a Variety of Cytochrome B5 Mutants 58 2002
1LR6 J.-H.Gan, J.Wu, Z.-Q.Wang, Y.-H.Wang, Z.-X.Huang, Z.-X.Xia 1298 ( 1LR6 ) Acta Crystallogr., Sect.D Structures of V45E and V45Y Mutants and Structure Comparison of a Variety of Cytochrome B5 Mutants 58 2002
1LTB E.A.Merritt, S.E.Pronk, T.K.Sixma, K.H.Kalk, B.A.van Zanten, W.G.Hol 88 8276119 FEBS Lett Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution. 337 1994
1LU0 R.Thaimattam, E.Tykarska, A.Bierzynski, G.M.Sheldrick, M.Jaskolski 1448 ( 1LU0 ) Acta Crystallogr., Sect.D Atomic Resolution Structure of Squash Trypsin Inhibitor: Unexpected Metal Coordination 58 2002
1LVB J.Phan, A.Zdanov, A.G.Evdokimov, J.E.Tropea, H.K.Peters III, R.B.Kapust, M.Li, A.Wlodawer, D.S.Waugh n/a ( 1LVB ) To be Published Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease n/a n/a
1LVM J.Phan, A.Zdanov, A.G.Evdokimov, J.E.Tropea, H.K.Peters III, R.B.Kapust, M.Li, A.Wlodawer, D.S.Waugh n/a ( 1LVM ) To be Published Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease n/a n/a
1LVO K.Anand, G.J.Palm, J.R.Mesters, S.G.Siddell, J.Ziebuhr, R.Hilgenfeld 3213 ( 1LVO ) Embo J. Structure of Coronavirus Main Proteinase Reveals Combination of a Chymotrypsin Fold with an Extra Alpha-Helical Domain 21 2002
1LVY M.Schiltz, W.Shepard, R.Fourme, T.Prange, E.DeLaFortelle, G.Bricogne 78 ( 1LVY ) Acta Crystallogr D Biol Crystallogr High-pressure krypton gas and statistical heavy-atom refinement: A successful combination of tools for macromolecular structure determination. 53 1997
1LW6 E.S.Radisky, D.E.Koshland Jr. 10316 ( 1LW6 ) Proc.Nat.Acad.Sci.USA A Clogged Gutter Mechanism for Protease Inhibitors 99 2002
1LZX H.Li, H.Shimizu, M.Flinspach, J.Jamal, W.Yang, M.Xian, T.Cai, E.Z.Wen, Q.Jia, P.G.Wang, T.L.Poulos 13868 ( 1LZX ) Biochemistry The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights Into No Biosynthesis 41 2002
1LZZ H.Li, H.Shimizu, M.Flinspach, J.Jamal, W.Yang, M.Xian, T.Cai, E.Z.Wen, Q.Jia, P.G.Wang, T.L.Poulos 13868 ( 1LZZ ) Biochemistry The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights Into No Biosynthesis 41 2002
1M00 H.Li, H.Shimizu, M.Flinspach, J.Jamal, W.Yang, M.Xian, T.Cai, E.Z.Wen, Q.Jia, P.G.Wang, T.L.Poulos 13868 ( 1M00 ) Biochemistry The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights Into No Biosynthesis 41 2002
1M20 P.Yao, J.Wu, Y.-H.Wang, B.-Y.Sun, Z.-X.Xia, Z.-X.Huang 4287 ( 1M20 ) Eur.J.Biochem. X-Ray Crystallography, Cd and Kinetic Studies Revealed the Essence of the Abnormal Behaviors of the Cytochrome B5 Phe35--> Try Mutant 269 2002
1M2I J.Wu, Y.-H.Wang, J.-H.Gan, W.-H.Wang, B.-Y.Sun, Z.-X.Huang, Z.-X.Xia 1225 ( 1M2I ) Chin.J.Chem. Structures of Cytochrome B5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome C 20 2002
1M2M J.Wu, Y.-H.Wang, J.-H.Gan, W.-H.Wang, B.-Y.Sun, Z.-X.Huang, Z.-X.Xia 1225 ( 1M2M ) Chin.J.Chem. Structures of Cytochrome B5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome C 20 2002
1M59 Z.-Q.Wang, J.Wu, Y.-H.Wang, W.Qian, Y.Xie, Z.-X.Xia, Z.-X.Huang 1212 ( 1M59 ) Chin.J.Chem. Proline40 is Essential to Maintaining Cytochrome B5 Stability and its Electron Transfer with Cytochrome C 20 2002
1M9U Y.Tang, D.Liang, T.Jiang, J.Zhang, L.Gui, W.Chang 57 ( 1M9U ) J.Mol.Biol. Crystal Structure of Earthworm Fibrinolytic Enzyme Component A: Revealing the Structural Determinants of its Dual Fibrinolytic Activity 321 2002
1MAX J.A.Bertrand, J.Oleksyszyn, C.M.Kam, B.Boduszek, S.Presnell, R.R.Plaskon, F.L.Suddath, J.C.Powers, L.D.Williams 3147 8605148 Biochemistry Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. 35 1996
1MAY J.A.Bertrand, J.Oleksyszyn, C.M.Kam, B.Boduszek, S.Presnell, R.R.Plaskon, F.L.Suddath, J.C.Powers, L.D.Williams 3147 8605148 Biochemistry Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. 35 1996
1MBM I.H.Barrette-Ng, K.K.-S.Ng, B.L.Mark, D.Van Aken, M.M.Cherney, C.Garen, Y.Kolodenko, A.E.Gorbalenya, E.J.Snijder, M.N.G.James 39960 ( 1MBM ) J.Biol.Chem. Structure of Arterivirus Nsp4: The Smallest Chymotrypsin-Like Proteinase with an Alpha/Beta C-Terminal Extension and Alternate Conformations of the Oxyanion Hole 277 2002
1MBQ E.Toyota, K.K.S.Ng, S.Kuninaga, H.Sekizaki, K.Itoh, K.Tanizawa, M.N.G.James 391 ( 1MBQ ) J.Mol.Biol. Crystal Structure and Nucleotide Sequence of an Anionic Trypsin from Chum Salmon (Oncorhynchus Keta) in Comparison with Atlantic Salmon (Salmo Salar) and Bovine Trypsin 324 2002
1MCT Q.Huang, S.Liu, Y.Tang 1022 8445634 J Mol Biol Refined 1.6 A resolution crystal structure of the complex formed between porcine beta-trypsin and MCTI-A, a trypsin inhibitor of the squash family. Detailed comparison with bovine beta-trypsin and its complex. 229 1993
1MCV J.Ay, K.Hilpert, N.Krauss, J.Schneider-Mergener, W.Hoehne 247 ( 1MCV ) Acta Crystallogr., Sect.D Structure of a Hybrid Squash Inhibitor in Complex with Porcine Pancreatic Elastase at 1.8 A Resolution 59 2003
1MIT J.Liu, O.Prakash, M.Cai, Y.Gong, Y.Huang, L.Wen, J.J.Wen, J.K.Huang, R.Krishnamoorthi 1516 8634282 Biochemistry Solution structure and backbone dynamics of recombinant Cucurbita maxima trypsin inhibitor-V determined by NMR spectroscopy. 35 1996
1MKW M.G.Malkowski, P.D.Martin, J.C.Guzik, B.F.Edwards 1438 9232645 Protein Sci The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding. 6 1997
1MKX M.G.Malkowski, P.D.Martin, J.C.Guzik, B.F.Edwards 1438 9232645 Protein Sci The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding. 6 1997
1MMJ T.Kinoshita, I.Nakanishi, A.Sato, T.Tada 21 ( 1MMJ ) Bioorg.Med.Chem.Lett. True Interaction Mode of Porcine Pancreatic Elastase with Fr136706, a Potent Peptidyl Inhibitor 13 2003
1MMV L.E.Bretscher, H.Li, T.L.Poulos, O.W.Griffith n/a ( 1MMV ) To be Published Structural Characterization and Kinetics of Nitric Oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-Ornithines n/a 2003
1MMW L.E.Bretscher, H.Li, T.L.Poulos, O.W.Griffith n/a ( 1MMW ) To be Published Structural Characterization and Kinetics of Nitric Oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-Ornithines n/a 2003
1MSK M.M.Dixon, S.Huang, R.G.Matthews, M.Ludwig 1263 8939751 Structure The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12. 4 1996
1MTN C.Capasso, M.Rizzi, E.Menegatti, P.Ascenzi, M.Bolognesi 26 9179777 J Mol Recognit Crystal structure of the bovine alpha-chymotrypsin:Kunitz inhibitor complex. An example of multiple protein:protein recognition sites. 10 1997
1MTS M.T.Stubbs, R.Huber, W.Bode 103 7498454 FEBS Lett Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. 375 1995
1MTU M.T.Stubbs, R.Huber, W.Bode 103 7498454 FEBS Lett Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. 375 1995
1MTV M.T.Stubbs, R.Huber, W.Bode 103 7498454 FEBS Lett Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. 375 1995
1MTW M.T.Stubbs, R.Huber, W.Bode 103 7498454 FEBS Lett Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. 375 1995
1N6X R.B.G.Ravelli, H.K.Schroder Leiros, B.Pan, M.Caffrey, S.Mcsweeney 217 ( 1N6X ) Structure Specific Radiation-Damage Can be Used to Solve Macromolecular Crystal Structures 11 2003
1N6Y R.B.G.Ravelli, H.K.Schroder Leiros, B.Pan, M.Caffrey, S.Mcsweeney 217 ( 1N6Y ) Structure Specific Radiation-Damage Can be Used to Solve Macromolecular Crystal Structures 11 2003
1N7A R.B.G.Ravelli, H.K.Schroder Leiros, B.Pan, M.Caffrey, S.Mcsweeney 217 ( 1N7A ) Structure Specific Radiation-Damage Can be Used to Solve Macromolecular Crystal Structures 11 2003
1N7B R.B.G.Ravelli, H.K.Schroder Leiros, B.Pan, M.Caffrey, S.Mcsweeney 217 ( 1N7B ) Structure Specific Radiation-Damage Can be Used to Solve Macromolecular Crystal Structures 11 2003
1N8O C.Cambillau, S.Spinelli, M.Lauwereys n/a ( 1N8O ) To be Published Crystal Structure of a Complex between Bovine Chymotrypsin and Ecotin at 2.0 A Resolution n/a n/a
1NAG A.T.Danishefsky, D.Housset, K.S.Kim, F.Tao, J.Fuchs, C.Woodward, A.Wlodawer 577 8518731 Protein Sci Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. 2 1993
1NC6 M.J.Costanzo, S.C.Yabut, H.R.Almond Jr., P.Andrade-Gordon, T.W.Corcoran, L.De Garavilla, J.A.Kauffman, W.M.Abraham, R.Recacha, D.Chattopadhyay, B.E.Maryanoff 3865 ( 1NC6 ) J.Med.Chem. Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone. 46 2003
1NES E.F.Meyer Jr., R.Radhakrishnan, G.M.Cole, L.G.Presta 533 3640831 J Mol Biol Structure of the product complex of acetyl-Ala-Pro-Ala with porcine pancreatic elastase at 1.65 A resolution. 189 1986
1NKX S.Sharma, J.Jasti, J.Kumar, A.K.Mohanty, T.P.Singh 485 ( 1NKX ) J.Mol.Biol. Crystal Structure of a Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution 331 2003
1NN6 K.K.Reiling, J.Krucinski, L.J.Miercke, W.W.Raymond, G.H.Caughey, R.M.Stroud 2616 ( 1NN6 ) Biochemistry Structure of Human Pro-Chymase: A Model for the Activating Transition of Granule-Associated Proteases. 42 2003
1NRN I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NRO I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NRP I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NRQ I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NRR I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NRS I.I.Mathews, K.P.Padmanabhan, V.Ganesh, A.Tulinsky, M.Ishii, J.Chen, C.W.Turck, S.R.Coughlin, .2.Fenton 2nd 3266 8136362 Biochemistry Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. 33 1994
1NTP A.A.Kossiakoff 281 ( 1NTP ) Basic Life Sci. Use of the Neutron Diffraction-H(Slash)D Exchange Technique to Determine the Conformational Dynamics of Trypsin 27 1984
1O2G B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2G ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2H B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2H ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2I B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2I ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2J B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2J ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2K B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2K ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2L B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2L ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2M B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2M ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2N B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2N ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2O B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2O ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2P B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2P ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 329 2003
1O2Q B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2Q ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2R B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2R ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2S B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2S ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2T B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2T ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2U B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2U ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2V B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2V ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2W B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2W ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2X B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2X ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2Y B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2Y ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O2Z B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O2Z ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O30 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O30 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O31 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O31 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O32 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O32 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O33 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O33 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O34 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O34 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O35 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O35 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O36 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O36 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O37 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O37 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O38 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O38 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O39 B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O39 ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3A B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3A ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3B B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3B ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3C B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3C ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3D B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3D ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3E B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3E ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3F B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3F ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3G B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3G ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3H B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3H ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3I B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3I ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3J B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3J ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3K B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3K ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3L B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3L ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3M B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3M ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3N B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3N ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3O B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3O ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O3P B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc 93 ( 1O3P ) J.Mol.Biol. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors. 329 2003
1O8Y U.Marx, M.Korsinczky, H.Schirra, A.Jones, B.Condie, L.Otvos, D.Craik 21782 ( 1O8Y ) J.Biol.Chem. Enzymatic Cyclization of a Potent Bowman-Birk Protease Inhibitor, Sunflower Trypsin Inhibitor-1, and Solution Structure of an Acyclic Precursor Peptide 278 2003
1O8Z U.Marx, M.Korsinczky, H.Schirra, A.Jones, B.Condie, L.Otvos, D.Craik 21782 ( 1O8Z ) J.Biol.Chem. Enzymatic Cyclization of a Potent Bowman-Birk Protease Inhibitor, Sunflower Trypsin Inhibitor-1, and Solution Structure of an Acyclic Precursor Peptide 278 2003
1OA5 M.P.Williamson, K.Akasaka, M.Refaee 1971 ( 1OA5 ) Protein Sci. The Solution Structure of Bovine Pancreatic Trypsin Inhibitor at High Pressure 12 2003
1OA6 M.P.Williamson, K.Akasaka, M.Refaee 1971 ( 1OA6 ) Protein Sci. The Solution Structure of Bovine Pancreatic Trypsin Inhibitor at High Pressure 12 2003
1OIS N.Lue, A.Sharma, A.Mondragon, J.C.Wang 1315 8747458 Structure A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications. 3 1995
1OO8 A.Dementiev, M.Simonovic, K.Volz, P.G.W.Gettins n/a ( 1OO8 ) To be Published Canonical Inhibitor-Like Interactions Explain Reactivity of Alpha-1-Pi Pittsburgh and Antithrombin with Proteinases n/a n/a
1OPH A.Dementiev, M.Simonovic, K.Volz, P.G.W.Gettins n/a ( 1OPH ) To be Published Canonical Inhibitor-Like Interactions Explain Reactivity of Alpha-1-Pi Pittsburgh and Antithrombin with Proteinases n/a n/a
1OS1 A.Sudom, R.Walters, L.Pastushok, D.Goldie, L.Prasad, L.T.Delbaere, H.Goldie 4233 ( 1OS1 ) J.Bacteriol. Mechanisms of Activation of Phosphoenolpyruvate Carboxykinase from Escherichia Coli by Ca2+ and of Desensitization by Trypsin. 185 2003
1OS8 M.J.Page, S.L.Wong, J.Hewitt, N.C.Strynadka, R.T.Macgillivray 9060 ( 1OS8 ) Biochemistry Engineering the Primary Substrate Specificity of Streptomyces Griseus Trypsin. 42 2003
1OSS M.J.Page, S.L.Wong, J.Hewitt, N.C.Strynadka, R.T.Macgillivray 9060 ( 1OSS ) Biochemistry Engineering the Primary Substrate Specificity of Streptomyces Griseus Trypsin. 42 2003
1OVA P.E.Stein, A.G.Leslie, J.T.Finch, R.W.Carrell 941 1942038 J Mol Biol Crystal structure of uncleaved ovalbumin at 1.95 A resolution. 221 1991
1OVO E.Papamokos, E.Weber, W.Bode, R.Huber, M.W.Empie, I.Kato, M.Laskowski Jr. 515 6752426 J Mol Biol Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases. 158 1982
1OYQ H.Nar, M.Bauer, A.Schmid, J.Stassen, W.Wienen, H.W.Priepke, I.K.Kauffmann, U.J.Ries, N.H.Hauel 29 ( 1OYQ ) Structure Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors 9 2001
1P01 R.Bone, A.B.Shenvi, C.A.Kettner, D.A.Agard 7609 3122831 Biochemistry Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid. 26 1987
1P02 R.Bone, D.Frank, C.A.Kettner, D.A.Agard 7600 2611204 Biochemistry Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. 28 1989
1P03 R.Bone, D.Frank, C.A.Kettner, D.A.Agard 7600 2611204 Biochemistry Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. 28 1989
1P04 R.Bone, D.Frank, C.A.Kettner, D.A.Agard 7600 2611204 Biochemistry Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. 28 1989
1P05 R.Bone, D.Frank, C.A.Kettner, D.A.Agard 7600 2611204 Biochemistry Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. 28 1989
1P06 R.Bone, D.Frank, C.A.Kettner, D.A.Agard 7600 2611204 Biochemistry Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. 28 1989
1P09 R.Bone, J.L.Silen, D.A.Agard 191 2716847 Nature Structural plasticity broadens the specificity of an engineered protease. 339 1989
1P10 R.Bone, J.L.Silen, D.A.Agard 191 2716847 Nature Structural plasticity broadens the specificity of an engineered protease. 339 1989
1P11 R.Bone, N.S.Sampson, P.A.Bartlett, D.A.Agard 2263 1998685 Biochemistry Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. 30 1991
1P12 R.Bone, N.S.Sampson, P.A.Bartlett, D.A.Agard 2263 1998685 Biochemistry Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. 30 1991
1PBI I.Li de la Sierra, L.Quillien, P.Flecker, J.Gueguen, S.Brunie 1195 9887273 J Mol Biol Dimeric crystal structure of a Bowman-Birk protease inhibitor from pea seeds. 285 1999
1PI2 P.Chen, J.Rose, R.Love, C.H.Wei, B.C.Wang 1990 1730730 J Biol Chem Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors. 267 1992
1PIT K.D.Berndt, P.Guntert, L.P.Orbons, K.Wuthrich 757 1383552 J Mol Biol Determination of a high-quality nuclear magnetic resonance solution structure of the bovine pancreatic trypsin inhibitor and comparison with three crystal structures. 227 1992
1PMC G.Mer, H.Hietter, C.Kellenberger, M.Renatus, B.Luu, J.F.Lefevre 158 8613985 J Mol Biol Solution structure of PMP-C: a new fold in the group of small serine proteinase inhibitors. 258 1996
1PPB W.Bode, I.Mayr, U.Baumann, R.Huber, S.R.Stone, J.Hofsteenge 3467 2583108 EMBO J The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. 8 1989
1PPC W.Bode, D.Turk, J.Sturzebecher 175 2226434 Eur J Biochem Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydro-8- quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-thrombin. X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin. 193 1990
1PPE W.Bode, H.J.Greyling, R.Huber, J.Otlewski, T.Wilusz 285 2914611 FEBS Lett The refined 2.0 A X-ray crystal structure of the complex formed between bovine beta-trypsin and CMTI-I, a trypsin inhibitor from squash seeds (Cucurbita maxima). Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes. 242 1989
1PPF W.Bode, A.Z.Wei, R.Huber, E.Meyer, J.Travis, S.Neumann 2453 3640709 EMBO J X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. 5 1986
1PPH D.Turk, J.Sturzebecher, W.Bode 133 1879520 FEBS Lett Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes. 287 1991
1PSI P.R.Elliott, D.A.Lomas, R.W.Carrell, J.P.Abrahams 676 8756325 Nat Struct Biol Inhibitory conformation of the reactive loop of alpha 1-antitrypsin. 3 1996
1PXX S.W.Rowlinson, J.R.Kiefer, J.Prusakiewicz, J.L.Pawlitz, K.R.Kozak, A.S.Kalgutkar, W.C.Stallings, R.G.Kurumbail, L.J.Marnett n/a ( 1PXX ) To be Published A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385 n/a n/a
1PYT F.X.Gomis-Ruth, M.Gomez, W.Bode, R.Huber, F.X.Aviles 4387 7556081 EMBO J The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C. 14 1995
1Q0O M.W.Vetting, L.P.Wackett, L.Que, J.D.Lipscomb, D.H.Ohlendorf n/a ( 1Q0O ) To be Published A Crystallographic Comparison of Manganese and Iron Dependent Homoprotocatechuate 2,3-Dioxygenase n/a n/a
1QA0 M.Whitlow, D.O.Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QA0 ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QA7 E.M.Bergmann, M.M.Cherney, J.Mckendrick, J.C.Vederas, M.N.G.James 153 ( 1QA7 ) Virology Crystal Structure of an Inhibitor Complex of the 3C Proteinase from Hepatitis a Virus (Hav)and Implications for the Polyprotein Processing in Hav 265 1999
1QB1 M.Whitlow, D.O Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QB1 ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QB6 M.Whitlow, D.O.Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QB6 ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QB9 M.Whitlow, D.O.Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QB9 ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QBN M.Whitlow, D.O Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QBN ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QBO M.Whitlow, D.O.Arnaiz, B.O.Buckman, D.D.Davey, B.Griedel, W.J.Guilford, S.K.Koovakkat, A.Liang, R.Mohan, G.B.Phillips, M.Seto, K.J.Shaw, W.Xu, Z.Zhao, D.R.Light, M.M.Morrissey 1395 ( 1QBO ) Acta Crystallogr., Sect.D Crystallographic Analysis of Potent and Selective Factor Xa Inhibitors Complexed to Bovine Trypsin 55 1999
1QCP R.Recacha, M.Carson, M.J.Costanzo, B.Maryanoff, L.J.Delucas, D.Chattopadhyay 1785 ( 1QCP ) Acta Crystallogr., Sect.D Structure of the Rwj-51084-Bovine Pancreatic Beta-Trypsin Complex at 1.8 A 55 1999
1QG1 K.Ogura, S.Tsuchiya, H.Terasawa, S.Yuzawa, H.Hatanaka, V.Mandiyan, J.Schlessinger, F.Inagaki 439 ( 1QG1 ) J.Mol.Biol. Solution Structure of the Sh2 Domain of Grb2 Complexed with the Shc Derived Phosphotyrosine Containing Peptide 289 1999
1QH2 M.C.Lee, M.J.Scanlon, D.J.Craik, M.A.Anderson 526 10360353 Nat Struct Biol A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein. 6 1999
1QHR H.Jhoti, A.Cleasby, S.Reid, P.Thomas, M.Weir, A.Wonacott 7969 ( 1QHR ) Biochemistry Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template 38 1999
1QIX R.C.Wilmouth, I.J.Clifton, C.V.Robinson, P.L.Roach, R.T.Aplin, N.J.Westwood, J.Hajdu, C.J.Schofield 456 ( 1QIX ) Nat.Struct.Biol. Structure of a Specific Acyl-Enzyme Complex Formed between Beta-Casomorphin-7 and Porcine Pancreatic Elastase 4 1997
1QJ1 H.Jhoti, A.Cleasby, S.Reid, P.Thomas, M.Weir, A.Wonacott 7969 ( 1QJ1 ) Biochemistry Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template 38 1999
1QJ6 H.Jhoti, A.Cleasby, S.Reid, P.Thomas, M.Weir, A.Wonacott 7969 ( 1QJ6 ) Biochemistry Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template 38 1999
1QJ7 H.Jhoti, A.Cleasby, S.Reid, P.Thomas, M.Weir, A.Wonacott 7969 ( 1QJ7 ) Biochemistry Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template 38 1999
1QL7 M.T.Stubbs, S.Reyda, F.Dullweber, M.Moeller, G.Klebe, K.D.Ullmann, H.D.Jakubke, D.Dorsch, W.W.K.R.Mederski, H.Wurzig n/a ( 1QL7 ) To be Published A Case of Molecular Memory: Unexpected Binding Mode Induces a Factor Xa-Like Conformation in Trypsin n/a n/a
1QL8 M.T.Stubbs, S.Reyda, F.Dullweber, M.Moeller, G.Klebe, K.D.Ullmann, H.D.Jakubke, D.Dorsch, W.W.K.R.Mederski, H.Wurzig n/a ( 1QL8 ) To be Published A Case of Molecular Memory: Unexpected Binding Mode Induces a Factor Xa-Like Conformation in Trypsin n/a n/a
1QL9 M.T.Stubbs, S.Reyda, F.Dullweber, M.Moeller, G.Klebe, K.D.Ullmann, H.D.Jakubke, D.Dorsch, W.W.K.R.Mederski, H.Wurziger n/a ( 1QL9 ) To be Published A Case of Molecular Memory: Unexpected Binding Mode Induces a Factor Xa-Like Conformation in Trypsin n/a n/a
1QLP P.R.Elliott, X.Y.Pei, T.Dafforn, D.A.Lomas 1274 ( 1QLP ) Protein Sci. Topography of a 2.0 A Structure of Alpha1-Antitrypsin Reveals Targets for Rational Drug Design to Prevent Conformational Disease. 9 2000
1QLQ H.Czapinska, J.Otlewski, S.Krzywda, G.M.Sheldrick, M.Jaskolski 1237 ( 1QLQ ) J.Mol.Biol. High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence 295 1999
1QMB J.A.Huntington, N.S.Pannu, B.Hazes, R.J.Read, D.A.Lomas, R.W.Carrell 449 ( 1QMB ) J.Mol.Biol. A 2.6A Structure of a Serpin Polymer and Implications for Conformational Disease 293 1999
1QMN B.Gooptu, B.Hazes, W.-S.W.Chang, T.R.Dafforn, R.W.Carrell, R.J.Read, D.A.Lomas 67 ( 1QMN ) Proc.Nat.Acad.Sci.USA Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two- Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease 97 2000
1QNJ M.Wurtele, M.Hahn, K.Hilpert, W.Hohne 520 ( 1QNJ ) Acta Crystallogr.,Sect.D Atomic Resolution Structure of Native Porcine Pancreatic Elastase at 1.1 A 56 2000
1QQU A.Johnson, N.Gautham, V.Pattabhi 7 ( 1QQU ) Biochim.Biophys.Acta Crystal Structure at 1.63 A Resolution of the Native Form of Porcine Beta- Trypsin: Revealing an Acetate Ion Binding Site and Functional Water Network 1435 1999
1QRZ E.Peisach, J.Wang, T.De Los Santos, E.Reich, D.Ringe 11180 ( 1QRZ ) Biochemistry Crystal Structure of the Proenzyme Domain of Plasminogen 38 1999
1QUR T.Steinmetzer, M.Renatus, S.Kuenzel, A.Eichinger, W.Bode, P.Wikstroem, J.Hauptmann, J.Stuerzebecher 598 ( 1QUR ) Eur.J.Biochem. Design and Evaluation of Novel Bivalent Thrombin Inhibitors Based on Amidinophenylalanines 265 1999
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1TFX M.J.Burgering, L.P.Orbons, A.van der Doelen, J.Mulders, H.J.Theunissen, P.D.Grootenhuis, W.Bode, R.Huber, M.T.Stubbs 395 9199408 J Mol Biol The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. 269 1997
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1THP E.R.Guinto, S.Caccia, T.Rose, K.Futterer, G.Waksman, E.Di Cera 1852 10051558 Proc Natl Acad Sci U S A Unexpected crucial role of residue 225 in serine proteases. 96 1999
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1TMQ S.Strobl, K.Maskos, G.Wiegand, R.Huber, F.X.Gomis-Ruth, R.Glockshuber 911 9687373 Structure A novel strategy for inhibition of alpha-amylases: yellow meal worm alpha-amylase in complex with the Ragi bifunctional inhibitor at 2.5 A resolution. 6 1998
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1TNG I.V.Kurinov, R.W.Harrison 735 7634078 Nat Struct Biol Prediction of new serine proteinase inhibitors. 1 1994
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1UCY P.D.Martin, M.G.Malkowski, J.DiMaio, Y.Konishi, F.Ni, B.F.Edwards 13030 8855938 Biochemistry Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues. 35 1996
1UEA F.X.Gomis-Ruth, K.Maskos, M.Betz, A.Bergner, R.Huber, K.Suzuki, N.Yoshida, H.Nagase, K.Brew, G.P.Bourenkov, H.Bartunik, W.Bode 77 9288970 Nature Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. 389 1997
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1VCP H.K.Choi, G.Lu, S.Lee, G.Wengler, M.G.Rossmann 345 9094737 Proteins Structure of Semliki Forest virus core protein. 27 1997
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1VIE N.Narayana, D.A.Matthews, E.E.Howell, X.Nguyen-huu 1018 7583655 Nat Struct Biol A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. 2 1995
1VIF N.Narayana, D.A.Matthews, E.E.Howell, X.Nguyen-huu 1018 7583655 Nat Struct Biol A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. 2 1995
1VIT J.Vitali, P.D.Martin, M.G.Malkowski, C.M.Olsen, P.H.Johnson, B.F.P.Edwards 453 ( 1VIT ) Acta Crystallogr D Biol Crystallogr Structure of a bovine thrombin-hirudin(51-65) complex determined by a combination of molecular replacement and graphics. Incorporation of known structural information in molecular replacement. 52 1996
1VPN T.Stehle, S.C.Harrison n/a ( 1VPN ) To be Published Crystal Structure of a Polyomavirus Vp1-Oligosaccharide Complex at 1.9 A Resolution n/a n/a
1VPS T.Stehle, S.C.Harrison n/a ( 1VPS ) To be Published Crystal Structure of a Polyomavirus Vp1-Oligosaccharide Complex at 1.9 A Resolution n/a n/a
1VSB V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
1VTP K.J.Nielsen, J.M.Hill, M.A.Anderson, D.J.Craik 369 8555206 Biochemistry Synthesis and structure determination by NMR of a putative vacuolar targeting peptide and model of a proteinase inhibitor from Nicotiana alata. 35 1996
1WBC J.K.Dattagupta, C.Chakrabarti, A.Podder, S.K.Dutta, M.Singh 229 2254924 J Mol Biol Crystallization and preliminary X-ray studies of psophocarpin B1, a chymotrypsin inhibitor from winged bean seeds. 216 1990
1WYK S.Lee, R.J.Kuhn, M.G.Rossmann 311 9779796 Proteins Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building. 33 1998
1XKA K.Kamata, H.Kawamoto, T.Honma, T.Iwama, S.H.Kim 6630 9618463 Proc Natl Acad Sci U S A Structural basis for chemical inhibition of human blood coagulation factor Xa. 95 1998
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1XUF B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1XUG B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1XUH B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1XUI B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1XUJ B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1XUK B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud 608 9468142 Nature Design of potent selective zinc-mediated serine protease inhibitors. 391 1998
1YCP M.G.Malkowski, P.D.Martin, S.T.Lord, B.F.Edwards 815 9307032 Biochem J Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16. 326 1997
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1YPA Y.Harpaz, N.Elmasry, A.R.Fersht, K.Henrick 311 8278384 Proc Natl Acad Sci U S A Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. 91 1994
1YPB Y.Harpaz, N.Elmasry, A.R.Fersht, K.Henrick 311 8278384 Proc Natl Acad Sci U S A Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. 91 1994
1YPC Y.Harpaz, N.Elmasry, A.R.Fersht, K.Henrick 311 8278384 Proc Natl Acad Sci U S A Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. 91 1994
1YYY R.Krishnan, E.Zhang, K.Hakansson, R.K.Arni, A.Tulinsky, M.S.Lim-Wilby, O.E.Levy, J.E.Semple, T.K.Brunck 12094 9724521 Biochemistry Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. 37 1998
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2ACH U.Baumann, R.Huber, W.Bode, D.Grosse, M.Lesjak, C.B.Laurell 595 2016749 J Mol Biol Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins. 218 1991
2BBI M.H.Werner, D.E.Wemmer 999 1734975 Biochemistry Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution. 31 1992
2BTC R.Helland, G.I.Berglund, J.Otlewski, W.Apostoluk, O.A.Andersen, N.P.Willassen, A.O.Smalas 139 ( 2BTC ) Acta Crystallogr., Sect.D High Resolution Structures of Three New Trypsin-Squash-Inhibitor Complexes: A Detailed Comparison with Other Trypsins and Their Complexes 55 1999
2BZA N.Ota, C.Stroupe, J.M.S.Ferreira-Da-Silva, S.S.Shah, M.Mares-Guia, A.T.Brunger 641 ( 2BZA ) Proteins: Struct., Funct., Genet. Non-Boltzmann Thermodynamic Integration (Nbti) for Macromolecular Systems: Relative Free Energy of Binding of Trypsin to Benzamidine and Benzylamine 37 1999
2CAU T.-P.Ko, J.Day, A.Macpherson 411 ( 2CAU ) Acta Crystallogr., Sect.D The Refined Structure of Canavalin from Jack Bean in Two Crystal Forms at 2.1 And 2.0 Angstrom Resolution 56 2000
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2CHA J.J.Birktoft, D.M.Blow 187 ( 2CHA ) J.Mol.Biol. The Structure of Crystalline Alpha-Chymotrypsin, V.The Atomic Structure of Tosyl-Alpha-Chymotrypsin at 2 Angstroms Resolution 68 1972
2CI2 C.A.McPhalen, M.N.James 261 3828302 Biochemistry Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds. 26 1987
2CTI T.A.Holak, D.Gondol, J.Otlewski, T.Wilusz 635 2614837 J Mol Biol Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing. 210 1989
2EST D.L.Hughes, L.C.Sieker, J.Bieth, J.L.Dimicoli 645 6926029 J Mol Biol Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase. 162 1982
2ETI L.Chiche, C.Gaboriaud, A.Heitz, J.P.Mornon, B.Castro, P.A.Kollman 405 2622910 Proteins Use of restrained molecular dynamics in water to determine three-dimensional protein structure: prediction of the three-dimensional structure of Ecballium elaterium trypsin inhibitor II. 6 1989
2GCH G.H.Cohen, E.W.Silverton, D.R.Davies 449 6914398 J Mol Biol Refined crystal structure of gamma-chymotrypsin at 1.9 A resolution. Comparison with other pancreatic serine proteases. 148 1981
2GCT M.M.Dixon, R.G.Brennan, B.W.Matthews 89 1888717 Int J Biol Macromol Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH. 13 1991
2GMT K.Kreutter, A.C.Steinmetz, T.C.Liang, M.Prorok, R.H.Abeles, D.Ringe 13792 7947790 Biochemistry Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones. 33 1994
2HEX J.Lubkowski, A.Wlodawer 335 10089443 Acta Crystallogr D Biol Crystallogr Decamers observed in the crystals of bovine pancreatic trypsin inhibitor. 55 1999
2HGT E.Skrzypczak-Jankun, V.E.Carperos, K.G.Ravichandran, A.Tulinsky, M.Westbrook, J.M.Maraganore 1379 1942057 J Mol Biol Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. 221 1991
2HNT T.J.Rydel, M.Yin, K.P.Padmanabhan, D.T.Blankenship, A.D.Cardin, P.E.Correa, .2.Fenton 2nd, A.Tulinsky 22000 8071320 J Biol Chem Crystallographic structure of human gamma-thrombin. 269 1994
2HPP R.K.Arni, K.Padmanabhan, K.P.Padmanabhan, T.P.Wu, A.Tulinsky 4727 8387813 Biochemistry Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin. 32 1993
2HPQ R.K.Arni, K.Padmanabhan, K.P.Padmanabhan, T.P.Wu, A.Tulinsky 4727 8387813 Biochemistry Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin. 32 1993
2KAI Z.Chen, W.Bode 283 ( 2KAI ) J.Mol.Biol. Refined 2.5 Angstroms X-Ray Crystal Structure of the Complex Formed by Porcine Kallikrein a and the Bovine Pancreatic Trypsin Inhibitor. Crystallization, Patterson Search, Structure Determination, Refinement, Structure and Comparison with its Components and with the Bovine Trypsin-Pancreatic Trypsin Inhibitor Complex 164 1983
2LET K.J.Nielsen, D.Alewood, J.Andrews, S.B.Kent, D.J.Craik 291 8003965 Protein Sci An 1H NMR determination of the three-dimensional structures of mirror-image forms of a Leu-5 variant of the trypsin inhibitor from Ecballium elaterium (EETI-II). 3 1994
2LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
2PKA W.Bode, Z.Chen, K.Bartels, C.Kutzbach, G.Schmidt-Kastner, H.Bartunik 237 ( 2PKA ) J.Mol.Biol. Refined 2 Angstroms X-Ray Crystal Structure of Porcine Pancreatic Kallikrein A, a Specific Trypsin-Like Serine Proteinase. Crystallization, Structure Determination, Crystallographic Refinement, Structure and its Comparison with Bovine Trypsin 164 1983
2PTC M.Marquart, J.Walter, J.Deisenhofer, W.Bode, R.Huber 480 ( 2PTC ) Acta Crystallogr.,Sect.B The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors 39 1983
2PTN J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber 1462 ( 2PTN ) Acta Crystallogr.,Sect.B On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography 38 1982
2SEC C.A.McPhalen, M.N.James 6582 3064813 Biochemistry Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. 27 1988
2SGA J.Moult, F.Sussman, M.N.James 555 3892015 J Mol Biol Electron density calculations as an extension of protein structure refinement. Streptomyces griseus protease A at 1.5 A resolution. 182 1985
2SNI C.A.McPhalen, M.N.James 6582 3064813 Biochemistry Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. 27 1988
2SNV L.Tong, G.Wengler, M.G.Rossmann 228 ( 2SNV ) J.Mol.Biol. The Refined Structure of Sindbis Virus Core Protein in Comparison with Other Chymotrypsin-Like Serine Proteinase Structures 230 1993
2SNW H.K.Choi, S.Lee, Y.P.Zhang, B.R.McKinney, G.Wengler, M.G.Rossmann, R.J.Kuhn 151 8831786 J Mol Biol Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. 262 1996
2STA R.Helland, G.I.Berglund, J.Otlewski, W.Apostoluk, O.A.Andersen, N.P.Willassen, A.O.Smalas 139 ( 2STA ) Acta Crystallogr., Sect.D High-Resolution Structures of Three New Trypsin-Squash-Inhibitor Complexes: A Detailed Comparison with Other Trypsins and Their Complexes 55 1999
2STB R.Helland, G.I.Berglund, J.Otlewski, W.Apostoluk, O.A.Andersen, N.P.Willassen, A.O.Smalas 139 ( 2STB ) Acta Crystallogr., Sect.D High-Resolution Structures of Three New Trypsin-Squash-Inhibitor Complexes: A Detailed Comparison with Other Trypsins and Their Complexes 55 1999
2TBS A.O.Smalas, E.S.Heimstad, A.Hordvik, N.P.Willassen, R.Male 149 7846025 Proteins Cold adaption of enzymes: structural comparison between salmon and bovine trypsins. 20 1994
2TGA J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber 1462 ( 2TGA ) Acta Crystallogr.,Sect.B On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography 38 1982
2TGD M.O.Jones, R.M.Stroud n/a ( 2TGD ) To be Published Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of /Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution n/a n/a
2TGP M.Marquart, J.Walter, J.Deisenhofer, W.Bode, R.Huber 480 ( 2TGP ) Acta Crystallogr.,Sect.B The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors 39 1983
2TGT J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber 1462 ( 2TGT ) Acta Crystallogr.,Sect.B On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography 38 1982
2THF E.R.Guinto, S.Caccia, T.Rose, K.Futterer, G.Waksman, E.Di Cera 1852 10051558 Proc Natl Acad Sci U S A Unexpected crucial role of residue 225 in serine proteases. 96 1999
2TIO G.Zhu, Q.Huang, Z.Wang, M.Qian, Y.Jia, Y.Tang 142 9920392 Biochim Biophys Acta X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. 1429 1998
2TLD Y.Takeuchi, T.Nonaka, K.T.Nakamura, S.Kojima, K.Miura, Y.Mitsui 4407 1584773 Proc Natl Acad Sci U S A Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin. 89 1992
2TPI J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber 1462 ( 2TPI ) Acta Crystallogr.,Sect.B On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography 38 1982
2TRM S.Sprang, T.Standing, R.J.Fletterick, R.M.Stroud, J.Finer-Moore, N.H.Xuong, R.Hamlin, W.J.Rutter, C.S.Craik 905 3112942 Science The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis. 237 1987
2VGC V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
2WBC J.K.Dattagupta, A.Podder, C.Chakrabarti, U.Sen, S.K.Dutta, M.Singh 521 ( 2WBC ) Acta Crystallogr.,Sect.D Structure of a Kunitz-Type Chymotrypsin from Winged Bean Seeds at 2.95 A Resolution 52 1996
3BTD R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTD ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTE R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTE ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTF R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTF ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTG R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTG ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTH R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTH ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTK R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTK ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTM R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTM ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTQ R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTQ ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTT R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTT ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3BTW R.Helland, J.Otlewski, O.Sundheim, M.Dadlez, A.O.Smalas 923 ( 3BTW ) J.Mol.Biol. The Crystal Structures of the Complexes between Bovine Beta-Trypsin and Ten P1 Variants of Bpti 287 1999
3CAA C.M.Lukacs, J.Q.Zhong, M.I.Plotnick, H.Rubin, B.S.Cooperman, D.W.Christianson 888 8836107 Nat Struct Biol Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement. 3 1996
3CI2 S.Ludvigsen, H.Y.Shen, M.Kjaer, J.C.Madsen, F.M.Poulsen 621 1748996 J Mol Biol Refinement of the three-dimensional solution structure of barley serine proteinase inhibitor 2 and comparison with the structures in crystals. 222 1991
3CTI M.Nilges, J.Habazettl, A.T.Brunger, T.A.Holak 499 2051485 J Mol Biol Relaxation matrix refinement of the solution structure of squash trypsin inhibitor. 219 1991
3EST E.Meyer, G.Cole, R.Radhakrishnan, O.Epp 26 3271103 Acta Crystallogr B Structure of native porcine pancreatic elastase at 1.65 A resolutions. 44 1988
3GCH B.L.Stoddard, J.Bruhnke, N.Porter, D.Ringe, G.A.Petsko n/a ( 3GCH ) To be Published Chemistry of Caged Enzymes. Binding of Photoreversible Cinnamates to Chymotrypsin n/a n/a
3GCT M.M.Dixon, R.G.Brennan, B.W.Matthews 89 1888717 Int J Biol Macromol Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH. 13 1991
3HAT I.I.Mathews, A.Tulinsky n/a ( 3HAT ) To be Published Active Site Mimetic Inhibition of Thrombin n/a n/a
3HTC T.Rydel, K.G.Ravichandran, A.Tulinsky, W.Bode, R.Huber, C.Roitsch, J.W.Fenton /II 277 ( 3HTC ) Science The Structure of a Complex of Recombinant Hirudin and Human Alpha-Thrombin 249 1990
3LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
3PTB M.Marquart, J.Walter, J.Deisenhofer, W.Bode, R.Huber 480 ( 3PTB ) Acta Crystallogr.,Sect.B The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors 39 1983
3PTN J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber 1462 ( 3PTN ) Acta Crystallogr.,Sect.B On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography 38 1982
3RP2 S.J.Remington, R.G.Woodbury, R.A.Reynolds, B.W.Matthews, H.Neurath 8097 3233198 Biochemistry The structure of rat mast cell protease II at 1.9-A resolution. 27 1988
3SGA M.N.James, A.R.Sielecki, G.D.Brayer, L.T.Delbaere, C.A.Bauer 43 6783761 J Mol Biol Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. 144 1980
3SGB R.J.Read, M.Fujinaga, A.R.Sielecki, M.N.G.James 4420 ( 3SGB ) Biochemistry Structure of the Complex of Streptomyces Griseus Protease B and the Third Domain of the Turkey Ovomucoid Inhibitor at 1.8 Angstroms Resolution 22 1983
3SSI T.Suzuki n/a ( 3SSI ) To be Published Structural Modulation of the Protein Proteinase Inhibitor Ssi (Streptomyces Subtilisin Inhibitor) n/a n/a
3TGI A.Pasternak, D.Ringe, L.Hedstrom n/a ( 3TGI ) To be Published Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure n/a n/a
3TGJ A.Pasternak, D.Ringe, L.Hedstrom n/a ( 3TGJ ) To be Published Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure n/a n/a
3TGK A.Pasternak, A.White, C.J.Jeffery, N.Medina, M.Cahoon, D.Ringe, L.Hedstrom 1331 ( 3TGK ) Protein Sci. The Energetic Cost of Induced Fit Catalysis: Crystal Structures of Trypsinogen Mutants with Enhanced Activity and Inhibitor Affinity 10 2001
3TPI M.Marquart, J.Walter, J.Deisenhofer, W.Bode, R.Huber 480 ( 3TPI ) Acta Crystallogr.,Sect.B The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors 39 1983
3VGC V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
3VSB V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
4CAA C.M.Lukacs, J.Q.Zhong, M.I.Plotnick, H.Rubin, B.S.Cooperman, D.W.Christianson 888 8836107 Nat Struct Biol Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement. 3 1996
4CHA H.Tsukada, D.M.Blow 703 4046030 J Mol Biol Structure of alpha-chymotrypsin refined at 1.68 A resolution. 184 1985
4EST L.H.Takahashi, R.Radhakrishnan, R.E.Rosenfield Jr., E.F.Meyer Jr. 7610 2611205 Biochemistry Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate. 28 1989
4GCH B.L.Stoddard, J.Bruhnke, N.Porter, D.Ringe, G.A.Petsko 4871 2364065 Biochemistry Structure and activity of two photoreversible cinnamates bound to chymotrypsin. 29 1990
4HTC T.J.Rydel, A.Tulinsky, W.Bode, R.Huber 583 ( 4HTC ) J.Mol.Biol. The Refined Structure of the Hirudin-Thrombin Complex 221 1991
4PTI M.Marquart, J.Walter, J.Deisenhofer, W.Bode, R.Huber 480 ( 4PTI ) Acta Crystallogr.,Sect.B The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors 39 1983
4SGA M.N.James, A.R.Sielecki, G.D.Brayer, L.T.Delbaere, C.A.Bauer 43 6783761 J Mol Biol Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. 144 1980
4SGB H.M.Greenblatt, C.A.Ryan, M.N.James 201 2494344 J Mol Biol Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution. 205 1989
4TPI W.Bode, J.Walter, R.Huber, H.R.Wenzel, H.Tschesche 185 ( 4TPI ) Eur.J.Biochem. The Refined 2.2-Angstroms (0.22-Nm) X-Ray Crystal Structure of the Ternary Complex Formed by Bovine Trypsinogen, Valine-Valine and the Arg==15== Analogue of Bovine Pancreatic Trypsin Inhibitor 144 1984
4VGC V.S.Stoll, B.T.Eger, R.C.Hynes, V.Martichonok, J.B.Jones, E.F.Pai 451 9425066 Biochemistry Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. 37 1998
4WBC S.Ravichandran, U.Sen, C.Chakrabarti, J.K.Dattagupta 1814 ( 4WBC ) Acta Crystallogr., Sect.D Cryocrystallography of a Serine Protease Inhibitor: The 90 K Structure of Winged Bean Chymotrypsin Inhibitor (Wci) at 2.13 A Resolution 55 1999
5CHA R.A.Blevins, A.Tulinsky 4264 3980476 J Biol Chem The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution. 260 1985
5EST L.H.Takahashi, R.Radhakrishnan, R.E.Rosenfield Jr., E.F.Meyer Jr. 7610 2611205 Biochemistry Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate. 28 1989
5GCH B.L.Stoddard, J.Bruhnke, P.Koenig, N.Porter, D.Ringe, G.A.Petsko n/a ( 5GCH ) To be Published Chemistry of Caged Enzymes /II. Photoactivation of Inhibited Chymotrypsin n/a n/a
5GDS G.De Simone, A.Lombardi, S.Galdiero, F.Nastri, R.Della Morte, N.Staiano, C.Pedone, M.Bolognesi, V.Pavone 243 9521099 Protein Sci Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex. 7 1998
5LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
5PTI A.Wlodawer, J.Walter, R.Huber, L.Sjolin 301 6210373 J Mol Biol Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. 180 1984
5PTP J.S.Finer-Moore, A.A.Kossiakoff, J.H.Hurley, T.Earnest, R.M.Stroud 203 1557349 Proteins Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. 12 1992
5SGA M.N.James, A.R.Sielecki, G.D.Brayer, L.T.Delbaere, C.A.Bauer 43 6783761 J Mol Biol Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. 144 1980
6CHA A.Tulinsky, R.A.Blevins 7737 3584139 J Biol Chem Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution. 262 1987
6EST I.Li De La Sierra, E.Papamichael, C.Sakarelos, J.-L.Dimicoli, T.Prange 36 ( 6EST ) J.Mol.Recog. Interaction of the Peptide /Cf3-Leu-Ala-/Nh-C6H4-Cf3(/Tfla) with Porcine Pancreatic Elastase. X-Ray Studies at 1.8 Angstroms 3 1990
6GCH K.Brady, A.Z.Wei, D.Ringe, R.H.Abeles 7600 2271520 Biochemistry Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. 29 1990
6LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
6PTI A.Wlodawer, J.Nachman, G.L.Gilliland, W.Gallagher, C.Woodward 469 2448484 J Mol Biol Structure of form III crystals of bovine pancreatic trypsin inhibitor. 198 1987
7API R.Engh, H.Lobermann, M.Schneider, G.Wiegand, R.Huber, C.B.Laurell 407 2785270 Protein Eng The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. 2 1989
7EST I.Li De La Sierra, E.Papamichael, C.Sakarelos, J.-L.Dimicoli, T.Prange 36 ( 7EST ) J.Mol.Recog. Interaction of the Peptide /Cf3-Leu-Ala-/Nh-C6H4-Cf3(/Tfla) with Porcine Pancreatic Elastase. X-Ray Studies at 1.8 Angstroms 3 1990
7GCH K.Brady, A.Z.Wei, D.Ringe, R.H.Abeles 7600 2271520 Biochemistry Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. 29 1990
7LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
7PTI C.Eigenbrot, M.Randal, A.A.Kossiakoff 591 1699222 Protein Eng Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A. 3 1990
8API R.Engh, H.Lobermann, M.Schneider, G.Wiegand, R.Huber, C.B.Laurell 407 2785270 Protein Eng The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. 2 1989
8EST J.C.Powers, J.Oleksyszyn, S.L.Narasimhan, C.M.Kam 3108 2337582 Biochemistry Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin. 29 1990
8GCH M.Harel, C.T.Su, F.Frolow, I.Silman, J.L.Sussman 5217 2036388 Biochemistry Gamma-chymotrypsin is a complex of alpha-chymotrypsin with its own autolysis products. 30 1991
8LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
8PTI D.Housset, K.S.Kim, J.Fuchs, C.Woodward, A.Wlodawer 757 1714504 J Mol Biol Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor. 220 1991
9API R.Engh, H.Lobermann, M.Schneider, G.Wiegand, R.Huber, C.B.Laurell 407 2785270 Protein Eng The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. 2 1989
9EST J.Vijayalakshmi, E.F.Meyer Jr., C.M.Kam, J.C.Powers 2175 1998677 Biochemistry Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex. 30 1991
9LPR R.Bone, A.Fujishige, C.A.Kettner, D.A.Agard 10388 1931963 Biochemistry Structural basis for broad specificity in alpha-lytic protease mutants. 30 1991
9PTI C. Eigenbrot, M. Randal, A. A. Kossiakoff n/a ( 9PTI ) n/a Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor n/a n/a

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PDB Molecule of the Month October 2003, by David S. Goodsell

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