Human V kappa Germline Sequences (VBase)
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Kabat V kappa 123456789012345678901234567 777777 89012345678901234567890 123456789012345678 901234567890123456789012345555555
abcd4f abcdef
CDR (x) ....:....|....:....|...xxxxxxxxxxxxxxxxxxx..:....|....:..xxxxxxxxxxxxxxx..:....|....:....|....:....|....:.xxxxxxxxxxxxx
11111111111111111111
11111111112222222222333333333344444444445555555555666666666677777777778888888888999999999900000000001111111111
AH0 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
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VBase_VK1_1 2-1-(1) O12 DIQMTQSPSSLSASVGDRVTITCRASQ..SISS......YLNWYQQKPGKAPKLLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQSYSTP.....
VBase_VK1_2 2-1-(1) O2 DIQMTQSPSSLSASVGDRVTITCRASQ..SISS......YLNWYQQKPGKAPKLLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQSYSTP.....
VBase_VK1_3 2-1-(1) O18 DIQMTQSPSSLSASVGDRVTITCQASQ..DISN......YLNWYQQKPGKAPKLLIYD........ASNLETGVPSRFSGSGSG..TDFTFTISSLQPEDIATYYCQQYDNLP.....
VBase_VK1_4 2-1-(1) O8 DIQMTQSPSSLSASVGDRVTITCQASQ..DISN......YLNWYQQKPGKAPKLLIYD........ASNLETGVPSRFSGSGSG..TDFTFTISSLQPEDIATYYCQQYDNLP.....
VBase_VK1_5 2-1-(U) A20 DIQMTQSPSSLSASVGDRVTITCRASQ..GISN......YLAWYQQKPGKVPKLLIYA........ASTLQSGVPSRFSGSGSG..TDFTLTISSLQPEDVATYYCQKYNSAP.....
VBase_VK1_6 2-1-(1) A30 DIQMTQSPSSLSASVGDRVTITCRASQ..GIRN......DLGWYQQKPGKAPKRLIYA........ASSLQSGVPSRFSGSGSG..TEFTLTISSLQPEDFATYYCLQHNSYP.....
VBase_VK1_7 2-1-(1) L14 NIQMTQSPSAMSASVGDRVTITCRARQ..GISN......YLAWFQQKPGKVPKHLIYA........ASSLQSGVPSRFSGSGSG..TEFTLTISSLQPEDFATYYCLQHNSYP.....
VBase_VK1_8 2-1-(1) L1 DIQMTQSPSSLSASVGDRVTITCRASQ..GISN......YLAWFQQKPGKAPKSLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQYNSYP.....
VBase_VK1_9 2-1-(1) L15 DIQMTQSPSSLSASVGDRVTITCRASQ..GISS......WLAWYQQKPEKAPKSLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQYNSYP.....
VBase_VK1_10 2-1-(1) L4 AIQLTQSPSSLSASVGDRVTITCRASQ..GISS......ALAWYQQKPGKAPKLLIYD........ASSLESGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQFNSYP.....
VBase_VK1_11 2-1-(1) L18 AIQLTQSPSSLSASVGDRVTITCRASQ..GISS......ALAWYQQKPGKAPKLLIYD........ASSLESGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQFNSYP.....
VBase_VK1_12 2-1-(1) L5 DIQMTQSPSSVSASVGDRVTITCRASQ..GISS......WLAWYQQKPGKAPKLLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQANSFP.....
VBase_VK1_13 2-1-(1) L19 DIQMTQSPSSVSASVGDRVTITCRASQ..GISS......WLAWYQQKPGKAPKLLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCQQANSFP.....
VBase_VK1_14 2-1-(1) L8 DIQLTQSPSFLSASVGDRVTITCRASQ..GISS......YLAWYQQKPGKAPKLLIYA........ASTLQSGVPSRFSGSGSG..TEFTLTISSLQPEDFATYYCQQLNSYP.....
VBase_VK1_15 2-1-(1) L23 AIRMTQSPFSLSASVGDRVTITCWASQ..GISS......YLAWYQQKPAKAPKLFIYY........ASSLQSGVPSRFSGSGSG..TDYTLTISSLQPEDFATYYCQQYYSTP.....
VBase_VK1_16 2-1-(1) L9 AIRMTQSPSSFSASTGDRVTITCRASQ..GISS......YLAWYQQKPGKAPKLLIYA........ASTLQSGVPSRFSGSGSG..TDFTLTISCLQSEDFATYYCQQYYSYP.....
VBase_VK1_17 U-1-(1) L24 VIWMTQSPSLLSASTGDRVTISCRMSQ..GISS......YLAWYQQKPGKAPELLIYA........ASTLQSGVPSRFSGSGSG..TDFTLTISCLQSEDFATYYCQQYYSFP.....
VBase_VK1_18 2-1-(1) L11 AIQMTQSPSSLSASVGDRVTITCRASQ..GIRN......DLGWYQQKPGKAPKLLIYA........ASSLQSGVPSRFSGSGSG..TDFTLTISSLQPEDFATYYCLQDYNYP.....
VBase_VK1_19 2-1-(U) L12 DIQMTQSPSTLSASVGDRVTITCRASQ..SISS......WLAWYQQKPGKAPKLLIYD........ASSLESGVPSRFSGSGSG..TEFTLTISSLQPDDFATYYCQQYNSYS.....
VBase_VK2_1 3-1-(1) O11 DIVMTQTPLSLPVTPGEPASISCRSSQ..SLLDSDDGNTYLDWYLQKPGQSPQLLIYT........LSYRASGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQRIEFP.....
VBase_VK2_2 3-1-(1) O1 DIVMTQTPLSLPVTPGEPASISCRSSQ..SLLDSDDGNTYLDWYLQKPGQSPQLLIYT........LSYRASGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQRIEFP.....
VBase_VK2_3 4-1-(1) A17 DVVMTQSPLSLPVTLGQPASISCRSSQ..SLVYSD.GNTYLNWFQQRPGQSPRRLIYK........VSNRDSGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQGTHWP.....
VBase_VK2_4 4-1-(1) A1 DVVMTQSPLSLPVTLGQPASISCRSSQ..SLVYSD.GNTYLNWFQQRPGQSPRRLIYK........VSNWDSGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQGTHWP.....
VBase_VK2_5 4-1-(1) A18 DIVMTQTPLSLSVTPGQPASISCKSSQ..SLLHSD.GKTYLYWYLQKPGQSPQLLIYE........VSSRFSGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQGIHLP.....
VBase_VK2_6 4-1-(1) A2 DIVMTQTPLSLSVTPGQPASISCKSSQ..SLLHSD.GKTYLYWYLQKPGQPPQLLIYE........VSNRFSGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQSIQLP.....
VBase_VK2_7 4-1-(1) A19 DIVMTQSPLSLPVTPGEPASISCRSSQ..SLLHSN.GYNYLDWYLQKPGQSPQLLIYL........GSNRASGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQALQTP.....
VBase_VK2_8 4-1-(1) A3 DIVMTQSPLSLPVTPGEPASISCRSSQ..SLLHSN.GYNYLDWYLQKPGQSPQLLIYL........GSNRASGVPDRFSGSGSG..TDFTLKISRVEAEDVGVYYCMQALQTP.....
VBase_VK2_9 4-1-(1) A23 DIVMTQTPLSSPVTLGQPASISCRSSQ..SLVHSD.GNTYLSWLQQRPGQPPRLLIYK........ISNRFSGVPDRFSGSGAG..TDFTLKISRVEAEDVGVYYCMQATQFP.....
VBase_VK3_1 6-1-(1) A27 EIVLTQSPGTLSLSPGERATLSCRASQ..SVSS.....SYLAWYQQKPGQAPRLLIYG........ASSRATGIPDRFSGSGSG..TDFTLTISRLEPEDFAVYYCQQYGSSP.....
VBase_VK3_2 6-1-(1) A11 EIVLTQSPATLSLSPGERATLSCGASQ..SVSS.....SYLAWYQQKPGLAPRLLIYD........ASSRATGIPDRFSGSGSG..TDFTLTISRLEPEDFAVYYCQQYGSSP.....
VBase_VK3_3 2-1-(1) L2 EIVMTQSPATLSVSPGERATLSCRASQ..SVSS......NLAWYQQKPGQAPRLLIYG........ASTRATGIPARFSGSGSG..TEFTLTISSLQSEDFAVYYCQQYNNWP.....
VBase_VK3_4 2-1-(1) L16 EIVMTQSPATLSVSPGERATLSCRASQ..SVSS......NLAWYQQKPGQAPRLLIYG........ASTRATGIPARFSGSGSG..TEFTLTISSLQSEDFAVYYCQQYNNWP.....
VBase_VK3_5 2-1-(1) L6 EIVLTQSPATLSLSPGERATLSCRASQ..SVSS......YLAWYQQKPGQAPRLLIYD........ASNRATGIPARFSGSGSG..TDFTLTISSLEPEDFAVYYCQQRSNWP.....
VBase_VK3_6 2-1-(U) L20 EIVLTQSPATLSLSPGERATLSCRASQ..GVSS......YLAWYQQKPGQAPRLLIYD........ASNRATGIPARFSGSGPG..TDFTLTISSLEPEDFAVYYCQQRSNWH.....
VBase_VK3_7 6-1-(1) L25 EIVMTQSPATLSLSPGERATLSCRASQ..SVSS.....SYLSWYQQKPGQAPRLLIYG........ASTRATGIPARFSGSGSG..TDFTLTISSLQPEDFAVYYCQQDYNLP.....
VBase_VK4_1 3-1-(1) B3 DIVMTQSPDSLAVSLGERATINCKSSQ..SVLYSSNNKNYLAWYQQKPGQPPKLLIYW........ASTRESGVPDRFSGSGSG..TDFTLTISSLQAEDVAVYYCQQYYSTP.....
VBase_VK5_1 2-1-(1) B2 ETTLTQSPAFMSATPGDKVNISCKASQ..DID......DDMNWYQQKPGEAAIFIIQE........ATTLVPGIPPRFSGSGYG..TDFTLTINNIESEDAAYYFCLQHDNFP.....
VBase_VK6_1 2-1-(1) A26 EIVLTQSPDFQSVTPKEKVTITCRASQ..SIG......SSLHWYQQKPDQSPKLLIKY........ASQSFSGVPSRFSGSGSG..TDFTLTINSLEAEDAATYYCHQSSSLP.....
VBase_VK6_2 2-1-(1) A10 EIVLTQSPDFQSVTPKEKVTITCRASQ..SIG......SSLHWYQQKPDQSPKLLIKY........ASQSFSGVPSRFSGSGSG..TDFTLTINSLEAEDAATYYCHQSSSLP.....
VBase_VK6_3 2-1-(1) A14 DVVMTQSPAFLSVTPGEKVTITCQASE..GIG......NYLYWYQQKPDQAPKLLIKY........ASQSISGVPSRFSGSGSG..TDFTFTISSLEAEDAATYYCQQGNKHP.....
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AHonegger, June 6, 2001