Virtuelle (Nano) Welten: PDB Molecule of the Month 17: Cyclooxygenase

PDB ID	Authors	First Page	Journal Name	Title	Volume No	Publication Year
1CQE	D.Picot, P.J.Loll, R.M.Garavito	243	Nature	The X-Ray Crystal Structure of the Membrane Protein Prostaglandin H2 Synthase-1	367	1994
1CVU	J.R.Kiefer, J.L.Pawlitz, K.T.Moreland, R.A.Stegeman, J.K.Gierse, W.F.Hood, J.K.Gierse, A.M.Stevens, D.C.Goodwin, S.W.Rowlinson, L.J.Marnett, W.C.Stallings, R.G.Kurumbail	97	Nature	Structural Insights Into the Stereochemistry of the Cyclooxygenase Reaction	405	2000
1CX2	R.G.Kurumbail, A.M.Stevens, J.K.Gierse, J.J.McDonald, R.A.Stegeman, J.Y.Pak, D.Gildehaus, J.M.Miyashiro, T.D.Penning, K.Seibert, P.C.Isakson, W.C.Stallings	644	Nature	Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents.	384	1996
1DDX	J.R.Kiefer, J.L.Pawlitz, K.T.Moreland, R.A.Stegeman, W.F.Hood, J.K.Gierse, A.M.Stevens, D.C.Goodwin, S.W.Rowlinson, L.J.Marnett, W.C.Stallings, R.G.Kurumbail	97	Nature	Structural Insights Into the Stereochemistry of the Cyclooxygenase Reaction	405	2000
1DIY	M.G.Malkowski, S.L.Ginell, W.L.Smith, R.M.Garavito	1933	Science	The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase.	289	2000
1EQG	B.S.Selinsky, K.Gupta, C.T.Sharkey, P.J.Loll	5172	Biochemistry	Structural Analysis of Nsaid Binding by Prostaglandin H2 Synthase: Time-Dependent and Time-Independent Inhibitors Elicit Identical Enzyme Conformations	40	2001
1EQH	B.S.Selinsky, K.Gupta, C.T.Sharkey, P.J.Loll	5172	Biochemistry	Structural Analysis of Nsaid Binding by Prostaglandin H2 Synthase: Time-Dependent and Time-Independent Inhibitors Elicit Identical Enzyme Conformations	40	2001
1FE2	E.D.Thuresson, M.G.Malkowski, K.M.Lakkides, C.J.Rieke, A.M.Mulichak, S.L.Ginell, R.M.Garavito, W.L.Smith	10358	J.Biol.Chem.	Mutational and X-Ray Crystallographic Analysis of the Interaction of Dihomo-Gamma-Linolenic Acid with Prostaglandin Endoperoxide H Synthases.	276	2001
1PGE	P.J.Loll, D.Picot, O.Ekabo, R.M.Garavito	7330	Biochemistry	Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.	35	1996
1PGF	P.J.Loll, D.Picot, O.Ekabo, R.M.Garavito	7330	Biochemistry	Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.	35	1996
1PGG	P.J.Loll, D.Picot, O.Ekabo, R.M.Garavito	7330	Biochemistry	Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.	35	1996
1PRH	D.Picot, P.J.Loll, R.M.Garavito	243	Nature	The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.	367	1994
1PTH	P.J.Loll, D.Picot, R.M.Garavito	637	Nat Struct Biol	The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase.	2	1995
3PGH	R.G.Kurumbail, A.M.Stevens, J.K.Gierse, J.J.McDonald, R.A.Stegeman, J.Y.Pak, D.Gildehaus, J.M.Miyashiro, T.D.Penning, K.Seibert, P.C.Isakson, W.C.Stallings	644	Nature	Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents.	384	1996
4COX	R.G.Kurumbail, A.M.Stevens, J.K.Gierse, J.J.McDonald, R.A.Stegeman, J.Y.Pak, D.Gildehaus, J.M.Miyashiro, T.D.Penning, K.Seibert, P.C.Isakson, W.C.Stallings	644	Nature	Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents.	384	1996
5COX	R.G.Kurumbail, A.M.Stevens, J.K.Gierse, J.J.McDonald, R.A.Stegeman, J.Y.Pak, D.Gildehaus, J.M.Miyashiro, T.D.Penning, K.Seibert, P.C.Isakson, W.C.Stallings	644	Nature	Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents.	384	1996
6COX	R.G.Kurumbail, A.M.Stevens, J.K.Gierse, J.J.McDonald, R.A.Stegeman, J.Y.Pak, D.Gildehaus, J.M.Miyashiro, T.D.Penning, K.Seibert, P.C.Isakson, W.C.Stallings	644	Nature	Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents.	384	1996