Human TCR V alpha Germline Sequences (IMGT)
11111
11111111112222222222333 333333333444444444455 55555555 666666666677777777778888888888999999999900000
Kabat VH 12345678901234567890123456789000 123456789012345678901 23456789 012345678901234567890123456789012345678901234
ab
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111111111111111111111
111111111122222222223333333333444444444455555555556666666666777777777788888888889999999999000000000011111111111
AH0 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890
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IMGT_hVA_1-1 AE000658 .GQSLEQP.SEVTAVEGAIVQINCTYQT.SGFY.......GLSWYQQHDGGAPTFLSYNA.......LDGLEE..TGRFSSFLSRSDSYGYLLLQELQMKDSASYFCAVR........
IMGT_hVA_1-2 AE000658 .GQNIDQP.TEMTATEGAIVQINCTYQT.SGFN.......GLFWYQQHAGEAPTFLSYNV.......LDGLEE..KGRFSSFLSRSKGYSYLLLKELQMKDSASYLCAVR........
IMGT_hVA_2 AE000658 .KDQVFQP.STVASSEGAVVEIFCNHSV.SNAY.......NFFWYLHFPGCAPRLLVKG.........SKPSQ..QGRYNMTYER..FSSSLLILQVREADAAVYYCAVE........
IMGT_hVA_3 AE000658 .AQSVAQPEDQVNVAEGNPLTVKCTYSV.SGNP.......YLFWYVQYPNRGLQFLLKYIT.....GDNLVKG..SYGFEAEFNKSQTSFHLKKPSALVSDSALYFCAVRD.......
IMGT_hVA_4 AE000658 .LAKTTQP.ISMDSYEGQEVNITCSHNN.IATN......DYITWYQQFPSQGPRFIIQG........YKTKVT..NEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD.......
IMGT_hVA_5 AE000659 .GEDVEQS.LFLSVREGDSSVINCTYTD.SSST.......YLYWYKQEPGAGLQLLTYIF......SNMDMKQ..DQRLTVLLNKKDKHLSLRIADTQTGDSAIYFCAES........
IMGT_hVA_6 AE000659 .SQKIEQNSEALNIQEGKTATLTCNYTN.YSPA.......YLQWYRQDPGRGPVFLLLIR......ENEKEKR..KERLKVTFDTTLKQSLFHITASQPADSATYLCALD........
IMGT_hVA_7 AE000659 .ENQVEHSPHFLGPQQGDVASMSCTYSV.SRFN.......NLQWYRQNTGMGPKHLLSMY......SAGYEKQ..KGRLNATLLK..NGSSLYITAVQPEDSATYFCAVD........
IMGT_hVA_8-1 AE000659 .AQSVSQHNHHVILSEAASLELGCNYSY.GGTV.......NLFWYVQYPGQHLQLLLKYFS.....GDPLVKG..IKGFEAEFIKSKFSFNLRKPSVQWSDTAEYFCAVN........
IMGT_hVA_8-2 AE000659 .AQSVTQLDSHVSVSEGTPVLLRCNYSS.SYSP.......SLFWYVQHPNKGLQLLLKYTS.....AATLVKG..INGFEAEFKKSETSFHLTKPSAHMSDAAEYFCVVS........
IMGT_hVA_8-3 AE000659 .AQSVTQPDIHITVSEGASLELRCNYSY.GATP.......YLFWYVQSPGQGLQLLLKYFS.....GDTLVQG..IKGFEAEFKRSQSSFNLRKPSVHWSDAAEYFCAVG........
IMGT_hVA_8-4 AE000659 .AQSVTQLGSHVSVSEGALVLLRCNYSS.SVPP.......YLFWYVQYPNQGLQLLLKYTS.....AATLVKG..INGFEAEFKKSETSFHLTKPSAHMSDAAEYFCAVS........
IMGT_hVA_8-6 X02850 .AQSVTQLDSQVPVFEEAPVELRCNYSS.SVSV.......YLFWYVQYPNQGLQLLLKYLS.....GSTLVES..INGFEAEFNKSQTSFHLRKPSVHISDTAEYFCAVS........
IMGT_hVA_8-7 AE000660 .TQSVTQLDGHITVSEEAPLELKCNYSY.SGVP.......SLFWYVQYSSQSLQLLLKDLT.....EATQVKG..IRGFEAEFKKSETSFYLRKPSTHVSDAAEYFCAVGDR......
IMGT_hVA_9-1 AE000659 .GDSVVQTEGQVLPSEGDSLIVNCSYET.TQYP.......SLFWYVQYPGEGPQLHLKAM......KANDKGR..NKGFEAMYRKETTSFHLEKDSVQESDSAVYFCALS........
IMGT_hVA_9-2 AE000659 .GNSVTQMEGPVTLSEEAFLTINCTYTA.TGYP.......SLFWYVQYPGEGLQLLLKAT......KADDKGS..NKGFEATYRKETTSFHLEKGSVQVSDSAVYFCALS........
IMGT_hVA_10 AE000659 .KNQVEQSPQSLIILEGKNCTLQCNYTV.SPFS.......NLRWYKQDTGRGPVSLTIMT......FSENTKS..NGRYTATLDADTKQSSLHITASQLSDSASYICVVS........
IMGT_hVA_11 AE000659 .LHTLEQSPSFLNIQEGMHAVLNCTYQE.RTLF.......NFHWFRQDPGRRLVSLTLIQ......SSQKEQG..DKYFKELLGKEKFYSVWNIAASHLGDSATYFCAL.........
IMGT_hVA_12-1 AE000659 .RKEVEQDPGPFNVPEGATVAFNCTYSN.SASQ.......SFFWYRQDCRKEPKLLMSV........YSSGNE..DGRFTAQLNRASQYISLLIRDSKLSDSATYLCVVN........
IMGT_hVA_12-2 AE000659 .QKEVEQNSGPLSVPEGAIASLNCTYSD.RGSQ.......SFFWYRQYSGKSPELIMFIY.......SNGDKE..DGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVN........
IMGT_hVA_12-3 X06193 .QKEVEQDPGPLSVPEGAIVSLNCTYSN.SAFQ.......YFMWYRQYSRKGPELLMYTY.......SSGNKE..DGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMS........
IMGT_hVA_13-1 AE000659 .GENVEQHPSTLSVQEGDSAVIKCTYSD.SASN.......YFPWYKQELGKGPQLIIDIR......SNVGEKK..DQRIAVTLNKTAKHFSLHITETQPEDSAVYFCAAS........
IMGT_hVA_13-2 AE000659 .GESVGLHLPTLSVQEGDNSIINCAYSN.SASD.......YFIWYKQESGKGPQFIIDIR......SNMDKRQ..GQRVTVLLNKTVKHLSLQIAATQPGDSAVYFCAEN........
IMGT_hVA_14 DV4 M21626 .AQKITQTQPGMFVQEKEAVTLDCTYDT.SDPS......YGLFWYKQPSSGEMIFLIYQGS.....YDQQNAT..EGRYSLNFQKARKSANLVISASQLGDSAMYFCAMRE.......
IMGT_hVA_16 AE000659 .AQRVTQPEKLLSVFKGAPVELKCNYSY.SGSP.......ELFWYVQYSRQRLQLLLRH.........ISRES..IKGFTADLNKGETSFHLKKPFAQEEDSAMYYCALS........
IMGT_hVA_17 AE000660 .SQQGEEDPQALSIQEGENATMNCSYKT.SIN........NLQWYRQNSGRGLVHLILIR......SNEREKH..SGRLRVTLDTSKKSSSLLITASRAADTASYFCATD........
IMGT_hVA_18 AE000660 .GDSVTQTEGPVTLPERAALTLNCTYQS.SYST.......FLFWYVQYLNKEPELLLKSS.......ENQETD..SRGFQASPIKSDSSFHLEKPSVQLSDSAVYYCALR........
IMGT_hVA_19 AE000660 .AQKVTQAQTEISVVEKEDVTLDCVYET.RDTT......YYLFWYKQPPSGELVFLIRRNS.....FDEQNEI..SGRYSWNFQKSTSSFNFTITASQVVDSAVYFCALSE.......
IMGT_hVA_20 AE000660 .EDQVTQSPEALRLQEGESSSLNCSYTV.SGLR.......GLFWYRQDPGKGPEFLFTLY......SAGEEKE..KERLKATLTK..KESFLHITAPKPEDSATYLCAVQ........
IMGT_hVA_21 AE000660 .KQEVTQIPAALSVPEGENLVLNCSFTD.SAIY.......NLQWFRQDPGKGLTSLLLIQ......SSQREQT..SGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVR........
IMGT_hVA_22 AE000660 .GIQVEQSPPDLILQEGANSTLRCNFSD.SVN........NLQWFHQNPWGQLINLFYI........PSGTKQ..NGRLSATTVATERYSLLYISSSQTTDSGVYFCAVE........
IMGT_hVA_23 DV6 AE000660 .QQQVKQSPQSLIVQKGGISIINCAYEN.TAFD.......YFPWYQQFPGKGPALLIAIR......PDVSEKK..EGRFTISFNKSAKQFSLHIMDSQPGDSATYFCAAS........
IMGT_hVA_24 AE000660 .ILNVEQSPQSLHVQEGDSTNFTCSFPS.SNFY.......ALHWYRWETAKSPEALFVMT......LNGDEKK..KGRISATLNTKEGYSYLYIKGSQPEDSATYLCAF.........
IMGT_hVA_25 AE000660 .GQQVMQIPQYQHVQEGEDFTTYCNSST.TLS........NIQWYKQRPGGHPVFLIQLV......KSGEVKK..QKRLTFQFGEAKKNSSLHITATQTTDVGTYFCAG.........
IMGT_hVA_26-1 AE000660 .DAKTTQP.PSMDCAEGRAANLPCNHST.ISGN......EYVYWYRQIHSQGPQYIIHG........LKNNET..NEMASLIITEDRKSSTLILPHATLRDTAVYYCIVRV.......
IMGT_hVA_26-2 AE000660 .DAKTTQP.NSMESNEEEPVHLPCNHST.ISGT......DYIHWYRQLPSQGPEYVIHG........LTSNVN..NRMASLAIAEDRKSSTLILHRATLRDAAVYYCILRD.......
IMGT_hVA_27 AE000660 .TQLLEQSPQFLSIQEGENLTVYCNSSS.VFS........SLQWYRQEPGEGPVLLVTVV......TGGEVKK..LKRLTFQFGDARKDSSLHITAAQPGDTGLYLCAG.........
IMGT_hVA_29 DV5 AE000660 .DQQVKQNSPSLSVQEGRISILNCDYTN.SMFD.......YFLWYKKYPAEGPTFLISIS......SIKDKNE..DGRFTVFLNKSAKHLSLHIVPSQPGDSAVYFCAAS........
IMGT_hVA_30 AE000660 ..QQPVQSPQAVILREGEDAVINCSSSK.ALY........SVHWYRQKHGEAPVFLMILL......KGGEQKG..HEKISASFNEKKQQSSLYLTASQLSYSGTYFCGTE........
IMGT_hVA_34 AE000660 .SQELEQSPQSLIVQEGKNLTINCTSSK.TLY........GLYWYKQKYGEGLIFLMMLQ......KGGEEKS..HEKITAKLDEKKQQSSLHITASQPSHAGIYLCGAD........
IMGT_hVA_35 AE000660 .GQQLNQSPQSMFIQEGEDVSMNCTSSS.IFN........TWLWYKQEPGEGPVLLIALY......KAGELTS..NGRLTAQFGITRKDSFLNISASIPSDVGIYFCAGQ........
IMGT_hVA_36 DV7 AE000660 .EDKVVQSPLSLVVHEGDTVTLNCSYEV.TNFR.......SLLWYKQEKKAP.TFLFMLT......SSGIEKK..SGRLSSILDKKELSSILNITATQTGDSAIYLCAVE........
IMGT_hVA_38-1 AE000661 .AQTVTQSQPEMSVQEAETVTLSCTYDT.SENN......YYLFWYKQPPSRQMILVIRQEA.....YKQQNAT..ENRFSVNFQKAAKSFSLKISDSQLGDTAMYFCAFMK.......
IMGT_hVA_38-2 DV8 AE000661 .AQTVTQSQPEMSVQEAETVTLSCTYDT.SESD......YYLFWYKQPPSRQMILVIRQEA.....YKQQNAT..ENRFSVNFQKAAKSFSLKISDSQLGDAAMYFCAYRS.......
IMGT_hVA_39 AE000661 .ELKVEQNPLFLSMQEGKNYTIYCNYST.TSD........RLYWYRQDPGKSLESLFVLL......SNGAVKQ..EGRLMASLDTKARLSTLHITAAVHDLSATYFCAVD........
IMGT_hVA_40 X73521 .SNSVKQT.GQITVSEGASVTMNCTYTS.TGYP.......TLFWYVEYPSKPLQLLQR..........ETMEN..SKNFGGGNIKD.KNSPIVKYSVQVSDSAVYYCLLG........
IMGT_hVA_41 AE000661 .KNEVEQSPQNLTAQEGEFITINCSYSV.GIS........ALHWLQQHPGGGIVSLFML........SSGKKK..HGRLIATINIQEKHSSLHITASHPRDSAVYICAVR........
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AHonegger, June 6, 2001